diphenhydramine has been researched along with Edema, Pulmonary in 21 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we investigated the therapeutic potential of diphenhydramine (DPH), a H(1) receptor antagonist, on taurocholate-induced acute pancreatitis and the underlying mechanisms involved." | 7.76 | Diphenhydramine modulates cytokines and induces apoptosis in experimental acute pancreatitis. ( Bao, P; Dou, K; Gao, Z; Li, R; Tao, K; You, H; You, N; Zhang, M; Zhao, W, 2010) |
| "The injection of ethchlorvynol intravenously in humans and animals causes an increased permeability form of pulmonary edema." | 7.66 | Histamine receptor and prostaglandin synthetase blockers in ethchlorvynol-induced pulmonary edema in canines. ( Fairman, RP; Falls, R; Glauser, FL; Millen, JE, 1980) |
| "Ethchlorvynol (10 mg/kg) causes transient pulmonary hypertension and an increased permeability pulmonary edema in sheep." | 7.66 | Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema. ( Fairman, RP; Falls, RK; Glauser, FL; Millen, JE, 1982) |
| "To see whether antihistamines could prevent and reverse histamine-induced pulmonary edema and increased lung vascular permeability, we compared the effects of a 4-h intravenous infusion of 4 mug/kg per min histamine phosphate on pulmonary hemodynamics, lung lymph flow, lymph and plasma protein content, arterial blood gases, hematocrit, and lung water with the effects of an identical histamine infusion given during an infusion of diphenhydramine or metiamide on the same variables in unanesthetized sheep." | 7.65 | Effects of antihistamines on the lung vascular response to histamine in unanesthetized sheep. Diphenhydramine prevention of pulmonary edema and increased permeability. ( Bowers, RE; Brigham, KL; Owen, PJ, 1976) |
| "In this study, we investigated the therapeutic potential of diphenhydramine (DPH), a H(1) receptor antagonist, on taurocholate-induced acute pancreatitis and the underlying mechanisms involved." | 3.76 | Diphenhydramine modulates cytokines and induces apoptosis in experimental acute pancreatitis. ( Bao, P; Dou, K; Gao, Z; Li, R; Tao, K; You, H; You, N; Zhang, M; Zhao, W, 2010) |
| "The injection of ethchlorvynol intravenously in humans and animals causes an increased permeability form of pulmonary edema." | 3.66 | Histamine receptor and prostaglandin synthetase blockers in ethchlorvynol-induced pulmonary edema in canines. ( Fairman, RP; Falls, R; Glauser, FL; Millen, JE, 1980) |
| "Ethchlorvynol (10 mg/kg) causes transient pulmonary hypertension and an increased permeability pulmonary edema in sheep." | 3.66 | Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema. ( Fairman, RP; Falls, RK; Glauser, FL; Millen, JE, 1982) |
| "To see whether antihistamines could prevent and reverse histamine-induced pulmonary edema and increased lung vascular permeability, we compared the effects of a 4-h intravenous infusion of 4 mug/kg per min histamine phosphate on pulmonary hemodynamics, lung lymph flow, lymph and plasma protein content, arterial blood gases, hematocrit, and lung water with the effects of an identical histamine infusion given during an infusion of diphenhydramine or metiamide on the same variables in unanesthetized sheep." | 3.65 | Effects of antihistamines on the lung vascular response to histamine in unanesthetized sheep. Diphenhydramine prevention of pulmonary edema and increased permeability. ( Bowers, RE; Brigham, KL; Owen, PJ, 1976) |
| "Anidulafungin is an echinocandin antifungal used to treat invasive fungal infections caused by Candida or Aspergillus species." | 1.38 | Flash pulmonary oedema during anidulafungin administration. ( Hindahl, CB; Wilson, JW, 2012) |
| "Diphenhydramine is a drug readily available over the counter in the form of capsules, tablets, and syrup used for allergy relief." | 1.35 | Death of a child from topical diphenhydramine. ( Turner, JW, 2009) |
| "Marked pulmonary edema with visceral congestion was a constant finding." | 1.30 | Diphenhydramine toxicity: comparisons of postmortem findings in diphenhydramine-, cocaine-, and heroin-related deaths. ( Karch, SB, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Elkhazeen, A | 1 |
| Poulos, C | 1 |
| Zhang, X | 1 |
| Cavanaugh, J | 1 |
| Cain, M | 1 |
| Smolarz, BG | 1 |
| Ross, J | 1 |
| Sachinwalla, E | 1 |
| Marcus, A | 1 |
| Abazia, DT | 1 |
| Kamijo, Y | 1 |
| Soma, K | 1 |
| Sato, C | 1 |
| Kurihara, K | 1 |
| Turner, JW | 1 |
| Lann, MA | 1 |
| Martin, A | 1 |
| You, N | 1 |
| Tao, K | 1 |
| Zhao, W | 1 |
| Bao, P | 1 |
| Li, R | 1 |
| You, H | 1 |
| Zhang, M | 1 |
| Gao, Z | 2 |
| Dou, K | 1 |
| Hindahl, CB | 1 |
| Wilson, JW | 1 |
| Borish, L | 1 |
| Matloff, SM | 1 |
| Findlay, SR | 1 |
| Fairman, RP | 3 |
| Falls, R | 1 |
| Millen, JE | 2 |
| Glauser, FL | 3 |
| Falls, RK | 1 |
| Moriuchi, H | 1 |
| Arai, I | 1 |
| Yuizono, T | 1 |
| Karch, SB | 1 |
| Brigham, KL | 2 |
| Oh, TE | 1 |
| Gordon, TP | 1 |
| Burden, PW | 1 |
| Bowers, RE | 1 |
| Owen, PJ | 1 |
| Martins, MA | 1 |
| Silva, PM | 1 |
| Henriques, MG | 1 |
| Cordeiro, RS | 1 |
| Corrêa, FM | 1 |
| Sessler, CN | 1 |
| Bierman, M | 1 |
| Yamamoto, M | 1 |
| Antonio, MP | 1 |
| Fernandes, F | 1 |
| Gonçalves, JA | 1 |
| Rocha e Silva, M | 1 |
| Cohn, AM | 1 |
| Holmberg, G | 1 |
| Wiklund, PE | 1 |
1 review available for diphenhydramine and Edema, Pulmonary
| Article | Year |
|---|---|
A TikTok™ "Benadryl Challenge" death-A case report and review of the literature.
