Page last updated: 2024-10-26

diphenhydramine and Emergencies

diphenhydramine has been researched along with Emergencies in 24 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Emergencies: Situations or conditions requiring immediate intervention to avoid serious adverse results.

Research Excerpts

ExcerptRelevanceReference
"5 g diphenhydramine), so that a central anticholinergic syndrome due to an overdose with this drug could be assumed."8.79[An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning]. ( Lang, K; Müller, S; Sigusch, H, 1995)
"5 g diphenhydramine), so that a central anticholinergic syndrome due to an overdose with this drug could be assumed."4.79[An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning]. ( Lang, K; Müller, S; Sigusch, H, 1995)
" Initial electrocardiograms revealed sinus tachycardia at a rate of 180 beats per minute, a prolonged QRS of 130 milliseconds (from a baseline of 65 milliseconds), and a positive terminal R wave in aVR, which later resolved after sodium bicarbonate treatment."3.77Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate. ( Cole, JB; Gross, EA; Smith, SW; Stellpflug, SJ, 2011)
"When compared at 2 and 24 hours, aggressive (20 mg dosed up to four times) IV metoclopramide and 6 mg of subcutaneous sumatriptan relieved migraine headache pain comparably."2.71A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines. ( Bijur, PE; Corbo, J; Esses, D; Friedman, BW; Gallagher, EJ; Lipton, RB; Solorzano, C, 2005)
"Neuroleptic drugs are a known cause of dystonia and are the most frequently encountered trigger."1.30Cocaine-associated dystonic reaction. ( Brady, WJ; DeBehnke, DJ; Fines, RE, 1997)
"Patients with previous anaphylactoid reactions to radiographic contrast media (RCM) are at increased risk for subsequent reactions on repeat exposure."1.27Emergency administration of radiocontrast media in high-risk patients. ( Greenberger, PA; Halwig, JM; Patterson, R; Wallemark, CB, 1986)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's11 (45.83)18.2507
2000's7 (29.17)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madey, JJ1
Price, AB1
Dobson, JV1
Stickler, DE1
McSwain, SD1
Nath, P1
Basher, A1
Harada, M1
Sarkar, S1
Selim, S1
Maude, RJ1
Noiri, E1
Faiz, A1
Cole, JB1
Stellpflug, SJ1
Gross, EA1
Smith, SW1
Friedman, BW1
Corbo, J1
Lipton, RB1
Bijur, PE1
Esses, D1
Solorzano, C1
Gallagher, EJ1
Nakanishi, T1
Yasuda, S1
Kubota, Y1
Kajimoto, A1
Kamo, R1
Kobayashi, H1
Ishii, M1
Knish, P1
Errington, G1
Hannaway, PJ1
Lang, K1
Sigusch, H1
Müller, S1
Becker, DE1
Fines, RE1
Brady, WJ1
DeBehnke, DJ1
Sexton, JD1
Pronchik, DJ1
Biron, CR1
Thomas, P1
McDonough, J1
Higgins, BC1
Myers, JS1
Kearney, K1
Blazys, D1
Bulakhova, EK1
Agafonova, IA1
Carson, L1
Romisher, S1
Felter, R1
Dougherty, J1
Greenberger, PA1
Halwig, JM1
Patterson, R1
Wallemark, CB1
Falleroni, AE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen[NCT01522326]300 participants (Anticipated)Interventional2012-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for diphenhydramine and Emergencies

ArticleYear
Standing orders for allergy symptoms and anaphylaxis in the K through 12 school setting.
    School nurse news, 2005, Volume: 22, Issue:5

    Topics: Anaphylaxis; Anti-Allergic Agents; Clinical Protocols; Curriculum; Diphenhydramine; Education, Nursi

2005
[An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning].
    Deutsche medizinische Wochenschrift (1946), 1995, Dec-08, Volume: 120, Issue:49

    Topics: Adult; Combined Modality Therapy; Diagnosis, Differential; Diphenhydramine; Drug Overdose; Emergenci

1995
Management of immediate allergic reactions.
    Dental clinics of North America, 1995, Volume: 39, Issue:3

    Topics: Adrenergic Agonists; Anaphylaxis; Anti-Allergic Agents; Dental Care; Dental Offices; Diphenhydramine

1995
Treatment of allergic emergencies.
    Modern treatment, 1968, Volume: 5, Issue:5

    Topics: Aminophylline; Anaphylaxis; Antigen-Antibody Reactions; Bronchial Spasm; Diphenhydramine; Drug Hyper

