diphenhydramine has been researched along with Drug Hypersensitivity in 113 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dexamethasone withdrawal from W3 to W12 in early stage breast cancer patients treated with weekly paclitaxel is feasible." | 9.30 | The feasibility of dexamethasone omission in weekly paclitaxel treatment for breast cancer patients. ( Castro, SN; de Castro Baccarin, AL; de Iracema Gomes Cubero, D; Del Giglio, A; Irene, MN; Luz, AS; Móz, LES; Sordi, R, 2019) |
| "Sub-Tenon's space delivery of topotecan in a fibrin sealant was used as an adjunct to laser therapy for small retinoblastoma tumors in 25 children (77 injections)." | 7.81 | Hypersensitivity to sub-Tenon's topotecan in fibrin adhesive in patients with retinoblastoma. ( Astudillo, PP; Chan, HS; Durairaj, P; Gallie, BL; Héon, E, 2015) |
| "Vemurafenib and dabrafenib are both orally bioavailable small molecule agents that block mitogen activated protein kinase signalling in patients with melanoma and BRAF(V600E) mutation." | 7.81 | Successful desensitization protocol for hypersensitivity reaction probably caused by dabrafenib in a patient with metastatic melanoma. ( Abu-Amna, M; Bar-Sela, G; Hadad, S; Haim, N; Shahar, E, 2015) |
| "A chart review of the breast cancer SLN database was performed; it included 2392 sequential patients who underwent SLN biopsy involving isosulfan blue dye at Memorial Sloan-Kettering Cancer Center from September 12, 1996, to August 17, 2000." | 5.31 | Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer. ( Borgen, PI; Cody, HS; Fey, J; Gemignani, M; Heerdt, AS; Montgomery, LL; Petrek, J; Port, E; Thorne, AC; Van Zee, KJ, 2002) |
| "Dexamethasone withdrawal from W3 to W12 in early stage breast cancer patients treated with weekly paclitaxel is feasible." | 5.30 | The feasibility of dexamethasone omission in weekly paclitaxel treatment for breast cancer patients. ( Castro, SN; de Castro Baccarin, AL; de Iracema Gomes Cubero, D; Del Giglio, A; Irene, MN; Luz, AS; Móz, LES; Sordi, R, 2019) |
| " The diphenhydramine median pain score was 55 mm, compared with 12." | 5.08 | Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia. ( Bartfield, JM; Jandreau, SW; Raccio-Robak, N, 1998) |
| "Background Carboplatin-based chemotherapy offers high response rates and improved overall survival for women with epithelial ovarian cancer, but its use is limited by the occurrence of hypersensitivity reactions." | 3.88 | Prevention of carboplatin-induced hypersensitivity reactions in women with ovarian cancer. ( Bulter, M; Deghan Manshadi, S; Jerzak, KJ; Mackay, HJ; Maganti, M; McCuaig, JM; Ng, P; Oza, A, 2018) |
| "Paclitaxel-based chemotherapy continues to be an integral component of breast cancer treatment." | 3.81 | Stopping paclitaxel premedication after two doses in patients not experiencing a previous infusion hypersensitivity reaction. ( Berger, MJ; Layman, R; Lustberg, MB; Macrae, E; Mrozek, E; Phillips, G; Ramaswamy, B; Shapiro, CL; Shaver, K; Vargo, C; Vincent, M; Wesolowski, R, 2015) |
| "Sub-Tenon's space delivery of topotecan in a fibrin sealant was used as an adjunct to laser therapy for small retinoblastoma tumors in 25 children (77 injections)." | 3.81 | Hypersensitivity to sub-Tenon's topotecan in fibrin adhesive in patients with retinoblastoma. ( Astudillo, PP; Chan, HS; Durairaj, P; Gallie, BL; Héon, E, 2015) |
| "Vemurafenib and dabrafenib are both orally bioavailable small molecule agents that block mitogen activated protein kinase signalling in patients with melanoma and BRAF(V600E) mutation." | 3.81 | Successful desensitization protocol for hypersensitivity reaction probably caused by dabrafenib in a patient with metastatic melanoma. ( Abu-Amna, M; Bar-Sela, G; Hadad, S; Haim, N; Shahar, E, 2015) |
| "A 73-year-old Caucasian woman with metastatic bladder cancer developed hives, itching, difficulty in breathing, and general ill-feeling during the first 10 min of her first infusion of paclitaxel." | 3.74 | Cross-reactivity between paclitaxel and hazelnut: a case report. ( Bander, R; Bukacel, DG; Ibrahim, RB, 2007) |
| "Carboplatin is the drug of choice for the treatment of nonresectable astrocytomas in children, but patients who are intolerant may require cranial irradiation which is associated with significant morbidity." | 3.69 | Successful desensitization to carboplatin in patients with systemic hypersensitivity reactions. ( Broome, CB; Friedman, HS; Schiff, RI, 1996) |
| "A 52-year-old man developed contact and photoallergic dermatitis caused by diphenhydramine hydrochloride as well as contact dermatitis from paraphenylenediamine." | 3.65 | Allergic and photoallergic dermatitis from diphenhydramine. ( Horio, T, 1976) |
