diphenhydramine has been researched along with Depressive Disorder in 12 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diphenhydramine was used as an active control because of the significant sedation associated with AMPT." | 2.68 | Effects of alpha-methyl-para-tyrosine (AMPT) in drug-free depressed patients. ( Charney, DS; Delgado, PL; Heninger, GR; Miller, HL; Salomon, RM, 1996) |
| " Her elimination half-life for desipramine was found to be greatly prolonged, at approximately 150 hours." | 1.27 | Idiosyncratic pharmacokinetics complicating treatment of major depression in an elderly woman. ( Dugas, JE; Glassman, JN; Loyd, DW; Tsuang, MT, 1985) |
| " Chronic administration of imipramine-HCl (1 and 5 mg/kg, i." | 1.27 | Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. ( Kameyama, T; Nagasaka, M; Yamada, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ROBITSCHER, JB | 1 |
| PULVER, SE | 1 |
| SIMKO, A | 1 |
| Englert, I | 1 |
| Miller, HL | 2 |
| Delgado, PL | 2 |
| Salomon, RM | 2 |
| Berman, R | 1 |
| Krystal, JH | 1 |
| Heninger, GR | 2 |
| Charney, DS | 2 |
| Guthrie, SK | 1 |
| Sung, JC | 1 |
| Goodson, J | 1 |
| Grunhaus, L | 1 |
| Tandon, R | 1 |
| Park-Matsumoto, YC | 1 |
| Tazawa, T | 1 |
| Saltz, BL | 1 |
| Vitiello, B | 1 |
| Hill, JL | 1 |
| Elia, J | 1 |
| Cunningham, E | 1 |
| McLeer, SV | 1 |
| Behar, D | 1 |
| Schreiber, W | 1 |
| Pauls, AM | 1 |
| Krieg, JC | 1 |
| Glassman, JN | 1 |
| Dugas, JE | 1 |
| Tsuang, MT | 1 |
| Loyd, DW | 1 |
| Kameyama, T | 1 |
| Nagasaka, M | 1 |
| Yamada, K | 1 |
4 trials available for diphenhydramine and Depressive Disorder
| Article | Year |
|---|---|
Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression.
Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Brain Chemistry; Depres | 1996 |
Effects of alpha-methyl-para-tyrosine (AMPT) in drug-free depressed patients.
Topics: Adult; Aged; alpha-Methyltyrosine; Depressive Disorder; Diphenhydramine; Enzyme Inhibitors; Female; | 1996 |
Triazolam and diphenhydramine effects on seizure duration in depressed patients receiving ECT.
Topics: Adult; Aged; Depressive Disorder; Diphenhydramine; Electroconvulsive Therapy; Electroencephalography | 1996 |
P.r.n. medications in child psychiatric patients: a pilot placebo-controlled study.
Topics: Administration, Oral; Adolescent; Age Factors; Aggression; Attention Deficit Disorder with Hyperacti | 1991 |
8 other studies available for diphenhydramine and Depressive Disorder
| Article | Year |
|---|---|
Orphenadrine in the treatment of depression; a preliminary study.
Topics: Depression; Depressive Disorder; Diphenhydramine; Orphenadrine | 1958 |
[Evaluation and management of depressive states appearing during reserpine therapy].
Topics: Depression; Depressive Disorder; Diphenhydramine; Disease Management; Humans; Reserpine | 1958 |
[Diphenhydramin-overdose: anticholinergic symptoms, EEG-findings in the course and drug treatment of a gerontopsychiatric patient].
Topics: Aged; Brain; Cholinergic Antagonists; Dementia; Depressive Disorder; Diphenhydramine; Drug Therapy, | 2004 |
Neuroleptic malignant syndrome associated with diphenhydramine and diprophyllin overdose in a depressed patient.
Topics: Adult; Bronchodilator Agents; Depressive Disorder; Diphenhydramine; Drug Overdose; Dyphylline; Hista | 1999 |
Tardive dyskinesia in the elderly patient.
Topics: Aged; Chlorpromazine; Chronic Disease; Clonazepam; Clozapine; Depressive Disorder; Desipramine; Diph | 1992 |
[Toxic psychosis as an acute manifestation of diphenhydramine poisoning].
Topics: Acute Disease; Depressive Disorder; Diphenhydramine; Female; Humans; Middle Aged; Psychoses, Substan | 1988 |
Idiosyncratic pharmacokinetics complicating treatment of major depression in an elderly woman.
Topics: Depressive Disorder; Desipramine; Diphenhydramine; Female; Half-Life; Hospitalization; Humans; Kinet | 1985 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhy | 1985 |