diphenhydramine has been researched along with Disease Models, Animal in 32 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Excerpt | Relevance | Reference |
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"To evaluate the effects of diphenhydramine chloride (DPH) on mortality in a rat model of acute, severe organophosphate poisoning (OP)." | 7.71 | Diphenhydramine as a protective agent in a rat model of acute, lethal organophosphate poisoning. ( Bird, SB; Dickson, EW; Gaspari, RJ; Lee, WJ, 2002) |
"Acetylshikonin, a naphthoquinone isolated from the Chinese herb medicine, tzu ts'ao, was demonstrated to inhibit the polymyxin B-induced hind-paw edema in normal as well as in adrenalectomized mice." | 7.69 | Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin. ( Chang, LC; Kuo, SC; Raung, SL; Wang, JP, 1995) |
"Baseline weight, hemodynamic parameters, QRS interval, time to hypotension, and diphenhydramine dose required to achieve hypotension were similar between groups." | 5.22 | Intravenous Lipid Emulsion Therapy for Severe Diphenhydramine Toxicity: A Randomized, Controlled Pilot Study in a Swine Model. ( Bebarta, VS; Boudreau, SM; Castaneda, M; Vargas, TE; Varney, SM; Zarzabal, LA, 2016) |
" Then, we combined it with different doses of psychostimulants (d-amphetamine, modafinil, caffeine) to find the best combination for motion sickness." | 3.83 | The Combination of Scopolamine and Psychostimulants for the Prevention of Severe Motion Sickness. ( Han, B; Liu, AJ; Liu, HQ; Song, XR; Tian, JS; Yu, XH; Zhang, LL; Zhang, Y, 2016) |
"3% w/v (weight of solute per volume of solution) monoethanolamine (MEA) into his lungs, causing asthma-like symptoms." | 3.75 | Effects of inhaled monoethanolamine on bronchoconstriction. ( Hayashi, I; Ide, A; Kamijo, Y; Majima, M; Soma, K; Yoshimura, K, 2009) |
" This research first proposed that alterations of mast cell histamine release, gastric acid back-diffusion and mucosal microvascular permeability are important in modulating gastric ulcer and hemorrhage in Salmonella typhi-infected rats." | 3.72 | Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats. ( Hung, CR; Wang, PS, 2004) |
"To evaluate the effects of diphenhydramine chloride (DPH) on mortality in a rat model of acute, severe organophosphate poisoning (OP)." | 3.71 | Diphenhydramine as a protective agent in a rat model of acute, lethal organophosphate poisoning. ( Bird, SB; Dickson, EW; Gaspari, RJ; Lee, WJ, 2002) |
"Acetylshikonin, a naphthoquinone isolated from the Chinese herb medicine, tzu ts'ao, was demonstrated to inhibit the polymyxin B-induced hind-paw edema in normal as well as in adrenalectomized mice." | 3.69 | Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin. ( Chang, LC; Kuo, SC; Raung, SL; Wang, JP, 1995) |
