diphenhydramine has been researched along with Dementia in 3 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-nine elderly residents of long-term care facilities who had DSM-III diagnoses of dementia were studied in an 8-week randomized, double-blind comparison trial of haloperidol, oxazepam, and diphenhydramine to test the efficacy of these agents in the treatment of clinically significant behavioral disturbances in patients with dementia." | 5.06 | Pharmacologic treatment of noncognitive behavioral disturbances in elderly demented patients. ( Coccaro, EF; Duvvi, K; Giordani, B; Kramer, E; Nora, R; Patel, BM; Rice, CM; Thorne, A; Torres, J; Zemishlany, Z, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Englert, I | 1 |
| Herz, LR | 1 |
| Volicer, L | 1 |
| Ross, V | 1 |
| Rheaume, Y | 1 |
| Coccaro, EF | 1 |
| Kramer, E | 1 |
| Zemishlany, Z | 1 |
| Thorne, A | 1 |
| Rice, CM | 1 |
| Giordani, B | 1 |
| Duvvi, K | 1 |
| Patel, BM | 1 |
| Torres, J | 1 |
| Nora, R | 1 |
2 trials available for diphenhydramine and Dementia
| Article | Year |
|---|---|
Pharmacotherapy of agitation in dementia.
Topics: Dementia; Diphenhydramine; Double-Blind Method; Humans; Oxazepam; Psychomotor Agitation; Thiothixene | 1992 |
Pharmacologic treatment of noncognitive behavioral disturbances in elderly demented patients.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Diphenhydramine; D | 1990 |
1 other study available for diphenhydramine and Dementia
| Article | Year |
|---|---|
[Diphenhydramin-overdose: anticholinergic symptoms, EEG-findings in the course and drug treatment of a gerontopsychiatric patient].
Topics: Aged; Brain; Cholinergic Antagonists; Dementia; Depressive Disorder; Diphenhydramine; Drug Therapy, | 2004 |