diphenhydramine has been researched along with Dystonia in 33 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-year-old male receiving aripiprazole, methylphenidate, and clonidine developed acute masseter dystonia inhibiting tracheal intubation after induction of general anesthesia with propofol and rocuronium." | 7.85 | Acute masseter dystonia in a pediatric patient receiving aripiprazole and methylphenidate following induction of general anesthesia. ( Duncan-Wiebe, G; LeRiger, M; Shukry, M; Williams, J, 2017) |
| "To assess the effectiveness of diphenhydramine hydrochloride (Benadryl) in the treatment of patients with idiopathic truncal dystonia." | 7.69 | Diphenhydramine is effective in the treatment of idiopathic dystonia. ( Matsumoto, RR; Sandroni, P; Truong, DD; van den Noort, S, 1995) |
| "We present a case of acute dystonia caused by administration of etoposide in an 11-year-old boy being treated for acute lymphoblastic leukemia." | 7.67 | Acute dystonia from etoposide. ( Ascher, DP; Delaney, RA, 1988) |
| "A 27-year-old man was admitted to the emergency department with a fluphenazine decanoate-induced dystonia." | 7.67 | Unusual treatment response of a severe dystonia to diphenhydramine. ( Bailie, GR; Krenzelok, EP; Lesar, T; Nelson, MV, 1987) |
| "The degree of dystonia was determined by a modified University of Columbia Scale evaluating the baseline score, after placebo and DPH I." | 6.69 | Beneficial effects of diphenhydramine in dystonia. ( Arrebola, M; Díaz, S; Ferrea, M; Grañana, N; Micheli, F; Scorticati, MC; Torres, L, 1999) |
| "Acute dystonia has notably been a challenge in the emergency unit." | 5.72 | Diphenhydramine induced acute dystonia: a case report. ( Dailaty, AA; Daou, R; Helou, M; Khater, DA, 2022) |
| "An 11-year-old male receiving aripiprazole, methylphenidate, and clonidine developed acute masseter dystonia inhibiting tracheal intubation after induction of general anesthesia with propofol and rocuronium." | 3.85 | Acute masseter dystonia in a pediatric patient receiving aripiprazole and methylphenidate following induction of general anesthesia. ( Duncan-Wiebe, G; LeRiger, M; Shukry, M; Williams, J, 2017) |
| "Although diphenhydramine hydrochloride is known to eliminate or reduce the symptoms of dystonia in human patients with acute dystonic reactions and idiopathic torsion dystonia, its mechanism of action is still unclear." | 3.69 | Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine. ( Matsumoto, RR; Stone, MR; Truong, DD; van't Groenewout, JL; Vo, VN, 1995) |
| "A 43-year-old woman with gastroesophageal reflux disease developed a dystonic-like reaction approximately 3 days after starting oral cisapride therapy." | 3.69 | Dystonic-like reaction following cisapride therapy. ( Abercrombie, SA; Bucci, KK; Haverstick, DE, 1995) |
| "We present a case of acute dystonia caused by administration of etoposide in an 11-year-old boy being treated for acute lymphoblastic leukemia." | 3.67 | Acute dystonia from etoposide. ( Ascher, DP; Delaney, RA, 1988) |
| "A 27-year-old man was admitted to the emergency department with a fluphenazine decanoate-induced dystonia." | 3.67 | Unusual treatment response of a severe dystonia to diphenhydramine. ( Bailie, GR; Krenzelok, EP; Lesar, T; Nelson, MV, 1987) |
| "Acute dystonia has notably been a challenge in the emergency unit." | 1.72 | Diphenhydramine induced acute dystonia: a case report. ( Dailaty, AA; Daou, R; Helou, M; Khater, DA, 2022) |
| "She presented with opisthotonus, ataxia, and bidirectional nystagmus." | 1.30 | Dystonic reaction associated with dextromethorphan ingestion in a toddler. ( Diekema, DS; Robertson, WO; Warden, CR, 1997) |
