diphenhydramine has been researched along with Dermatitis Medicamentosa in 35 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of allergic reaction associated with the administration of intravenous ketamine for procedural sedation in a 16-year-old male." | 7.85 | Allergic Reaction to Ketamine as Monotherapy for Procedural Sedation. ( Baker, B; Ferguson, JD; Nguyen, TT, 2017) |
| "Three cases of contact dermatitis caused by an ethanolamine antihistamine, diphenhydramine hydrochloride (Benadryl), are described." | 7.66 | Contact dermatitis caused by diphenhydramine hydrochloride. ( Coskey, RJ, 1983) |
| "A chart review of the breast cancer SLN database was performed; it included 2392 sequential patients who underwent SLN biopsy involving isosulfan blue dye at Memorial Sloan-Kettering Cancer Center from September 12, 1996, to August 17, 2000." | 5.31 | Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer. ( Borgen, PI; Cody, HS; Fey, J; Gemignani, M; Heerdt, AS; Montgomery, LL; Petrek, J; Port, E; Thorne, AC; Van Zee, KJ, 2002) |
| "We report a case of allergic reaction associated with the administration of intravenous ketamine for procedural sedation in a 16-year-old male." | 3.85 | Allergic Reaction to Ketamine as Monotherapy for Procedural Sedation. ( Baker, B; Ferguson, JD; Nguyen, TT, 2017) |
| "As experience with beta-blocker use in patients with congestive heart failure is increasing, enthusiasm for carvedilol use in these patients is also increasing." | 3.70 | Possible adverse skin reaction to carvedilol. ( Gutierrez, R; Lo, A; Simpson, SH; Teo, KK; Tsuyuki, RT, 1998) |
| "Three cases of contact dermatitis caused by an ethanolamine antihistamine, diphenhydramine hydrochloride (Benadryl), are described." | 3.66 | Contact dermatitis caused by diphenhydramine hydrochloride. ( Coskey, RJ, 1983) |
| "Temsirolimus (CCI-779) is a novel inhibitor of the mammalian target of rapamycin." | 2.75 | A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors. ( Fujisaka, Y; Horiike, A; Tamura, T; Yamada, Y; Yamamoto, N, 2010) |
| "A chart review of the breast cancer SLN database was performed; it included 2392 sequential patients who underwent SLN biopsy involving isosulfan blue dye at Memorial Sloan-Kettering Cancer Center from September 12, 1996, to August 17, 2000." | 1.31 | Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer. ( Borgen, PI; Cody, HS; Fey, J; Gemignani, M; Heerdt, AS; Montgomery, LL; Petrek, J; Port, E; Thorne, AC; Van Zee, KJ, 2002) |
| "Diphenhydramine was chosen as test substance because it is the most widely used topical antihistamine in Europe and is, moreover, prescribed for several indications." | 1.27 | [Allergy to topical antihistamines--discrepancy between the literature and clinical practice]. ( Aberer, W; Tappeiner, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (28.57) | 18.7374 |
| 1990's | 10 (28.57) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 7 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, DC | 1 |
| Feldman, DN | 1 |
| Kim, LK | 1 |
| Minutello, RM | 1 |
| Bergman, G | 1 |
| Wong, SC | 1 |
| Swaminathan, RV | 1 |
| Yokose, C | 1 |
| Nakai, N | 1 |
| Katoh, N | 1 |
| Kolbe, AB | 1 |
| Hartman, RP | 1 |
| Hoskin, TL | 1 |
| Carter, RE | 1 |
| Maddox, DE | 1 |
| Hunt, CH | 1 |
| Hesley, GK | 1 |
| Cuervo-Pardo, L | 1 |
| Gonzalez-Estrada, A | 1 |
| Fernandez, J | 1 |
| Pien, LC | 1 |
| Nguyen, TT | 1 |
| Baker, B | 1 |
| Ferguson, JD | 1 |
| Fernández-Jorge, B | 1 |
| Goday Buján, J | 1 |
| Fernández-Torres, R | 1 |
| Rodríguez-Lojo, R | 1 |
| Fonseca, E | 1 |
| Smith, TL | 1 |
| Baldwin, A | 1 |
| Cunningham, LL | 1 |
| Cook, AM | 1 |
| WILLCOX, RR | 1 |
| Fujisaka, Y | 1 |
| Yamada, Y | 1 |
| Yamamoto, N | 1 |
| Horiike, A | 1 |
| Tamura, T | 1 |
| Coulter, DW | 1 |
| Walko, C | 1 |
| Patel, J | 1 |
| Moats-Staats, BM | 1 |
| McFadden, A | 1 |