| "Five patients with recurrent ovarian cancer who had a previous documented hypersensitivity reaction to carboplatin and a good clinical indication for continuing treatment with platinum were retreated following cisplatin desensitisation." | 2.71 | Carboplatin hypersensitivity reactions: re-treatment with cisplatin desensitisation. ( Friedlander, M; Jones, R; Ryan, M, 2003) |
| "Docetaxel is active for metastatic breast cancer." | 2.68 | Phase II and pharmacologic study of docetaxel as initial chemotherapy for metastatic breast cancer. ( Balmaceda, C; Baselga, J; Bruno, R; Crown, JP; Currie, V; Freilich, R; Gilewski, TA; Gollub, M; Hakes, TB; Hudis, CA; Lebwohl, DE; Norton, L; Raptis, G; Robles, M; Seidman, AD, 1996) |
| "The present study was conducted to compare the pharmacokinetics and pharmacodynamics (PD) of paclitaxel between Phase I trials of 3- and 24-h infusions and to determine the most informative pharmacokinetic parameter to describe the PD." | 2.68 | Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion. ( Miyata, Y; Nakanomyo, H; Nishiwaki, Y; Ohtsu, T; Saijo, N; Sasaki, Y; Tamura, T, 1995) |
| "Anaphylactoid reactions are nonimmune mediated, but histamine release and other mediators produce a clinical presentation indistinguishable from anaphylaxis." | 2.39 | Systemic anaphylactoid reactions to iodinated contrast media during cardiac catheterization procedures: guidelines for prevention, diagnosis, and treatment. Laboratory Performance Standards Committee of the Society for Cardiac Angiography and Intervention ( Chambers, CE; Goss, JE; Heupler, FA, 1995) |
| "Cetirizine appears to be a viable substitute for diphenhydramine for the prevention of infusions reactions with cetuximab, paclitaxel, and rituximab infusions in adults." | 1.51 | Cetirizine versus diphenhydramine in the prevention of chemotherapy-related hypersensitivity reactions. ( Durham, CG; Foster, J; Herrington, JD; Sager, L; Thotakura, D, 2019) |
| "The FDA's adverse event reporting system, AERS, with optimized data mining tools is useful to authorize potential associations between platinum agents and hypersensitivity reactions." | 1.37 | Platinum agent-induced hypersensitivity reactions: data mining of the public version of the FDA adverse event reporting system, AERS. ( Kadoyama, K; Niijima, S; Okuno, Y; Sakaeda, T; Seki, K; Shiraishi, Y; Yabuuchi, H, 2011) |
| "In 115/122 breast cancer patients not hypersensitive to initial PTX treatment, 20 mg dexamethasone (DXM) doses were tapered by 2." | 1.33 | Tapering and discontinuation of glucocorticoid prophylaxis during prolonged weekly to biweekly paclitaxel administration. ( Adamson, B; Braverman, AS; McManus, M; Pierre, S; Rao, S; Salvatti, ME, 2005) |
| "We report a patient with metastatic colon cancer who developed a hypersensitivity reaction to oxaliplatin during the sixth cycle of combination chemotherapy with oxaliplatin, high-dose 5-fluorouracil and leucovorin." | 1.32 | Hypersensitivity reactions to oxaliplatin: a case report and the success of a continuous infusional desensitization schedule. ( Chang, MC; Chang, YF; Hsieh, RK; Huang, MJ; Lim, KH; Lin, HC; Lin, J; Su, YW, 2004) |
| "A chart review of the breast cancer SLN database was performed; it included 2392 sequential patients who underwent SLN biopsy involving isosulfan blue dye at Memorial Sloan-Kettering Cancer Center from September 12, 1996, to August 17, 2000." | 1.31 | Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer. ( Borgen, PI; Cody, HS; Fey, J; Gemignani, M; Heerdt, AS; Montgomery, LL; Petrek, J; Port, E; Thorne, AC; Van Zee, KJ, 2002) |
| " When HSR was observed administration of paclitaxel was temporally stopped and before the re-challenge additional intravenous dosage of hydrocortisone (200-500 mg) and diphenhydramine (25 mg) was given." | 1.31 | [Paclitaxel hypersensitivity reactions in patients with advanced ovarian carcinoma]. ( Emerich, J; Kobierski, J; Majdak, E; Mielcarek, P, 2002) |
| "Diphenhydramine is an adequate alternative of local anesthetics in patients with history of hypersensitivity to local anesthetics." | 1.31 | [Diphenhydramine is useful in a parturient with hypersensitivity to local anesthetics to manage her delivery]. ( Hiruta, M; Horikawa, Y; Kawakami, T; Mitsuhata, H; Saito, J; Seo, N, 2002) |
| "Diphenhydramine has been suggested as an alternative local anesthetic agent for patients claiming allergy to local anesthetics." | 1.30 | Local anesthetic efficacy for oral surgery: Comparison of diphenhydramine and prilocaine. ( Guler, N; Sumer, M; Uckan, S; Ungor, M, 1998) |
| "Chronic urticaria is plainly visible in clinical presentation but is more elusive in diagnosis and treatment." | 1.27 | Urticaria--a challenge in diagnosis and treatment. ( Wagner, WO, 1988) |