"Although diphenhydramine hydrochloride is known to eliminate or reduce the symptoms of dystonia in human patients with acute dystonic reactions and idiopathic torsion dystonia, its mechanism of action is still unclear." | 3.69 | Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine. ( Matsumoto, RR; Stone, MR; Truong, DD; van't Groenewout, JL; Vo, VN, 1995) |
"In conclusion, pulmonary inflammation and peripheral thrombosis are correlated at 6 and 24 hours, but at 1 hour, the prothrombotic effects do not appear to result from pulmonary inflammation but possibly from the blood penetration of DEP-associated components or by DEP particles themselves." | 1.32 | Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine. ( Hoet, PH; Hoylaerts, MF; Nemery, B; Nemmar, A; Vermylen, J, 2003) |
" Chronic administration of imipramine-HCl (1 and 5 mg/kg, i." | 1.27 | Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. ( Kameyama, T; Nagasaka, M; Yamada, K, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (15.63) | 18.7374 |
1990's | 8 (25.00) | 18.2507 |
2000's | 8 (25.00) | 29.6817 |
2010's | 9 (28.13) | 24.3611 |
2020's | 2 (6.25) | 2.80 |
Authors | Studies |
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Walsh, DA | 1 |
Green, JB | 1 |
Franzyshen, SK | 1 |
Nolan, JC | 1 |
Yanni, JM | 1 |
Solinski, HJ | 1 |
Dranchak, P | 1 |
Oliphant, E | 1 |
Gu, X | 1 |
Earnest, TW | 1 |
Braisted, J | 1 |
Inglese, J | 1 |
Hoon, MA | 1 |
Abrams, RPM | 1 |
Yasgar, A | 1 |
Teramoto, T | 1 |
Lee, MH | 1 |
Dorjsuren, D | 1 |
Eastman, RT | 1 |
Malik, N | 1 |
Zakharov, AV | 1 |
Li, W | 1 |
Bachani, M | 1 |
Brimacombe, K | 1 |
Steiner, JP | 1 |
Hall, MD | 1 |
Balasubramanian, A | 1 |
Jadhav, A | 1 |
Padmanabhan, R | 1 |
Simeonov, A | 1 |
Nath, A | 1 |
Qutob, HMH | 1 |
Saad, RA | 1 |
Bali, H | 1 |
Osailan, A | 1 |
Jaber, J | 1 |
Alzahrani, E | 1 |
Alyami, J | 1 |
Elsayed, H | 1 |
Alserihi, R | 1 |
Shaikhomar, OA | 1 |
Divya, KM | 1 |
Savitha, DP | 1 |
Krishna, GA | 1 |
Dhanya, TM | 1 |
Mohanan, PV | 1 |
Shah, SF | 1 |
Jafry, AT | 1 |
Hussain, G | 1 |
Kazim, AH | 1 |
Ali, M | 1 |
Rivani, E | 1 |
Endraswari, PD | 1 |
Widodo, ADW | 1 |
Khalil, MR | 1 |
Guldberg, R | 1 |
Nørgård, BM | 1 |
Uldbjerg, N | 1 |
Wehberg, S | 1 |
Fowobaje, KR | 1 |
Mashood, LO | 1 |
Ekholuenetale, M | 1 |
Ibidoja, OJ | 1 |
Romagnoli, A | 1 |
D'Agostino, M | 1 |
Pavoni, E | 1 |
Ardiccioni, C | 1 |
Motta, S | 1 |
Crippa, P | 1 |
Biagetti, G | 1 |
Notarstefano, V | 1 |
Rexha, J | 1 |
Perta, N | 1 |
Barocci, S | 1 |
Costabile, BK | 1 |