| "Neuroleptic drugs are a known cause of dystonia and are the most frequently encountered trigger." | 1.30 | Cocaine-associated dystonic reaction. ( Brady, WJ; DeBehnke, DJ; Fines, RE, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (39.39) | 18.7374 |
| 1990's | 14 (42.42) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 3 (9.09) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Khater, DA | 3 |
| Daou, R | 3 |
| Dailaty, AA | 3 |
| Helou, M | 3 |
| LeRiger, M | 1 |
| Williams, J | 1 |
| Duncan-Wiebe, G | 1 |
| Shukry, M | 1 |
| Coralic, Z | 1 |
| Kim, AS | 1 |
| Vinson, DR | 1 |
| Jacob, S | 1 |
| Ly, H | 1 |
| Villenueva, RJ | 1 |
| Gupta, HV | 1 |
| Freudenreich, O | 1 |
| Lou, E | 1 |
| Abou-Zeid, N | 1 |
| Dahiya, U | 1 |
| Noronha, P | 1 |
| Corre, KA | 1 |
| Niemann, JT | 1 |
| Bessen, HA | 1 |
| Cohen, GH | 1 |
| Casta, A | 1 |
| Sapire, DW | 1 |
| Talabi, A | 1 |
| Stallworth, HF | 1 |
| Shipko, S | 1 |
| Mancini, JL | 1 |
| Joseph, MM | 1 |
| King, WD | 1 |
| van't Groenewout, JL | 1 |
| Stone, MR | 1 |
| Vo, VN | 1 |
| Truong, DD | 2 |
| Matsumoto, RR | 2 |
| Sandroni, P | 1 |
| van den Noort, S | 1 |
| Bucci, KK | 1 |
| Haverstick, DE | 1 |
| Abercrombie, SA | 1 |
| Moss, W | 1 |
| Ojukwu, C | 1 |
| Chiriboga, CA | 1 |
| Reecer, MV | 1 |
| Clinchot, DM | 1 |
| Tipton, DB | 1 |
| Lang, AE | 1 |
| Warden, CR | 1 |
| Diekema, DS | 1 |
| Robertson, WO | 1 |
| Fines, RE | 2 |
| Brady, WJ | 2 |
| DeBehnke, DJ | 1 |
| Martin, ML | 1 |
| Grañana, N | 1 |
| Ferrea, M | 1 |
| Scorticati, MC | 1 |
| Díaz, S | 1 |
| Arrebola, M | 1 |
| Torres, L | 1 |
| Micheli, F | 1 |
| Burda, A | 1 |
| Webster, K | 1 |
| Leikin, JB | 1 |
| Chan, SB | 1 |
| Stokes, KA | 1 |
| Higgins, BC | 1 |
| Lee, AS | 1 |
| Ott, DA | 1 |
| Goeden, SR | 1 |
| Brady, W | 1 |
| Hall, K | 1 |
| Roila, F | 1 |
| Donati, D | 1 |
| Basurto, C | 1 |
| Del Favero, A | 1 |
| Santora, J | 1 |
| Rozek, S | 1 |
| Samie, MR | 1 |
| Shannon, M | 1 |
| Ascher, DP | 1 |
| Delaney, RA | 1 |
| Bailie, GR | 1 |
| Nelson, MV | 1 |
| Krenzelok, EP | 1 |
| Lesar, T | 1 |
| Romisher, S | 1 |
| Felter, R | 1 |
| Dougherty, J | 1 |
2 trials available for diphenhydramine and Dystonia
| Article | Year |
|---|---|
Antihistaminics in idiopathic dystonia.
Topics: Adult; Atropine; Benztropine; Chlorpheniramine; Cholinergic Antagonists; Diphenhydramine; Double-Bli | 1996 |
Beneficial effects of diphenhydramine in dystonia.
Topics: Adolescent; Adult; Aged; Child; Diphenhydramine; Double-Blind Method; Dystonia; Female; Histamine H1 | 1999 |
31 other studies available for diphenhydramine and Dystonia
| Article | Year |
|---|---|
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Diphenhydramine induced acute dystonia: a case report.
Topics: Diphenhydramine; Dystonia; Female; Humans; Hypersensitivity | 2022 |
Acute masseter dystonia in a pediatric patient receiving aripiprazole and methylphenidate following induction of general anesthesia.
Topics: Anesthesia, General; Antipsychotic Agents; Appendectomy; Aripiprazole; Central Nervous System Stimul | 2017 |
Prochlorperazine-Induced Hemidystonia Mimicking Acute Stroke.
Topics: Adult; Diphenhydramine; Dystonia; Emergency Medicine; Female; Humans; Hyperemesis Gravidarum; Infusi | 2015 |
Acute dystonic reaction in a patient with Parkinson's disease after diphenhydramine withdrawal.
Topics: Anesthetics, Local; Diphenhydramine; Dystonia; Female; Humans; Middle Aged; Parkinson Disease | 2017 |
Atypical laryngeal dystonia caused by an antiemetic.
Topics: Adult; Antiemetics; Aphonia; Diphenhydramine; Dystonia; Emetics; Female; Humans; Prochlorperazine | 2004 |
A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis.