Topics: Adolescent; Autopsy; Diphenhydramine; Female; Forensic Medicine; Humans; Lung; Pulmonary Edema; Youn | 2023 |
20 other studies available for diphenhydramine and Edema, Pulmonary
| Article | Year |
|---|---|
Noncardiogenic pulmonary edema in a patient receiving vancomycin and oxycodone-acetaminophen.
Topics: Acetamides; Acetaminophen; Analgesics; Anti-Infective Agents; Cellulitis; Diphenhydramine; Drug Comb | 2008 |
Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support.
Topics: Acidosis; Adult; Capillary Permeability; Dehydration; Diphenhydramine; Fatal Outcome; Histamine H1 A | 2008 |
Death of a child from topical diphenhydramine.
Topics: Administration, Topical; Brain Edema; Diphenhydramine; Eczema; Forensic Pathology; Forensic Toxicolo | 2009 |
An unusual death involving a sensory deprivation tank.
Topics: Baths; Central Nervous System Depressants; Confined Spaces; Creatinine; Diphenhydramine; Doxylamine; | 2010 |
Diphenhydramine modulates cytokines and induces apoptosis in experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Apoptosis; bcl-2-Associated X Protein; Cytokines; Diphenhydramine; | 2010 |
Flash pulmonary oedema during anidulafungin administration.
Topics: Albuterol; Anidulafungin; Antifungal Agents; Diphenhydramine; Echinocandins; Follow-Up Studies; Hist | 2012 |
Radiographic contrast media-induced noncardiogenic pulmonary edema: case report and review of the literature.
Topics: Cardiac Catheterization; Contrast Media; Diphenhydramine; Furosemide; Humans; Hydroxyzine; Male; Met | 1984 |
Histamine receptor and prostaglandin synthetase blockers in ethchlorvynol-induced pulmonary edema in canines.
Topics: Albumins; Animals; Cimetidine; Cyclooxygenase Inhibitors; Diphenhydramine; Dogs; Ethchlorvynol; Half | 1980 |
Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema.
Topics: Animals; Blood Pressure; Diphenhydramine; Ethchlorvynol; Hypertension, Pulmonary; Indomethacin; Phen | 1982 |
Tranexamic acid attenuates oleic-acid-induced pulmonary extravasation.
Topics: Analysis of Variance; Animals; Capillary Permeability; Diphenhydramine; Disease Models, Animal; Dose | 1995 |
Diphenhydramine toxicity: comparisons of postmortem findings in diphenhydramine-, cocaine-, and heroin-related deaths.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Cocaine; Diphenhydramine; Drug Overdose; Fatal Outcome; | 1998 |
Pulmonary edema: cardiac and noncardiac.
Topics: Animals; Blood Pressure; Capillary Permeability; Diphenhydramine; Endotoxins; Heart Failure; Humans; | 1979 |
Unilateral pulmonary oedema and "Mandrax" poisoning.
Topics: Adult; Diphenhydramine; Drug Combinations; Humans; Male; Methaqualone; Pulmonary Edema | 1978 |
Effects of antihistamines on the lung vascular response to histamine in unanesthetized sheep. Diphenhydramine prevention of pulmonary edema and increased permeability.
Topics: Animals; Diphenhydramine; Histamine; Metiamide; Pulmonary Diffusing Capacity; Pulmonary Edema; Sheep | 1976 |
Plasmodium berghei-infected mice: lack of effect of meclizine and cimetidine on the development of pulmonary oedema.
Topics: Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Hist | 1986 |
Protamine sulfate causes pulmonary hypertension and edema in isolated rat lungs.
Topics: Animals; Blood Pressure; Capillary Permeability; Diphenhydramine; Heparin; Hypertension, Pulmonary; | 1987 |
Pathology of experimental pulmonary bone marrow embolism. I. Initial lesions of the rabbit lung after intravenous infusion of allogeneic bone marrow with special reference to its pathogenesis.
Topics: Animals; Bone Marrow; Capillary Permeability; Diphenhydramine; Embolism, Fat; Endothelium; Female; I | 1985 |
Pharmacologial analysis of the mediators involved in the acute pulmonary edema produced in rats by adrenaline.
Topics: Animals; Cyproheptadine; Diphenhydramine; Epinephrine; Histamine H1 Antagonists; Phenoxybenzamine; P | 1973 |
Concepts in management of burns of the respiratory tract.
Topics: Adolescent; Adult; Aged; Aminophylline; Ampicillin; Burns, Inhalation; Child; Child, Preschool; Dexa | 1973 |
[Treatment of acute poisoning. 8. Intoxications with preparations containing methaqualone].
Topics: Blood Pressure; Diphenhydramine; Hypnotics and Sedatives; Methaqualone; Pulmonary Edema; Respiratory | 1971 |