| "Cimetidine has recently proved useful in the prophylaxis of certain allergic and other histamine-mediated reactions." | 1.26 | Cimetidine (Tagamet) combined with steroids and H1 antihistamines for the prevention of serious radiographic contrast material reactions. ( Bloom, FL; Myers, GE, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (39.82) | 18.7374 |
| 1990's | 21 (18.58) | 18.2507 |
| 2000's | 24 (21.24) | 29.6817 |
| 2010's | 23 (20.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suh, J | 1 |
| Slawski, BR | 1 |
| Long, AA | 1 |
| Guidon, AC | 1 |
| Chamorro-Pareja, N | 1 |
| Carrillo-Martin, I | 2 |
| Haehn, DA | 1 |
| Gonzalez-Estrada, A | 2 |
| Kuhn, J | 1 |
| Noda, C | 1 |
| Massey, GV | 1 |
| Bina, B | 1 |
| Hersh, EV | 1 |
| Hilario, M | 1 |
| Alvarez, K | 1 |
| McLaughlin, B | 1 |
| Ngo, SY | 1 |
| Rabbat, JC | 1 |
| de Castro Baccarin, AL | 1 |
| Irene, MN | 1 |
| de Iracema Gomes Cubero, D | 1 |
| Luz, AS | 1 |
| Castro, SN | 1 |
| Sordi, R | 1 |
| Móz, LES | 1 |
| Del Giglio, A | 1 |
| Durham, CG | 1 |
| Thotakura, D | 1 |
| Sager, L | 1 |
| Foster, J | 1 |
| Herrington, JD | 1 |
| Rodriguez-Nava, G | 1 |
| Kesler, AM | 1 |
| Lightner, DD | 1 |
| De Braganca, K | 1 |
| Gilheeney, SW | 1 |
| Khakoo, Y | 1 |
| Kramer, K | 1 |
| Balas, M | 1 |
| Logsdon, S | 1 |
| Ramirez-Avila, L | 1 |
| Castells, M | 1 |
| Dioun, A | 1 |
| Toderian, AB | 1 |
| Lawson, ML | 1 |
| Auerbach, M | 2 |
| Macdougall, IC | 1 |
| Berger, MJ | 1 |
| Vargo, C | 1 |
| Vincent, M | 1 |
| Shaver, K | 1 |
| Phillips, G | 1 |
| Layman, R | 1 |
| Macrae, E | 1 |
| Mrozek, E | 1 |
| Ramaswamy, B | 1 |
| Wesolowski, R | 1 |
| Shapiro, CL | 1 |
| Lustberg, MB | 1 |
| Astudillo, PP | 1 |
| Durairaj, P | 1 |
| Chan, HS | 1 |
| Héon, E | 1 |
| Gallie, BL | 1 |
| Bar-Sela, G | 1 |
| Abu-Amna, M | 1 |
| Hadad, S | 1 |
| Haim, N | 1 |
| Shahar, E | 1 |
| Mervak, BM | 1 |
| Davenport, MS | 2 |
| Ellis, JH | 3 |
| Cohan, RH | 3 |
| Gupta, A | 1 |
| Harris, S | 1 |
| Naina, H | 1 |
| DeLoughery, TG | 1 |
| Jerzak, KJ | 1 |
| Deghan Manshadi, S | 1 |
| Ng, P | 1 |
| Maganti, M | 1 |
| McCuaig, JM | 1 |
| Bulter, M | 1 |
| Oza, A | 1 |
| Mackay, HJ | 1 |
| Wang, CL | 1 |
| Caoili, EM | 2 |
| Wang, G | 1 |
| Francis, IR | 1 |
| Lasser, EC | 1 |
| Metz, KA | 1 |
| Johnson, T | 1 |
| Hershey, GK | 1 |
| Lierl, MB | 1 |
| Seidu, L | 1 |
| Burns, K | 1 |
| Assa'ad, A | 1 |
| DEAN, G | 1 |
| Sheth, SS | 1 |
| Posner, MA | 1 |
| Siu, SW | 1 |
| Chan, WL | 1 |
| Liu, KY | 1 |
| Choy, TS | 1 |
| Leung, TW | 1 |
| Au, KH | 1 |
| Sakaeda, T | 1 |
| Kadoyama, K | 1 |
| Yabuuchi, H | 1 |
| Niijima, S | 1 |
| Seki, K | 1 |
| Shiraishi, Y | 1 |
| Okuno, Y | 1 |
| Codreanu, I | 1 |
| Dasanu, CA | 1 |
| Weinstein, GS | 1 |
| Divgi, C | 1 |
| Montgomery, LL | 1 |
| Thorne, AC | 1 |
| Van Zee, KJ | 1 |
| Fey, J | 1 |
| Heerdt, AS | 1 |
| Gemignani, M | 1 |
| Port, E | 1 |
| Petrek, J | 1 |
| Cody, HS | 1 |
| Borgen, PI | 1 |
| Quock, J | 1 |
| Dea, G | 1 |
| Tanaka, M | 1 |
| Gandara, D | 1 |
| Lara, P | 1 |
| Lau, D | 1 |
| Jones, R | 1 |
| Ryan, M | 1 |
| Friedlander, M | 1 |
| Thomas, RR | 1 |
| Quinn, MG | 1 |
| Schuler, B | 1 |
| Grem, JL | 1 |
| Kobierski, J | 1 |
| Majdak, E | 1 |
| Mielcarek, P | 1 |
| Emerich, J | 1 |
| POLIAKOFF, H | 1 |
| JENSEN, K | 1 |
| TRINKNER, RL | 1 |
| PERKINS, HA | 1 |
| MEYER, RA | 1 |
| JAKUBOWSKI, W | 1 |
| CAMPOLATTARO, JP | 1 |
| HAROLDSON, JH | 1 |
| WELBORN, JF | 1 |
| KANE, JP | 1 |
| PORSIO, A | 1 |
| BORGIA, M | 1 |
| TURCOTTE, JG | 1 |
| KRAFT, RO | 1 |
| FRY, WJ | 1 |
| GRABER, CD | 1 |
| FRED, HL | 1 |
| LAUDERDALE, WH | 1 |
| Lim, KH | 1 |
| Huang, MJ | 1 |
| Lin, HC | 1 |
| Su, YW | 1 |
| Chang, YF | 1 |
| Lin, J | 1 |
| Chang, MC | 1 |
| Hsieh, RK | 1 |
| Braverman, AS | 1 |
| Rao, S | 1 |
| Salvatti, ME | 1 |
| Adamson, B | 1 |
| McManus, M | 1 |
| Pierre, S | 1 |
| Saadeh, CE | 1 |
| Srkalovic, G | 1 |
| Touma Fernández, A | 1 |
| Ortiz Cortés, J | 1 |
| Díaz Fernández, F | 1 |
| Poncela García, M | 1 |
| Rodríguez Prieto, M | 1 |
| Pera Rojas, C | 1 |
| Hall, M | 1 |
| Hagemann, TM | 1 |
| Steffensmeier, AC | 1 |
| Azar, AE | 1 |
| Fuller, JJ | 1 |
| Muller, BA | 1 |
| Russell, SR | 1 |
| Bukacel, DG | 1 |
| Bander, R | 1 |
| Ibrahim, RB | 1 |
| Sasada, S | 1 |
| Hirashima, T | 1 |
| Nakamura, Y | 1 |
| Takimoto, T | 1 |
| Furukawa, M | 1 |
| Kobayashi, M | 1 |
| Nitta, T | 1 |
| Matsui, K | 1 |
| Kawase, I | 1 |
| Kim, KH | 1 |
| Decker, C | 1 |
| Burton, BK | 1 |
| Kononiuk, GIa | 1 |
| Krasiĭ, PA | 1 |
| Novozhilov, VA | 1 |
| Nizhnikova, KM | 1 |
| Odom, LF | 1 |
| Gordon, EM | 1 |
| Myers, GE | 1 |
| Bloom, FL | 1 |
| Delaney, WV | 1 |
| Becker, DE | 1 |
| Goss, JE | 1 |
| Chambers, CE | 1 |
| Heupler, FA | 1 |
| Manhart, AR | 1 |
| Egwiekhor, OA | 1 |
| Jahns, BE | 1 |
| Rynn, KO | 1 |
| Hainsworth, JD | 1 |
| Greco, FA | 1 |
| Peereboom, DM | 1 |
| Donehower, RC | 1 |
| Eisenhauer, EA | 1 |
| McGuire, WP | 1 |