Colasurdo, G | 1 |
Caucci, S | 1 |
Mencarelli, D | 1 |
Turchetti, C | 1 |
Farina, M | 1 |
Pierantoni, L | 1 |
La Teana, A | 1 |
Al Hadi, R | 1 |
Cicconardi, F | 1 |
Chinappi, M | 1 |
Trucchi, E | 1 |
Mancia, F | 1 |
Menzo, S | 1 |
Morozzo Della Rocca, B | 1 |
D'Annessa, I | 1 |
Di Marino, D | 1 |
Choya, A | 1 |
de Rivas, B | 1 |
Gutiérrez-Ortiz, JI | 1 |
López-Fonseca, R | 1 |
Xu, S | 1 |
Cheng, B | 1 |
Huang, Z | 1 |
Liu, T | 1 |
Li, Y | 1 |
Jiang, L | 1 |
Guo, W | 1 |
Xiong, J | 1 |
Amirazodi, M | 1 |
Daryanoosh, F | 1 |
Mehrabi, A | 1 |
Gaeini, A | 1 |
Koushkie Jahromi, M | 1 |
Salesi, M | 1 |
Zarifkar, AH | 1 |
Studeny, P | 1 |
Netukova, M | 1 |
Nemcokova, M | 1 |
Klimesova, YM | 1 |
Krizova, D | 1 |
Kang, H | 1 |
Tao, Y | 1 |
Zhang, Q | 1 |
Sha, D | 1 |
Chen, Y | 1 |
Yao, J | 1 |
Gao, Y | 1 |
Liu, J | 1 |
Ji, L | 1 |
Shi, P | 1 |
Shi, C | 1 |
Wu, YL | 1 |
Wright, AI | 1 |
M El-Metwaly, N | 1 |
A Katouah, H | 1 |
El-Desouky, MG | 1 |
El-Bindary, AA | 1 |
El-Bindary, MA | 1 |
Kostakis, ID | 1 |
Raptis, DA | 1 |
Davidson, BR | 1 |
Iype, S | 1 |
Nasralla, D | 1 |
Imber, C | 1 |
Sharma, D | 1 |
Pissanou, T | 1 |
Pollok, JM | 1 |
Hughes, AM | 1 |
Sanderson, E | 1 |
Morris, T | 1 |
Ayorech, Z | 1 |
Tesli, M | 1 |
Ask, H | 1 |
Reichborn-Kjennerud, T | 1 |
Andreassen, OA | 1 |
Magnus, P | 1 |
Helgeland, Ø | 1 |
Johansson, S | 1 |
Njølstad, P | 1 |
Davey Smith, G | 1 |
Havdahl, A | 1 |
Howe, LD | 1 |
Davies, NM | 1 |
Amrillah, T | 1 |
Prasetio, A | 1 |
Supandi, AR | 1 |
Sidiq, DH | 1 |
Putra, FS | 1 |
Nugroho, MA | 1 |
Salsabilla, Z | 1 |
Azmi, R | 1 |
Grammatikopoulos, P | 1 |
Bouloumis, T | 1 |
Steinhauer, S | 1 |
Mironov, VS | 2 |
Bazhenova, TA | 2 |
Manakin, YV | 2 |
Yagubskii, EB | 2 |
Yakushev, IA | 1 |
Gilmutdinov, IF | 1 |
Simonov, SV | 1 |
Lan, K | 1 |
Yang, H | 1 |
Zheng, J | 1 |
Hu, H | 1 |
Zhu, T | 1 |
Zou, X | 1 |
Hu, B | 1 |
Liu, H | 1 |
Olokede, O | 1 |
Wu, H | 1 |
Holtzapple, M | 1 |
Gungor, O | 1 |
Kose, M | 1 |
Ghaemi, R | 1 |
Acker, M | 1 |
Stosic, A | 1 |
Jacobs, R | 1 |
Selvaganapathy, PR | 1 |
Ludwig, N | 1 |
Yerneni, SS | 1 |
Azambuja, JH | 1 |
Pietrowska, M | 1 |
Widłak, P | 1 |
Hinck, CS | 1 |
Głuszko, A | 1 |
Szczepański, MJ | 1 |
Kärmer, T | 1 |
Kallinger, I | 1 |
Schulz, D | 1 |
Bauer, RJ | 1 |
Spanier, G | 1 |
Spoerl, S | 1 |
Meier, JK | 1 |
Ettl, T | 1 |
Razzo, BM | 1 |
Reichert, TE | 1 |
Hinck, AP | 1 |
Whiteside, TL | 1 |
Wei, ZL | 1 |
Juan, W | 1 |
Tong, D | 1 |
Juan, LX | 1 |
Sa, LY | 1 |
Jie, HFM | 1 |
Xiao, G | 1 |
Xiang, LG | 1 |
Jie, HM | 1 |
Xu, C | 1 |
Yu, DN | 1 |
Yao, ZX | 1 |
Bigdeli, F | 1 |
Gao, XM | 1 |
Cheng, X | 1 |
Li, JZ | 1 |
Zhang, JW | 1 |
Wang, W | 2 |