Topics: Adolescent; Antiemetics; Diphenhydramine; Dopamine Antagonists; Dystonia; Female; Fundoplication; Hi | 2006 |
Drug-induced acute dystonic reactions in children. Alternatives to diphenhydramine therapy.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Child; Child, Preschool; Creatine Kinase; | 1984 |
Extended therapy for acute dystonic reactions.
Topics: Acute Disease; Adult; Benztropine; Biperiden; Diphenhydramine; Dystonia; Female; Humans; Jaw; Male; | 1984 |
Decorticate posture following 'cardiac cocktail': a transient complication of sedation for catheterization.
Topics: Cardiac Catheterization; Child, Preschool; Chlorpromazine; Diphenhydramine; Drug Combinations; Dysto | 1982 |
Acute dystonia secondary to illicit phenothiazine usage: a report of two cases.
Topics: Adult; Diphenhydramine; Dystonia; Humans; Male; Phenothiazines; Substance-Related Disorders | 1981 |
Simulated dystonia.
Topics: Adult; Diphenhydramine; Dystonia; Emergency Service, Hospital; Female; Humans; Malingering; Substanc | 1980 |
Dystonic reaction following recommended use of a cold syrup.
Topics: Benztropine; Child, Preschool; Diphenhydramine; Drug Combinations; Dystonia; Histamine H1 Antagonist | 1995 |
Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Halope | 1995 |
Diphenhydramine is effective in the treatment of idiopathic dystonia.
Topics: Adult; Diphenhydramine; Dystonia; Female; Humans; Male; Middle Aged | 1995 |
Dystonic-like reaction following cisapride therapy.
Topics: Adult; Cisapride; Diphenhydramine; Dystonia; Female; Gastroesophageal Reflux; Humans; Parasympathomi | 1995 |
Phenytoin-induced movement disorder. Unilateral presentation in a child and response to diphenhydramine.
Topics: Child, Preschool; Diphenhydramine; Dyskinesia, Drug-Induced; Dystonia; Facial Muscles; Female; Hemip | 1994 |
Drug-induced dystonia in a patient with C4 quadriplegia. Case report.
Topics: Adolescent; Diphenhydramine; Dystonia; Humans; Male; Prochlorperazine; Quadriplegia; Tongue | 1993 |
Dystonic reaction associated with dextromethorphan ingestion in a toddler.
Topics: Antidotes; Antitussive Agents; Ataxia; Child, Preschool; Dextromethorphan; Diphenhydramine; Dystonia | 1997 |
Cocaine-associated dystonic reaction.
Topics: Adult; Antiparkinson Agents; Cocaine; Diphenhydramine; Dystonia; Emergencies; Humans; Male | 1997 |
Acute laryngeal dystonia related to neuroleptic agents.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Diphenhydramine; Dystonia; Female; Halo | 1999 |
Nefazadone-induced acute dystonic reaction.
Topics: Antidepressive Agents, Second-Generation; Antiemetics; Benztropine; Diphenhydramine; Drug Interactio | 1999 |
Emergency! Prochlorperazine-induced dystonia.
Topics: Adolescent; Animals; Antiemetics; Diagnosis, Differential; Diphenhydramine; Dystonia; Emergencies; F | 1999 |
Treatment of drug-induced dystonic reactions.
Topics: Adolescent; Adult; Benztropine; Diphenhydramine; Dystonia; Female; Haloperidol; Humans; Injections, | 1979 |
Treatment of acute phenothiazine reaction.
Topics: Adult; Child; Diphenhydramine; Dystonia; Humans; Male; Phenothiazines | 1979 |
Erythromycin-related dystonic reaction.
Topics: Adult; Benztropine; Diphenhydramine; Dystonia; Erythromycin Ethylsuccinate; Humans; Male | 1992 |
Diphenhydramine and acute dystonia.
Topics: Aged; Diphenhydramine; Dystonia; Female; Humans | 1989 |
Diphenhydramine-induced dystonia.
Topics: Adult; Diphenhydramine; Dystonia; Female; Humans | 1989 |
Paroxysms, obtundation in a healthy toddler.
Topics: Child, Preschool; Diphenhydramine; Dystonia; Humans; Male; Phenothiazines | 1986 |
Acute dystonia from etoposide.
Topics: Child; Diphenhydramine; Dystonia; Etoposide; Humans; Leukemia, Lymphoid; Male | 1988 |
Unusual treatment response of a severe dystonia to diphenhydramine.
Topics: Adult; Benztropine; Delayed-Action Preparations; Diphenhydramine; Dystonia; Fluphenazine; Humans; Ma | 1987 |
Tagamet-induced acute dystonia.
Topics: Adult; Cimetidine; Diphenhydramine; Dystonia; Emergencies; Female; Humans | 1987 |