| Onetto, N | 1 |
| Hubbard, JL | 1 |
| Piccart, M | 1 |
| Gianni, L | 1 |
| Rowinsky, EK | 1 |
| Dire, DJ | 1 |
| Hogan, DE | 1 |
| Lossef, SV | 1 |
| Barth, KH | 1 |
| Broome, CB | 1 |
| Schiff, RI | 1 |
| Friedman, HS | 1 |
| Hudis, CA | 1 |
| Seidman, AD | 1 |
| Crown, JP | 1 |
| Balmaceda, C | 1 |
| Freilich, R | 1 |
| Gilewski, TA | 1 |
| Hakes, TB | 1 |
| Currie, V | 1 |
| Lebwohl, DE | 1 |
| Baselga, J | 1 |
| Raptis, G | 1 |
| Gollub, M | 1 |
| Robles, M | 1 |
| Bruno, R | 1 |
| Norton, L | 1 |
| Green, SM | 1 |
| Marra, CA | 1 |
| Shalansky, KF | 1 |
| Smith, RE | 1 |
| Townsend, GE | 1 |
| Berry, BR | 1 |
| Bowen, T | 1 |
| Bookman, MA | 1 |
| Kloth, DD | 1 |
| Kover, PE | 1 |
| Smolinski, S | 1 |
| Ozols, RF | 1 |
| Renz, C | 1 |
| Lynch, J | 1 |
| Thurn, J | 1 |
| Moss, J | 1 |
| Uckan, S | 1 |
| Guler, N | 1 |
| Sumer, M | 1 |
| Ungor, M | 1 |
| Ohtsu, T | 1 |
| Sasaki, Y | 1 |
| Tamura, T | 1 |
| Miyata, Y | 1 |
| Nakanomyo, H | 1 |
| Nishiwaki, Y | 1 |
| Saijo, N | 1 |
| Bartfield, JM | 1 |
| Jandreau, SW | 1 |
| Raccio-Robak, N | 1 |
| Markman, M | 2 |
| Kennedy, A | 2 |
| Webster, K | 2 |
| Peterson, G | 2 |
| Kulp, B | 2 |
| Belinson, J | 2 |
| Myers, JS | 1 |
| Kearney, K | 1 |
| Moon, C | 1 |
| Verschraegen, CF | 1 |
| Bevers, M | 1 |
| Freedman, R | 1 |
| Kudelka, AP | 1 |
| Kavanagh, JJ | 1 |
| Brown, DL | 1 |
| Login, IS | 1 |
| Borish, L | 1 |
| Powers, PL | 1 |
| Kwon, JS | 1 |
| Elit, L | 1 |
| Finn, M | 1 |
| Hirte, H | 1 |
| Mazurka, J | 1 |
| Moens, F | 1 |
| Trim, K | 1 |
| Horikawa, Y | 1 |
| Mitsuhata, H | 1 |
| Saito, J | 1 |
| Kawakami, T | 1 |
| Hiruta, M | 1 |
| Seo, N | 1 |
| Wiesenfeld, M | 1 |
| Reinders, E | 1 |
| Corder, M | 1 |
| Yoo, TJ | 1 |
| Dietz, B | 1 |
| Lovett, J | 1 |
| Roberts, EW | 1 |
| Loveless, H | 1 |
| Soskin, IaM | 1 |
| Kruglikova, LI | 1 |
| Millbern, SM | 1 |
| Bell, SD | 1 |
| Verrill, PJ | 1 |
| Horio, T | 1 |
| Glauda, NM | 1 |
| Henefer, EP | 1 |
| Super, S | 1 |
| Schatz, M | 2 |
| Patterson, R | 1 |
| O'Rourke, J | 1 |
| Nickelsen, J | 1 |
| Northup, C | 1 |
| Obeid, AI | 1 |
| Johnson, L | 1 |
| Potts, J | 1 |
| Mookherjee, S | 1 |
| Eich, RH | 1 |
| Weiner, AL | 1 |
| Bulakhova, EK | 1 |
| Agafonova, IA | 1 |
| Mizuno, H | 1 |
| Kawamura, Y | 1 |
| Iwase, N | 1 |
| Ohno, H | 1 |
| Kellie, SJ | 1 |
| Crist, WM | 1 |
| Pui, CH | 1 |
| Crone, ME | 1 |
| Fairclough, DL | 1 |
| Rodman, JH | 1 |
| Rivera, GK | 1 |
| Loeb, JA | 1 |
| Herold, KC | 1 |
| Barton, KP | 1 |
| Robinson, LE | 1 |
| Jaspan, JB | 1 |
| Wiernik, PH | 1 |
| Schwartz, EL | 1 |
| Einzig, A | 1 |
| Strauman, JJ | 1 |
| Lipton, RB | 1 |
| Dutcher, JP | 1 |
| Wagner, WO | 1 |
| Fung, DL | 1 |
| Hayes, FA | 1 |
| Abromowitch, M | 1 |
| Green, AA | 1 |
| Gibbons, RB | 1 |
| Lindauer, JA | 1 |
| Shelley, WB | 1 |
| Bennett, RG | 1 |
| Davenport, PM | 1 |
| Wilhelm, RE | 1 |
| Falleroni, AE | 1 |
| Pankratov, VG | 1 |
| Iagovdik, NZ | 1 |
| Komov, OP | 1 |
| Timofeeva, LP | 1 |
| Sheffer, AL | 1 |
| Gates, DF | 1 |
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| Bourne, RB | 1 |
| Daughters, D | 1 |
| Zackheim, H | 1 |
| Maibach, H | 1 |
| Holder, LE | 1 |
| Haber, K | 1 |
| Miller, R | 1 |
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| Schwartz, HJ | 1 |
| Fidel', VG | 1 |
| Munsey, WF | 1 |
| Kopp, WL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Olanzapine, Netupitant and Palonosetron in Controlling Nausea and Vomiting Associated With Highly Emetogenic Chemotherapy in Patients With Breast Cancer[NCT04669132] | Phase 2 | 50 participants (Actual) | Interventional | 2020-12-17 | Completed | ||
| Feasibility of a Randomized Controlled Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel[NCT04237090] | Phase 3 | 27 participants (Actual) | Interventional | 2020-02-14 | Completed | ||
| Prevention of Iron Deficiency Anemia Post-delivery (PRIORITY Trial): A Randomized Controlled Trial of the Global Network for Women's and Children's Health Research[NCT05590260] | Phase 3 | 4,800 participants (Anticipated) | Interventional | 2023-05-30 | Recruiting | ||
| An Open-label Randomized Clinical Trial to Compare the Toxicities and Efficacy of Pharmacokinetically-guided and BSA Fixed Dosing Strategy of Docetaxel and Paclitaxel in Chinese Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma, and Breast Cancer Patie[NCT01891123] | 300 participants (Anticipated) | Interventional | 2013-06-30 | Recruiting | |||
| A Clinical Experience Trial to Detect the Plasma Paclitaxel Drug Concentration in Chinese Non -Small Cell Lung Cancer (NSCLC) Patients Treated With a Paclitaxel Plus Carboplatin (TC) Regimens, and Explore Individualized Treatment Using Pharmacokinetically[NCT02737709] | Phase 2 | 51 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to The study have difficulty in recruiting subjectes) | ||
| Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534] | 29 participants (Actual) | Observational | 2015-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for diphenhydramine and Drug Hypersensitivity
| Article | Year |
|---|---|
True Allergy to Amide Local Anesthetics: A Review and Case Presentation.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Contraindications, Drug; Diphenhydramine; Drug Hypers | 2018 |
Safety of intravenous iron formulations: facts and folklore.
Topics: Administration, Intravenous; Anaphylaxis; Anti-Allergic Agents; Diphenhydramine; Drug Hypersensitivi | 2014 |
Hypersensitivity and idiosyncratic reactions to oxaliplatin.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Cim | 2003 |
Management of immediate allergic reactions.
Topics: Adrenergic Agonists; Anaphylaxis; Anti-Allergic Agents; Dental Care; Dental Offices; Diphenhydramine | 1995 |
Systemic anaphylactoid reactions to iodinated contrast media during cardiac catheterization procedures: guidelines for prevention, diagnosis, and treatment. Laboratory Performance Standards Committee of the Society for Cardiac Angiography and Intervention
Topics: Anaphylaxis; Cardiac Catheterization; Combined Modality Therapy; Coronary Angiography; Critical Care | 1995 |
What is the role of diphenhydramine in local anesthesia?
Topics: Anesthesia, Local; Anesthetics, Local; Diphenhydramine; Drug Hypersensitivity; Emergency Medical Ser | 1996 |
Anaphylactic and anaphylactoid reactions due to anesthetic agents.
Topics: Anaphylaxis; Anesthesia, General; Anesthesia, Local; Anesthetics; Diphenhydramine; Drug Hypersensiti | 1986 |
Treatment of allergic emergencies.
Topics: Aminophylline; Anaphylaxis; Antigen-Antibody Reactions; Bronchial Spasm; Diphenhydramine; Drug Hyper | 1968 |
11 trials available for diphenhydramine and Drug Hypersensitivity
| Article | Year |
|---|---|
The feasibility of dexamethasone omission in weekly paclitaxel treatment for breast cancer patients.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; D | 2019 |
Carboplatin hypersensitivity reactions: re-treatment with cisplatin desensitisation.
Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Dexamethasone; Diphenhydramine; Drug Hypersensitivity | 2003 |
Paclitaxel administered by 1-hour infusion. Preliminary results of a phase I/II trial comparing two schedules.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cimetidine; Dexamethasone; Diphenhydr | 1994 |
Successful re-treatment with taxol after major hypersensitivity reactions.
Topics: Aged; Dexamethasone; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Hista | 1993 |
Double-blinded comparison of diphenhydramine versus lidocaine as a local anesthetic.
Topics: Adult; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Humans; Inje | 1993 |
Phase II and pharmacologic study of docetaxel as initial chemotherapy for metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cimetidine; Dexamethasone; Diphenh | 1996 |
Short-course intravenous prophylaxis for paclitaxel-related hypersensitivity reactions.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphen | 1997 |
Histamine release during rapid vancomycin administration.
Topics: Anti-Bacterial Agents; Cimetidine; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Exan | 1998 |
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re | 1995 |
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re | 1995 |
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re | 1995 |
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re | 1995 |
Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.
Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Diphenhydramine; Double-Blind Method; Drug Combinations; | 1998 |
Paclitaxel-associated hypersensitivity reactions: experience of the gynecologic oncology program of the Cleveland Clinic Cancer Center.
Topics: Adult; Aged; Aged, 80 and over; Clinical Protocols; Desensitization, Immunologic; Dexamethasone; Dip | 2000 |
94 other studies available for diphenhydramine and Drug Hypersensitivity
| Article | Year |
|---|---|
Rituximab desensitization in two patients with muscle-specific kinase myasthenia gravis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Autoantibodies; Desensitiz | 2019 |
Documented exogenous progesterone hypersensitivity related to the use of combined oral contraceptive.
Topics: Adolescent; Anti-Allergic Agents; Contraceptives, Oral, Combined; Diphenhydramine; Drug Hypersensiti | 2019 |
Successful multi-modal immune tolerance induction for factor IX deficiency with inhibitors and allergic reactions.
Topics: Anaphylaxis; Antibodies, Blocking; Child; Combined Modality Therapy; Desensitization, Immunologic; D | 2018 |
Systemic IgE-mediated hypersensitivity reaction to topical polymyxin B.