Guan, ZJ | 1 |
Bu, Y | 1 |
Liu, KG | 1 |
Morsali, A | 1 |
Das, R | 1 |
Paul, R | 1 |
Parui, A | 1 |
Shrotri, A | 1 |
Atzori, C | 1 |
Lomachenko, KA | 1 |
Singh, AK | 1 |
Mondal, J | 1 |
Peter, SC | 1 |
Florimbio, AR | 1 |
Coughlin, LN | 1 |
Bauermeister, JA | 1 |
Young, SD | 1 |
Zimmerman, MA | 1 |
Walton, MA | 1 |
Bonar, EE | 1 |
Demir, D | 1 |
Balci, AB | 1 |
Kahraman, N | 1 |
Sunbul, SA | 1 |
Gucu, A | 1 |
Seker, IB | 1 |
Badem, S | 1 |
Yuksel, A | 1 |
Ozyazicioglu, AF | 1 |
Goncu, MT | 1 |
Zhang, H | 1 |
Zhou, H | 1 |
Deng, Z | 1 |
Luo, L | 1 |
Ong, SP | 1 |
Wang, C | 1 |
Xin, H | 1 |
Whittingham, MS | 1 |
Zhou, G | 1 |
Maemura, R | 1 |
Wakamatsu, M | 1 |
Matsumoto, K | 1 |
Sakaguchi, H | 1 |
Yoshida, N | 1 |
Hama, A | 1 |
Yoshida, T | 1 |
Miwata, S | 1 |
Kitazawa, H | 1 |
Narita, K | 1 |
Kataoka, S | 1 |
Ichikawa, D | 1 |
Hamada, M | 1 |
Taniguchi, R | 1 |
Suzuki, K | 1 |
Kawashima, N | 1 |
Nishikawa, E | 1 |
Narita, A | 1 |
Okuno, Y | 1 |
Nishio, N | 1 |
Kato, K | 1 |
Kojima, S | 1 |
Morita, K | 1 |
Muramatsu, H | 1 |
Takahashi, Y | 1 |
Yirgu, A | 1 |
Mekonnen, Y | 1 |
Eyado, A | 1 |
Staropoli, A | 1 |
Vinale, F | 1 |
Zac, J | 1 |
Zac, S | 1 |
Pérez-Padilla, R | 1 |
Remigio-Luna, A | 1 |
Guzmán-Boulloud, N | 1 |
Gochicoa-Rangel, L | 1 |
Guzmán-Valderrábano, C | 1 |
Thirión-Romero, I | 1 |
Statsenko, ME | 1 |
Turkina, SV | 1 |
Barantsevich, ER | 1 |
Karakulova, YV | 1 |
Baranova, NS | 1 |
Morzhukhina, MV | 1 |
Wang, Q | 1 |
Gu, Y | 1 |
Chen, C | 1 |
Qiao, L | 1 |
Pan, F | 1 |
Song, C | 1 |
Canetto, SS | 1 |
Entilli, L | 1 |
Cerbo, I | 1 |
Cipolletta, S | 1 |
Wu, Y | 2 |
Zhu, P | 1 |
Jiang, Y | 1 |
Zhang, X | 1 |
Wang, Z | 2 |
Xie, B | 1 |
Song, T | 1 |
Zhang, F | 1 |
Luo, A | 1 |
Li, S | 1 |
Xiong, X | 1 |
Han, J | 1 |
Peng, X | 1 |
Li, M | 1 |
Huang, L | 1 |
Chen, Q | 1 |
Fang, W | 1 |
Hou, Y | 1 |
Zhu, Y | 1 |
Ye, J | 1 |
Liu, L | 1 |
Islam, MR | 1 |
Sanderson, P | 1 |
Johansen, MP | 1 |
Payne, TE | 1 |
Naidu, R | 1 |
Cao, J | 1 |
Yang, J | 1 |
Niu, X | 1 |
Liu, X | 1 |
Zhai, Y | 1 |
Qiang, C | 1 |
Niu, Y | 1 |
Li, Z | 1 |
Dong, N | 1 |
Wen, B | 1 |
Ouyang, Z | 1 |
Zhang, Y | 2 |
Li, J | 2 |
Zhao, M | 2 |
Zhao, J | 1 |
Morici, P | 1 |
Rizzato, C | 1 |
Ghelardi, E | 1 |
Rossolini, GM | 1 |
Lupetti, A | 1 |
Gözüküçük, R | 1 |
Cakiroglu, B | 1 |
He, X | 1 |
Li, R | 1 |
Zhao, D | 1 |
Zhang, L | 1 |
Ji, X | 1 |
Fan, X | 1 |
Chen, J | 1 |
Wang, Y | 1 |
Luo, Y | 1 |
Zheng, D | 1 |
Xie, L | 1 |
Sun, S | 1 |
Cai, Z | 1 |
Liu, Q | 1 |
Ma, K | 1 |
Sun, X | 1 |
Drinkwater, JJ | 1 |
Davis, TME | 1 |
Turner, AW | 1 |
Davis, WA | 1 |
Suzuki, Y | 1 |
Mizuta, Y | 1 |
Mikagi, A | 1 |
Misawa-Suzuki, T | 1 |