| Smith, SV | 1 |
| Khan, WA | 1 |
| Bridges, AS | 1 |
| Deal, AM | 1 |
| Oesterheld, J | 1 |
| Davis, IJ | 1 |
| Blatt, J | 1 |
| Montgomery, LL | 1 |
| Thorne, AC | 1 |
| Van Zee, KJ | 1 |
| Fey, J | 1 |
| Heerdt, AS | 1 |
| Gemignani, M | 1 |
| Port, E | 1 |
| Petrek, J | 1 |
| Cody, HS | 1 |
| Borgen, PI | 1 |
| Ketkar, M | 1 |
| Shrier, D | 1 |
| Holdiness, MR | 1 |
| JIRASEK, L | 1 |
| SCHWANK, R | 1 |
| HARTMAN, DL | 1 |
| DICKEY, RF | 1 |
| MacGinnitie, AJ | 1 |
| Walensky, LD | 1 |
| Turvey, SE | 1 |
| Orange, JS | 1 |
| Bonilla, FA | 1 |
| Silverman, LB | 1 |
| Oettgen, H | 1 |
| Studdiford, J | 1 |
| Oppenheim, L | 1 |
| McCann, E | 1 |
| Altshuler, M | 1 |
| Coskey, RJ | 1 |
| Baker, BA | 1 |
| Cacchione, JG | 1 |
| Dwyer, CM | 1 |
| Dick, D | 1 |
| Andersen, JM | 1 |
| Goodfellow, LM | 1 |
| Marra, CA | 1 |
| Shalansky, KF | 1 |
| Hicks, ME | 1 |
| Smith, CL | 1 |
| Stein, GE | 1 |
| Simpson, SH | 1 |
| Tsuyuki, RT | 1 |
| Gutierrez, R | 1 |
| Lo, A | 1 |
| Teo, KK | 1 |
| Renz, CL | 1 |
| Thurn, JD | 1 |
| Finn, HA | 1 |
| Lynch, JP | 1 |
| Moss, J | 1 |
| Yusin, JS | 1 |
| Crawford, WW | 1 |
| Klaustermeyer, WB | 1 |
| Postovsky, S | 1 |
| Elhasid, R | 1 |
| Ben-Barak, A | 1 |
| Levin, K | 1 |
| Ben Arush, MW | 1 |
| Toma, E | 1 |
| Fournier, S | 1 |
| Aberer, W | 1 |
| Tappeiner, G | 1 |
| Fan-Havard, P | 1 |
| Nahata, MC | 1 |
| Barson, WJ | 1 |
| Bartkowski, H | 1 |
| Kosnik, E | 1 |
| Shelley, WB | 1 |
| Bennett, RG | 1 |
| Davenport, PM | 1 |
| Wilhelm, RE | 1 |
| Csonka, GW | 1 |
| Emmett, EA | 1 |
4 trials available for diphenhydramine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors.
Topics: Adult; Aged; Anti-Allergic Agents; Antineoplastic Agents; Area Under Curve; Carcinoma, Renal Cell; C | 2010 |
Valproic acid reduces the tolerability of temsirolimus in children and adolescents with solid tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Diphenhydramine | 2013 |
Antihistamine prophylaxis permits rapid vancomycin infusion.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty; Cimetidine; Diphenhydramine; Do | 1999 |
Adverse reactions to co-trimoxazole in HIV infection.
Topics: Diphenhydramine; Double-Blind Method; Drug Eruptions; HIV Infections; Humans; Pneumonia, Pneumocysti | 1991 |
31 other studies available for diphenhydramine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
A strategy of 'treating through' a prasugrel-induced rash.
Topics: Diphenhydramine; Drug Eruptions; Exanthema; Glucocorticoids; Histamine H1 Antagonists; Humans; Male; | 2013 |
Maculopapular-type drug eruption caused by Coughcode(®)-N combination tablets.
Topics: Acetaminophen; Administration, Oral; Adolescent; Antitussive Agents; Bromisovalum; Codeine; Diphenhy | 2013 |
Premedication of patients for prior urticarial reaction to iodinated contrast medium.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Contrast Media; Diphenhydramine; Drug Erupt | 2014 |
A rash during surgery: rounding up the usual suspects.
Topics: Aged; Anti-Allergic Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Chlorhexidine; D | 2015 |
Allergic Reaction to Ketamine as Monotherapy for Procedural Sedation.
Topics: Adolescent; Anesthetics, Dissociative; Conscious Sedation; Diphenhydramine; Drug Eruptions; Emergenc | 2017 |
Concomitant allergic contact dermatitis from diphenhydramine and metronidazole.
Topics: Anti-Infective Agents; Dermatitis, Allergic Contact; Diphenhydramine; Drug Eruptions; Drug Therapy, | 2008 |
Rash associated with pregabalin use.
Topics: Administration, Oral; Adult; Analgesics; Anti-Allergic Agents; Diphenhydramine; Drug Eruptions; Fema | 2008 |
Use of benadryl for penicillin urticaria; preliminary report.
Topics: Amino Acids; Diphenhydramine; Drug Combinations; Drug Eruptions; Ethers; Penicillins; Sorbitol; Urti | 1946 |
Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer.