1968

Trials

1 trial available for diphenhydramine and Emergencies

ArticleYear
A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.
    Neurology, 2005, Feb-08, Volume: 64, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dizziness;

2005

Other Studies

19 other studies available for diphenhydramine and Emergencies

ArticleYear
Facial diplegia, pharyngeal paralysis, and ophthalmoplegia after a timber rattlesnake envenomation.
    Pediatric emergency care, 2013, Volume: 29, Issue:11

    Topics: Animals; Antivenins; Child; Combined Modality Therapy; Crotalid Venoms; Crotalus; Crotoxin; Diphenhy

2013
Immediate hypersensitivity reaction following liposomal amphotericin-B (AmBisome) infusion.
    Tropical doctor, 2014, Volume: 44, Issue:4

    Topics: Adult; Amphotericin B; Bangladesh; Child; Diphenhydramine; Emergencies; Epinephrine; Female; Humans;

2014
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha

2009
Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate.
    Pediatric emergency care, 2011, Volume: 27, Issue:12

    Topics: Anticonvulsants; Cholinergic Antagonists; Diphenhydramine; Drug Overdose; Electrocardiography; Emerg

2011
Allergic contact dermatitis presenting in the emergency department.
    Contact dermatitis, 2005, Volume: 52, Issue:1

    Topics: Anti-Allergic Agents; Antipruritics; Dermatitis, Allergic Contact; Diphenhydramine; Emergencies; Eme

2005
Emergency department treatment of anaphylaxis: is epinephrine always indicated?
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:1

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Contraindications; Diphenhyd

2006
Anaphylaxis: statement on initial management in nonhospital settings. Laboratory Centre for Disease Control.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1996, May-15, Volume: 154, Issue:10

    Topics: Adolescent; Age Factors; Anaphylaxis; Anti-Allergic Agents; Bronchodilator Agents; Child; Child, Pre

1996
Cocaine-associated dystonic reaction.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:5

    Topics: Adult; Antiparkinson Agents; Cocaine; Diphenhydramine; Dystonia; Emergencies; Humans; Male

1997
Diphenhydramine-induced psychosis with therapeutic doses.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Diphenhydramine; Drug Combinations; Emergencies; Hum

1997
Allergic reactions to dental materials, drugs require an alert response from practitioner.
    RDH, 1997, Volume: 17, Issue:2

    Topics: Adolescent; Anesthetics, Local; Anti-Bacterial Agents; Contraindications; Dental Materials; Dermatit

1997
Acute facial and upper respiratory tract swelling.
    Australian family physician, 1997, Volume: 26, Issue:12

    Topics: Adrenergic Agonists; Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory A

1997
Emergency! Acetaminophen overdose.
    The American journal of nursing, 1998, Volume: 98, Issue:3

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anorexia Nervosa; Chemical and Drug Induced Liv

1998
Emergency! Prochlorperazine-induced dystonia.
    The American journal of nursing, 1999, Volume: 99, Issue:11

    Topics: Adolescent; Animals; Antiemetics; Diagnosis, Differential; Diphenhydramine; Dystonia; Emergencies; F

1999
Emergency. Chemotherapy-induced hypersensitivity reaction.
    The American journal of nursing, 2000, Volume: 100, Issue:4

    Topics: Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Diphenhydramine; Drug Hypersensitivity; Eme

2000
Asthma and latex allergy.
    Journal of emergency nursing, 2000, Volume: 26, Issue:6

    Topics: Asthma; Bronchodilator Agents; Child; Diphenhydramine; Emergencies; Epinephrine; Histamine H1 Antago

2000
[Wissler's subsepsis allergica as a manifestation of drug allergy].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:3

    Topics: Adult; Aspirin; Diagnosis, Differential; Diphenhydramine; Dipyrone; Drug Hypersensitivity; Emergenci

1992
A 44-year-old man with erythema of the face, neck, and chest, weakness, and palpitations.
    Journal of emergency nursing, 1991, Volume: 17, Issue:2

    Topics: Adult; Animals; Diphenhydramine; Emergencies; Food Contamination; Food Handling; Foodborne Diseases;

1991
Tagamet-induced acute dystonia.
    Annals of emergency medicine, 1987, Volume: 16, Issue:10

    Topics: Adult; Cimetidine; Diphenhydramine; Dystonia; Emergencies; Female; Humans

1987
Emergency administration of radiocontrast media in high-risk patients.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:4

    Topics: Anaphylaxis; Contrast Media; Diphenhydramine; Emergencies; Humans; Prednisone; Premedication; Risk

1986