Tsuchido, Y | 1 |
Sugaya, T | 1 |
Hashimoto, T | 1 |
Ema, K | 1 |
Hayashita, T | 1 |
Chen, YW | 1 |
Tzeng, JI | 1 |
Chen, TY | 1 |
Wang, JJ | 1 |
Chen, YC | 1 |
Hung, CH | 1 |
Varney, SM | 1 |
Bebarta, VS | 1 |
Boudreau, SM | 1 |
Vargas, TE | 1 |
Castaneda, M | 1 |
Zarzabal, LA | 1 |
Yamamoto, K | 1 |
Kato, N | 1 |
Isogai, Y | 1 |
Kuroda, T | 1 |
Ishida, T | 2 |
Yamatodani, A | 1 |
Zhang, LL | 1 |
Liu, HQ | 1 |
Yu, XH | 1 |
Tian, JS | 1 |
Song, XR | 1 |
Han, B | 1 |
Liu, AJ | 1 |
Sun, D | 1 |
Guan, Y | 1 |
Sang, D | 1 |
Liu, M | 1 |
Pu, Y | 1 |
Fang, X | 1 |
Wang, D | 1 |
Huang, A | 1 |
Bi, X | 1 |
Cao, L | 1 |
He, C | 1 |
Gosselin, S | 1 |
Hoegberg, LC | 1 |
Hoffman, RS | 1 |
Graudins, A | 1 |
Stork, CM | 1 |
Thomas, SH | 1 |
Stellpflug, SJ | 1 |
Hayes, BD | 1 |
Levine, M | 1 |
Morris, M | 1 |
Nesbitt-Miller, A | 1 |
Turgeon, AF | 1 |
Bailey, B | 1 |
Calello, DP | 1 |
Chuang, R | 1 |
Bania, TC | 1 |
Mégarbane, B | 1 |
Bhalla, A | 1 |
Lavergne, V | 1 |
Kamijo, Y | 1 |
Hayashi, I | 1 |
Ide, A | 1 |
Yoshimura, K | 1 |
Soma, K | 1 |
Majima, M | 1 |
Tokunaga, S | 1 |
Tsutsui, R | 1 |
Obara, Y | 1 |
Kamei, C | 1 |
Chen, D | 1 |
Xiong, Y | 1 |
Wang, L | 1 |
Lv, B | 1 |
Lin, Y | 1 |
Lin, TK | 1 |
Man, MQ | 1 |
Santiago, JL | 1 |
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Roelandt, T | 1 |
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Gschwandtner, M | 1 |
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Trullas, C | 1 |
Tschachler, E | 1 |
Feingold, KR | 1 |
Elias, PM | 1 |
Bird, SB | 2 |
Gaspari, RJ | 2 |
Lee, WJ | 1 |
Dickson, EW | 2 |
Nemmar, A | 1 |
Nemery, B | 1 |
Hoet, PH | 1 |
Vermylen, J | 1 |
Hoylaerts, MF | 1 |
Hung, CR | 1 |
Wang, PS | 1 |
Chan, SW | 1 |
Rudd, JA | 1 |
Lin, G | 1 |
Li, P | 1 |
Rasti, M | 1 |
Parvaresh, E | 1 |
Tavajoh, S | 1 |
Talaei, M | 1 |
Wang, JP | 1 |
Raung, SL | 1 |
Chang, LC | 1 |
Kuo, SC | 1 |
van't Groenewout, JL | 1 |
Stone, MR | 1 |
Vo, VN | 1 |
Truong, DD | 1 |
Matsumoto, RR | 1 |
Moriuchi, H | 1 |
Arai, I | 1 |
Yuizono, T | 1 |
Weber, JR | 1 |
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Rosenkranz, T | 1 |
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Einhäupl, KM | 1 |
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Sofia, RD | 1 |
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Kubota, T | 1 |
Imokawa, H | 1 |
Inoue, H | 1 |
Ishida, H | 1 |
Ogino, Y | 1 |
Kameyama, T | 1 |
Nagasaka, M | 1 |
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Kontos, HA | 1 |
Richardson, DW | 1 |
Raper, AJ | 1 |
Patterson, JL | 1 |
