Page last updated: 2024-10-26

diphenhydramine and Dermatitis, Atopic

diphenhydramine has been researched along with Dermatitis, Atopic in 11 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Research Excerpts

ExcerptRelevanceReference
"Atopic dermatitis is the most common form of eczema, a condition that causes the skin to become itchy, dry and cracked."3.01Abrocitinib for the treatment of atopic dermatitis. ( Gooderham, M; Lé, AM; Torres, T, 2023)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Lé, AM1
Gooderham, M1
Torres, T1
Papoiu, AD1
Valdes-Rodriguez, R1
Nattkemper, LA1
Chan, YH1
Hahn, GS1
Yosipovitch, G1
Murota, H1
Bae, S1
Hamasaki, Y1
Maruyama, R1
Katayama, I1
Lin, TK1
Man, MQ1
Santiago, JL1
Park, K1
Roelandt, T1
Oda, Y1
Hupe, M1
Crumrine, D1
Lee, HJ1
Gschwandtner, M1
Thyssen, JP1
Trullas, C1
Tschachler, E1
Feingold, KR1
Elias, PM1
SCHAFFER, K1
Lawrence, CM1
Byrne, JP1
Zur, G1
Ihrke, PJ1
White, SD1
Kass, PH1
Jacobs, AH1
Glukhen'kiĭ, BT1
Grando, SA1
Draelos, ZK1
Hansen, RC1
Davenport, PM1
Wilhelm, RE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Skin Barrier Dysfunction and the Role of Skin Barrier Restoration on Cutaneous and Systemic Inflammation in the Aged Population[NCT03728569]Early Phase 114 participants (Actual)Interventional2018-05-16Terminated (stopped due to Enrollment and interactions/interventions paused due to COVID-19. Not expected to resume in the future. This is not a suspension of IRB approval)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for diphenhydramine and Dermatitis, Atopic

ArticleYear
Abrocitinib for the treatment of atopic dermatitis.
    Immunotherapy, 2023, Volume: 15, Issue:16

    Topics: Cytokines; Dermatitis, Atopic; Diphenhydramine; Double-Blind Method; Humans; Sulfonamides; Treatment

2023

Trials

1 trial available for diphenhydramine and Dermatitis, Atopic

ArticleYear
A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch.
    Acta dermato-venereologica, 2013, Sep-04, Volume: 93, Issue:5

    Topics: Administration, Cutaneous; Adult; Analysis of Variance; Antipruritics; Chemistry, Pharmaceutical; De

2013

Other Studies

9 other studies available for diphenhydramine and Dermatitis, Atopic

ArticleYear
Emedastine difumarate inhibits histamine-induced collagen synthesis in dermal fibroblasts.
    Journal of investigational allergology & clinical immunology, 2008, Volume: 18, Issue:4

    Topics: Benzimidazoles; Cells, Cultured; Collagen Type I; Dermatitis, Atopic; Diphenhydramine; Fibroblasts;

2008
Topical antihistamines display potent anti-inflammatory activity linked in part to enhanced permeability barrier function.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:2

    Topics: Administration, Topical; Animals; Cell Differentiation; Cimetidine; Dermatitis, Atopic; Dermatitis,

2013
[Experiences with systral ointment in allergic skin diseases].
    Deutsches medizinisches Journal, 1957, Mar-15, Volume: 8, Issue:3

    Topics: Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; Diphenhydramine; Ethylamines; Humans

1957
Eczematous eruption from oral diphenhydramine.
    Contact dermatitis, 1981, Volume: 7, Issue:5

    Topics: Administration, Oral; Dermatitis, Atopic; Diphenhydramine; Female; Humans; Middle Aged; Nickel; Resp

1981
Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).
    Veterinary therapeutics : research in applied veterinary medicine, 2002,Spring, Volume: 3, Issue:1

    Topics: Allergens; Animals; Chlorpheniramine; Clemastine; Dermatitis, Atopic; Diphenhydramine; Dog Diseases;

2002
Management of atopic dermatitis in childhood.
    Modern problems in paediatrics, 1975, Volume: 17

    Topics: Dermatitis, Atopic; Diphenhydramine; Drug Combinations; Fatty Alcohols; Humans; Propylene Glycols; S

1975
[Suppression of the activity of biologically active substances for the relief of itching in atopic dermatitis].
    Sovetskaia meditsina, 1985, Issue:9

    Topics: Aminocaproates; Aminocaproic Acid; Dermatitis, Atopic; Diphenhydramine; Drug Therapy, Combination; H

1985
Polymorphic light eruption in childhood.
    Clinical pediatrics, 1985, Volume: 24, Issue:12

    Topics: Child; Dermatitis, Atopic; Diagnosis, Differential; Diphenhydramine; Drug Therapy, Combination; Halc

1985
An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.
    Archives of dermatology, 1965, Volume: 92, Issue:5

    Topics: Adult; Black or African American; Dermatitis, Atopic; Diphenhydramine; Drug Eruptions; Drug Hypersen

1965