Topics: Anti-Bacterial Agents; Bacitracin; Child; Diphenhydramine; Drug Combinations; Drug Hypersensitivity; | 2019 |
Cetirizine versus diphenhydramine in the prevention of chemotherapy-related hypersensitivity reactions.
Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Agents, Phytogenic; Cetirizine; Cetuximab | 2019 |
Gadolinium-induced anaphylaxis with positive skin test results.
Topics: Adult; Allergens; Anaphylaxis; Angioedema; Contrast Media; Diphenhydramine; Drug Hypersensitivity; F | 2019 |
A case of mannitol hypersensitivity.
Topics: Anaphylaxis; Diphenhydramine; Drug Hypersensitivity; Fatal Outcome; Histamine H1 Antagonists; Humans | 2013 |
Successful rifampin desensitization in a pediatric patient with latent tuberculosis.
Topics: Child; Clinical Protocols; Contraindications; Desensitization, Immunologic; Diphenhydramine; Drug Do | 2014 |
Use of antihistamines after serious allergic reaction to methimazole in pediatric Graves' disease.
Topics: Adolescent; Antithyroid Agents; Diphenhydramine; Dose-Response Relationship, Drug; Drug Administrati | 2014 |
Stopping paclitaxel premedication after two doses in patients not experiencing a previous infusion hypersensitivity reaction.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brea | 2015 |
Hypersensitivity to sub-Tenon's topotecan in fibrin adhesive in patients with retinoblastoma.
Topics: Anti-Allergic Agents; Antineoplastic Agents; Child, Preschool; Conjunctival Diseases; Diphenhydramin | 2015 |
Successful desensitization protocol for hypersensitivity reaction probably caused by dabrafenib in a patient with metastatic melanoma.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Brain Neoplasms; Desensitization, Immunologic; Dexa | 2015 |
Rates of Breakthrough Reactions in Inpatients at High Risk Receiving Premedication Before Contrast-Enhanced CT.
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Child; Ch | 2015 |
Perflutren-Induced Angioedema.
Topics: Aged; Angioedema; Contrast Media; Diphenhydramine; Drug Hypersensitivity; Echocardiography; Female; | 2015 |
Is low-molecular weight iron dextran really the most risky iron?--Unconvincing data from an unconvincing study.
Topics: Age Factors; Algorithms; Anaphylaxis; Chemistry, Pharmaceutical; Clinical Protocols; Diagnosis-Relat | 2016 |
Prevention of carboplatin-induced hypersensitivity reactions in women with ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2018 |
Frequency, outcome, and appropriateness of treatment of nonionic iodinated contrast media reactions.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Albuterol; Contr | 2008 |
Nonionic iodinated contrast media reactions.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Albuterol; Contr | 2009 |
Successful administration of cytarabine in a 16-month-old girl with acute myelogenous leukemia and cytarabine syndrome.
Topics: Cytarabine; Diphenhydramine; Drug Hypersensitivity; Female; Histamine Antagonists; Humans; Immunosup | 2009 |
Repeat contrast medium reactions in premedicated patients: frequency and severity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Diphenhydramine; Drug Hypersensitivity; | 2009 |
Benadryl treatment of penicillin allergy.
Topics: Diphenhydramine; Drug Hypersensitivity; Penicillins | 1947 |
Modified protocol for desensitization to glatiramer acetate.
Topics: Adult; Chemotherapy, Adjuvant; Clinical Protocols; Desensitization, Immunologic; Diphenhydramine; Dr | 2010 |
Re-challenging patients with oxaliplatin allergy: the successful use of a standardised pre-medication protocol in a single institute.
Topics: Adult; Aged; Anaphylaxis; Anesthetics, Local; Anti-Inflammatory Agents; Antineoplastic Agents; Color | 2011 |
Platinum agent-induced hypersensitivity reactions: data mining of the public version of the FDA adverse event reporting system, AERS.
Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents; Bayes Theorem; Carboplatin; Cisplati | 2011 |
Fluorodeoxyglucose-induced allergic reaction: a case report.
Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Carcinoma, Squamous Cell; Diphenhydramine; Drug Hype | 2013 |
Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer.
Topics: Anaphylaxis; Anesthesia; Breast Neoplasms; Coloring Agents; Cross Reactions; Databases, Factual; Dip | 2002 |
Premedication strategy for weekly paclitaxel.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cime | 2002 |
[Paclitaxel hypersensitivity reactions in patients with advanced ovarian carcinoma].
Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phyto | 2002 |
Rapid treatment of severe diabetic ketosis associated with severe insulin allergy.
Topics: Diabetes Complications; Diabetic Ketoacidosis; Diphenhydramine; Drug Hypersensitivity; Epinephrine; | 1958 |
[ALLERGIC SHOCK AFTER ORALLY ADMINISTERED PENICILLIN].
Topics: Anaphylaxis; Asthma; Bronchitis; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Hydrocortisone | 1964 |
SEVERE ACUTE FIBRINOGENOPENIA APPARENTLY CAUSED BY REACTION TO DRUGS.
Topics: Afibrinogenemia; Blood Coagulation Tests; Diatrizoate; Diphenhydramine; Diuretics; Drug Hypersensiti | 1964 |
USE OF TRIPELENNAMINE AND DIPHENHYDRAMINE AS LOCAL ANESTHETICS.
Topics: Anesthetics; Anesthetics, Local; Biomedical Research; Dental Care; Diphenhydramine; Drug Hypersensit | 1964 |
DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL) AS A LOCAL ANESTHETIC IN PROCAINE AND LIDOCAINE SENSITIVE PATIENTS.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics; Anesthetics, Local; Diphenhydramine; Drug Hypers | 1964 |
CONDUCTION ANESTHESIA USING DIPHENHYDRAMINE HYDROCHLORIDE.
Topics: Anesthesia; Anesthesia, Conduction; Diphenhydramine; Drug Hypersensitivity; Humans; Lidocaine; Pharm | 1964 |
[ON THE THERAPEUTIC POSSIBILITIES OF A NEW DRUG ASSOCIATION WITH ANTIALLERGIC AND ANTIEXUDATIVE ACTIVITY].