Radostina, AI | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Skin Barrier Dysfunction and the Role of Skin Barrier Restoration on Cutaneous and Systemic Inflammation in the Aged Population[NCT03728569] | Early Phase 1 | 14 participants (Actual) | Interventional | 2018-05-16 | Terminated (stopped due to Enrollment and interactions/interventions paused due to COVID-19. Not expected to resume in the future. This is not a suspension of IRB approval) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for diphenhydramine and Disease Models, Animal
Article | Year |
---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning
Topics: Administration, Intravenous; Anesthetics; Animals; Calcium Channel Blockers; Cocaine; Diphenhydramin | 2016 |
2 trials available for diphenhydramine and Disease Models, Animal
Article | Year |
---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Intravenous Lipid Emulsion Therapy for Severe Diphenhydramine Toxicity: A Randomized, Controlled Pilot Study in a Swine Model.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Fat Emulsions, Intravenous; Female; Hemodynamics; | 2016 |
29 other studies available for diphenhydramine and Disease Models, Animal
Article | Year |
---|---|
Synthesis and antiallergy activity of N-[2-(dimethylamino)ethyl]-4-aryl-1-piperazinecarboxamide derivatives.
Topics: Anaphylaxis; Animals; Dimethylamines; Disease Models, Animal; Guinea Pigs; Histamine H1 Antagonists; | 1990 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Diphenhydramine produces local cutaneous analgesia in response to dorsal skin noxious stimuli in the rat.
Topics: Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Diphen | 2014 |
Induction and antagonism of pica induced by teriparatide in rats.
Topics: Age Factors; Animals; Anorexia; Antiemetics; Diphenhydramine; Disease Models, Animal; Dopamine D2 Re | 2015 |
The Combination of Scopolamine and Psychostimulants for the Prevention of Severe Motion Sickness.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Ch | 2016 |
Disulfiram and Diphenhydramine Hydrochloride Upregulate miR-30a to Suppress IL-17-Associated Autoimmune Inflammation.
Topics: Animals; Case-Control Studies; Cell Differentiation; Cells, Cultured; Diphenhydramine; Disease Model | 2016 |
Effects of inhaled monoethanolamine on bronchoconstriction.
Topics: Aerosols; Air Pollutants, Occupational; Airway Obstruction; Airway Resistance; Animals; Asthma; Atro | 2009 |
Effects of histamine H1-antagonists on sleep-awake state in rats placed on a grid suspended over water or on sawdust.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Chlorpheniramine; Diphenhydramine; Disease | 2009 |
Characteristics of emodin on modulating the contractility of jejunal smooth muscle.