Topics: Anaphylaxis; Anesthesia; Breast Neoplasms; Coloring Agents; Cross Reactions; Databases, Factual; Dip | 2002 |
An allergic reaction to intraarterial nonionic contrast material.
Topics: Adult; Airway Obstruction; Bronchial Hyperreactivity; Carotid Artery, Common; Cerebral Angiography; | 2003 |
Rare systemic dermatologic reaction after pneumococcal vaccine administration.
Topics: Aged; Anti-Allergic Agents; Anti-Inflammatory Agents; Diphenhydramine; Drug Eruptions; Humans; Hydro | 2003 |
[OCCUPATIONAL CONTACT HYPERSENSITIVITY TO ANTIHISTAMINICS (BROMADRYL)].
Topics: Anti-Allergic Agents; Dermatitis, Contact; Dermatitis, Occupational; Diphenhydramine; Drug Eruptions | 1963 |
PHOTODERMATITIS INDUCED BY DRUGS. II. PHOTODERMATITIS MEDICAMENTOSA.
Topics: Anti-Bacterial Agents; Benzoates; Chlorothiazide; Diphenhydramine; Drug Eruptions; Estrogens; Geriat | 1964 |
Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.
Topics: Adolescent; Anaphylaxis; Anti-Allergic Agents; Antimetabolites, Antineoplastic; Antipruritics; Diphe | 2003 |
Erythema multiforme after meningitis vaccine: patient safety concerns with repeat immunization.
Topics: Adult; Diphenhydramine; Drug Eruptions; Erythema Multiforme; Histamine H1 Antagonists; Humans; Immun | 2006 |
Contact dermatitis caused by diphenhydramine hydrochloride.
Topics: Child; Dermatitis, Contact; Diphenhydramine; Drug Eruptions; Humans; Male; Middle Aged | 1983 |
Dermatologic cross-sensitivity between diltiazem and amlodipine.
Topics: Amlodipine; Diltiazem; Diphenhydramine; Drug Eruptions; Humans; Hydroxyzine; Male; Methylprednisolon | 1994 |
Fixed drug eruption caused by diphenhydramine.
Topics: Adult; Diphenhydramine; Drug Eruptions; Female; Humans | 1993 |
Suspected vein irritation from i.v. pentamidine isethionate.
Topics: Adult; Anti-Allergic Agents; Antifungal Agents; Antipruritics; Diphenhydramine; Drug Eruptions; Fema | 1996 |
Action stat. Adverse reaction to benadryl.
Topics: Adult; Amoxicillin; Anti-Allergic Agents; Coma; Diphenhydramine; Drug Eruptions; Emergency Nursing; | 1996 |
Ampicillin-induced maculopapular versus urticarial rash.
Topics: Ampicillin; Anti-Allergic Agents; Diagnosis, Differential; Diphenhydramine; Drug Eruptions; Drug Hyp | 1996 |
Trimethoprim/sulfamethoxazole-induced hypersensitivity syndrome.
Topics: Diphenhydramine; Drug Eruptions; Humans; Male; Methylprednisolone; Middle Aged; Trimethoprim, Sulfam | 1997 |
Possible adverse skin reaction to carvedilol.
Topics: Adrenergic beta-Antagonists; Antipruritics; Carbazoles; Carvedilol; Diphenhydramine; Drug Eruptions; | 1998 |
Facial edema, oral ulcers, and a cutaneous eruption following a dental procedure utilizing diflunisal and mepivacaine.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Diflunisal; Diphenhydram | 1999 |
Allergic reaction to high-dose methotrexate.
Topics: Adolescent; Anti-Anxiety Agents; Antimetabolites, Antineoplastic; Antipruritics; Bone Neoplasms; Dip | 2000 |
[Allergy to topical antihistamines--discrepancy between the literature and clinical practice].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diphenhydramine; Drug Eruptions; Female; Histamine H1 An | 1988 |
Histamine-like reaction after a single intravenous dose of rifampin.
Topics: Cerebrospinal Fluid Shunts; Diphenhydramine; Drug Eruptions; Erythema; Humans; Infant; Infusions, In | 1988 |
Primary contact sensitization site. A determinant for the localization of a diphenhydramine eruption.
Topics: Administration, Oral; Adult; Dermatitis, Toxicodendron; Diphenhydramine; Drug Eruptions; Drug Hypers | 1972 |
An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.
Topics: Adult; Black or African American; Dermatitis, Atopic; Diphenhydramine; Drug Eruptions; Drug Hypersen | 1965 |
Balanitis due to fixed eruption after Mandrax.
Topics: Adult; Balanitis; Diphenhydramine; Drug Eruptions; Humans; Male; Methaqualone | 1973 |
Diphenhydramine photoallergy.
Topics: Aged; Australia; Diphenhydramine; Drug Eruptions; Edema; Erythema; Female; Humans; Insect Bites and | 1974 |