Topics: Aminocaproates; Aminocaproic Acid; Anti-Allergic Agents; Diphenhydramine; Drug Hypersensitivity; Dru | 1964 |
HEPARIN REACTIONS IN PATIENTS WITH VASCULAR DISEASE.
Topics: Anaphylaxis; Aortic Diseases; Diphenhydramine; Drug Hypersensitivity; Drug Therapy; Geriatrics; Hepa | 1965 |
SEROLOGICAL IDENTIFICATION OF DIPHENHYDRAMINE AS CAUSE OF ANAPHYLACTOID RESPONSE IN MAN.
Topics: Diphenhydramine; Drug Hypersensitivity; Hemagglutination; Hemagglutination Tests; Toxicology | 1964 |
Hypersensitivity reactions to oxaliplatin: a case report and the success of a continuous infusional desensitization schedule.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Desen | 2004 |
Tapering and discontinuation of glucocorticoid prophylaxis during prolonged weekly to biweekly paclitaxel administration.
Topics: Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Anti-Inflammatory Agents; Antineoplastic Agent | 2005 |
Acute hypersensitivity reaction to ferric gluconate in a premedicated patient.
Topics: Adult; Anemia, Hypochromic; Anti-Inflammatory Agents; Antipsychotic Agents; Dexamethasone; Diphenhyd | 2005 |
[Perioperative management of a patient allergic to multiple nondepolarizing neuromuscular blockers during treatment for cervical fracture and dislocation].
Topics: Adult; Anesthetics, General; Anti-Allergic Agents; Atracurium; Cervical Vertebrae; Contraindications | 2006 |
Successful desensitization to antithymocyte globulin in a child with aplastic anemia.
Topics: Anemia, Aplastic; Anti-Allergic Agents; Antilymphocyte Serum; Child, Preschool; Desensitization, Imm | 2006 |
Vitreous injections of pegaptanib sodium triggering allergic reactions.
Topics: Aged, 80 and over; Anaphylaxis; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascular | 2007 |
Cross-reactivity between paclitaxel and hazelnut: a case report.
Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Corylus; Cross Reactions; Diphenh | 2007 |
Preliminary experience with a modified premedication protocol that included intravenous diphenhydramine and calcium bromide for the prophylaxis of paclitaxel-related hypersensitivity reactions.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Bromides; Calcium Compounds; Carcinoma, Non-Small-Ce | 2007 |
Successful management of difficult infusion-associated reactions in a young patient with mucopolysaccharidosis type VI receiving recombinant human arylsulfatase B (galsulfase [Naglazyme]).
Topics: Child, Preschool; Diphenhydramine; Dose-Response Relationship, Drug; Drug Administration Schedule; D | 2008 |
[On cases of complications after administration of streptomycin].
Topics: Abortion, Veterinary; Animals; Cattle; Cattle Diseases; Diphenhydramine; Drug Hypersensitivity; Fema | 1966 |
[Resuscitation in acute allergic reactions to drugs].
Topics: Adult; Aged; Aminopyrine; Anaphylaxis; Angioedema; Dextrans; Diphenhydramine; Drug Hypersensitivity; | 1980 |
Acute monoblastic leukemia in infancy and early childhood: successful treatment with an epipodophyllotoxin.
Topics: Alopecia; Child; Child, Preschool; Diarrhea; Diphenhydramine; Drug Administration Schedule; Drug Hyp | 1984 |
Cimetidine (Tagamet) combined with steroids and H1 antihistamines for the prevention of serious radiographic contrast material reactions.
Topics: Adult; Cardiac Catheterization; Cimetidine; Contrast Media; Diphenhydramine; Drug Hypersensitivity; | 1981 |
Explained unexplained anisocoria.
Topics: Accommodation, Ocular; Adolescent; Diphenhydramine; Diplopia; Drug Hypersensitivity; Female; Humans; | 1980 |
Fatal anaphylactic shock to hyoscine and diphenhydramine: a doubtful diagnosis.
Topics: Anaphylaxis; Diphenhydramine; Drug Hypersensitivity; Drug Interactions; Fatal Outcome; Humans; Scopo | 1995 |
Severe delayed hypotensive reaction after Ethiodol lymphangiography despite premedication.
Topics: Adult; Diphenhydramine; Drug Hypersensitivity; Ethiodized Oil; Female; Humans; Hypersensitivity, Del | 1993 |
Successful desensitization to carboplatin in patients with systemic hypersensitivity reactions.
Topics: Anaphylaxis; Anti-Allergic Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Astrocytoma; Bra | 1996 |
Ampicillin-induced maculopapular versus urticarial rash.
Topics: Ampicillin; Anti-Allergic Agents; Diagnosis, Differential; Diphenhydramine; Drug Eruptions; Drug Hyp | 1996 |
Enoxaparin for unstable angina and ancrod for cardiac surgery following heparin allergy.
Topics: Aged; Ancrod; Angina, Unstable; Animals; Anticoagulants; Cattle; Coronary Artery Bypass; Diphenhydra | 1996 |
Local anesthetic efficacy for oral surgery: Comparison of diphenhydramine and prilocaine.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Dental Pulp; | 1998 |
An effective and more convenient drug regimen for prophylaxis against paclitaxel-associated hypersensitivity reactions.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Drug Ad | 1999 |
Emergency. Chemotherapy-induced hypersensitivity reaction.
Topics: Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Diphenhydramine; Drug Hypersensitivity; Eme | 2000 |
Use of docetaxel (Taxotere) in patients with paclitaxel (Taxol) hypersensitivity.
Topics: Adult; Antineoplastic Agents, Phytogenic; Carcinoma; Cimetidine; Cystadenocarcinoma; Dexamethasone; | 2000 |
An urticarial IgE-mediated reaction to interferon beta-1b.
Topics: Adult; Anti-Allergic Agents; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Hypersensitivit | 2001 |
A comparison of two prophylactic regimens for hypersensitivity reactions to paclitaxel.
Topics: Administration, Oral; Cohort Studies; Dexamethasone; Diphenhydramine; Drug Hypersensitivity; Female; | 2002 |
[Diphenhydramine is useful in a parturient with hypersensitivity to local anesthetics to manage her delivery].