Topics: Animals; Atropine; Constipation; Diarrhea; Diphenhydramine; Disease Models, Animal; Dose-Response Re | 2012 |
Topical antihistamines display potent anti-inflammatory activity linked in part to enhanced permeability barrier function.
Topics: Administration, Topical; Animals; Cell Differentiation; Cimetidine; Dermatitis, Atopic; Dermatitis, | 2013 |
Diphenhydramine as a protective agent in a rat model of acute, lethal organophosphate poisoning.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Histamine H1 Antagonists; Male; Organophosphate Po | 2002 |
Early death due to severe organophosphate poisoning is a centrally mediated process.
Topics: Animals; Central Nervous System Diseases; Cholinergic Antagonists; Dichlorvos; Diphenhydramine; Dise | 2003 |
Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Diphenhydramine; Disease Models, Animal; Histamin | 2003 |
Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Capillary Permeability; Diphenhydramine; Disease Models, | 2004 |
Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).
Topics: Analysis of Variance; Animals; Antiemetics; Antitussive Agents; Baclofen; Cevanes; Codeine; Copper S | 2007 |
The comparison of diphenhydramine HCl and Nedocromil sodium in prevention of abdominal postoperative adhesion formation in rat models: an experimental study.
Topics: Abdominal Cavity; Animals; Anti-Inflammatory Agents; Diphenhydramine; Disease Models, Animal; Female | 2007 |
Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin.
Topics: Adrenalectomy; Animals; Anthraquinones; Bradykinin; Capillary Permeability; Cell Degranulation; Dexa | 1995 |
Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Halope | 1995 |
Tranexamic acid attenuates oleic-acid-induced pulmonary extravasation.
Topics: Analysis of Variance; Animals; Capillary Permeability; Diphenhydramine; Disease Models, Animal; Dose | 1995 |
Histamine (H1) receptor antagonist inhibits leukocyte rolling in pial vessels in the early phase of bacterial meningitis in rats.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Histamine; Leukocytes; Male; Meningitis, Bacterial | 1997 |
Histamine receptor antagonists, cyclooxygenase blockade, and tumor necrosis factor during acute septic insult.
Topics: Animals; Bacteremia; Blood Pressure; Cardiac Output; Cimetidine; Cyclooxygenase Inhibitors; Diphenhy | 1998 |
In vitro studies of antigen-induced bronchospasm.
Topics: Airway Obstruction; Animals; Antigens; Bronchi; Bronchial Spasm; Chromones; Diphenhydramine; Disease | 1979 |
Failure of diphenhydramine hydrochloride to prevent thrombosis at sites of endarterectomy in dogs.
Topics: Animals; Carotid Arteries; Diphenhydramine; Disease Models, Animal; Dogs; Endarterectomy; Female; Fe | 1978 |
Repeated aeroallergen challenge induces lung dysfunction but not bronchial hyperresponsiveness in conscious guinea pigs.
Topics: Acetylcholine; Aerosols; Airway Resistance; Allergens; Animals; Bronchial Hyperreactivity; Diphenhyd | 1992 |
[Study on ear burn model in mice and its significant application].
Topics: Animals; Bradykinin; Burns; Capillary Permeability; Dexamethasone; Diphenhydramine; Disease Models, | 1990 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhy | 1985 |
Mechanisms of action of hypocapnic alkalosis on limb blood vessels in man and dog.
Topics: Alkalosis; Alkalosis, Respiratory; Animals; Blood Pressure; Carbon Dioxide; Diphenhydramine; Disease | 1972 |
[Effect of an antihistamic preparation (dimedrol) on the morphology and function of connective tissue cellular elements under conditions of aseptic inflammation].
Topics: Animals; Capillary Permeability; Cell Migration Inhibition; Cell Movement; Connective Tissue; Connec | 1970 |