Topics: Adult; Analgesia, Obstetrical; Anaphylaxis; Anesthetics, Local; Diphenhydramine; Drug Hypersensitivi | 2002 |
Successful re-treatment with cis-dichlorodiammineplatinum(II) after apparent allergic reactions.
Topics: Adult; Cisplatin; Diphenhydramine; Drug Hypersensitivity; Female; Histamine Release; Humans; Immunog | 1979 |
The utilization of diphenhydramine for production of local anesthesia: report of a case.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diphenhydramine; Drug Hypersensiti | 1979 |
[Acute epidermal necrolysis (Lyell's syndrome) after diagnostic curettage of the uterus].
Topics: Acute Disease; Aged; Dilatation and Curettage; Diphenhydramine; Drug Hypersensitivity; Female; Human | 1978 |
Prevention of anaphylaxis to contrast medium.
Topics: Angiocardiography; Angiography; Diatrizoate; Diatrizoate Meglumine; Diphenhydramine; Drug Hypersensi | 1979 |
Adverse reactions to local anaesthetics and vasoconstrictor drugs.
Topics: Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Arteriosclerosis; Blood Pressure; Coronary Dise | 1975 |
Allergic and photoallergic dermatitis from diphenhydramine.
Topics: Dermatitis, Contact; Diphenhydramine; Drug Hypersensitivity; Humans; Male; Middle Aged; Photosensiti | 1976 |
Nonfatal anaphylaxis caused by oral penicillin: report of case.
Topics: Administration, Oral; Adult; Anaphylaxis; Anesthesia, Dental; Anesthesia, General; Codeine; Diazepam | 1975 |
The administration of radiographic contrast media to patients with a history of a previous reaction.
Topics: Adult; Aged; Cholecystography; Contrast Media; Diphenhydramine; Drug Hypersensitivity; Humans; Middl | 1975 |
Fluid therapy in severe systemic reaction to radiopaque dye.
Topics: Anaphylaxis; Blood Pressure; Cardiac Catheterization; Contrast Media; Diphenhydramine; Drug Hypersen | 1975 |
Letter: Local anesthetics.
Topics: Anesthetics, Local; Diphenhydramine; Drug Hypersensitivity; Procaine; Tripelennamine | 1975 |
[Wissler's subsepsis allergica as a manifestation of drug allergy].
Topics: Adult; Aspirin; Diagnosis, Differential; Diphenhydramine; Dipyrone; Drug Hypersensitivity; Emergenci | 1992 |
Effects of flutropium on experimental models of drug- and allergy-induced rhinitis in guinea pigs.
Topics: Animals; Atropine; Atropine Derivatives; Cimetidine; Diphenhydramine; Drug Hypersensitivity; Guinea | 1991 |
Hypersensitivity reactions to epipodophyllotoxins in children with acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Bronchial Spasm | 1991 |
Systematic approach to diagnosis and management of biphasic insulin allergy with local anti-inflammatory agents.
Topics: Aged; Diabetes Mellitus; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Hydrocortisone; Hyp | 1989 |
Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Admin | 1987 |
Urticaria--a challenge in diagnosis and treatment.
Topics: Cold Temperature; Dermatitis, Contact; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Food Hyp | 1988 |
Allergic reactions to teniposide in patients with neuroblastoma and lymphoid malignancies.
Topics: Child; Child, Preschool; Diphenhydramine; Drug Hypersensitivity; Humans; Leukemia, Lymphoid; Lymphom | 1985 |
Successful treatment of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in hypersensitive AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Diphenhydramine; Drug Combinations; Drug Hypersensitivity | 1985 |
Primary contact sensitization site. A determinant for the localization of a diphenhydramine eruption.
Topics: Administration, Oral; Adult; Dermatitis, Toxicodendron; Diphenhydramine; Drug Eruptions; Drug Hypers | 1972 |
An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.
Topics: Adult; Black or African American; Dermatitis, Atopic; Diphenhydramine; Drug Eruptions; Drug Hypersen | 1965 |
[Effect of griseofulvin on the maintainance of thiamine and nicotinic acid reserves in psoriasis patients].
Topics: Adolescent; Adult; Aged; Balneology; Diphenhydramine; Drug Evaluation; Drug Hypersensitivity; Drug S | 1974 |
Treatment of anaphylaxis.
Topics: Anaphylaxis; Desensitization, Immunologic; Diphenhydramine; Drug Hypersensitivity; Ephedrine; Epinep | 1973 |
Benadryl and the IVP reaction.
Topics: Contrast Media; Diphenhydramine; Drug Hypersensitivity; Humans; Injections, Intravenous; Urography | 1972 |
Iodide mumps following excretory urography.
Topics: Atropine; Cortisone; Diatrizoate; Diphenhydramine; Drug Hypersensitivity; Humans; Inflammation; Male | 1972 |
Urticaria and anaphylactoid reactions after topical application of mechlorethamine.
Topics: Aged; Anaphylaxis; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Female; Humans; Mechloretham | 1973 |
Acute parotid gland swelling following intravenous injections of iodinated contrast medium.
Topics: Administration, Oral; Adult; Diatrizoate; Diphenhydramine; Drug Hypersensitivity; Female; Humans; In | 1973 |
Changes in renal size as related to blood pressure during an idiosyncratic reaction to radiographic contrast.
Topics: Blood Pressure; Diatrizoate; Diphenhydramine; Drug Hypersensitivity; Edema; Female; Humans; Hydrocor | 1974 |
A case of episodic urticaria due to saccharin ingestion.
Topics: Allergens; Bronchial Spasm; Diphenhydramine; Drug Hypersensitivity; Female; Hirsutism; Humans; Obesi | 1974 |
[2 cases of allergic reaction to dimedrol].
Topics: Adult; Diphenhydramine; Drug Hypersensitivity; Female; Humans | 1970 |
Diphenhydramine for local anesthesia in "caine" sensitive patients. A case report.
Topics: Adult; Anesthesia, Local; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Lidocaine; Warts | 1966 |
Anaphylaxis from alphazurine 2G during lymphography.
Topics: Adult; Coloring Agents; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Hodgkin Disease; Humans | 1966 |