diphenhydramine has been researched along with Cough in 39 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the safety and efficacy of Linkus, Aminophylline with Diphenhydramine group and Acefyllin Piperazine with Diphenhydramine cough syrup on children having cough and sleep difficulty associated with cough." | 9.22 | Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children. ( Naveed, S; Rehman, H; Usmanghani, K, 2016) |
| "Twenty two subjects with acute viral upper respiratory tract infection (common cold) underwent cough reflex sensitivity measurement employing capsaicin challenge on 3 separate days, 2 h after ingesting single doses of study drug (to coincide with peak blood concentrations), administered in randomized, double-blind manner: a multicomponent syrup containing diphenhydramine (25 mg), phenylephrine (10 mg), in a natural cocoa formulation; dextromethorphan (30 mg) syrup; and, placebo syrup." | 9.20 | Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection. ( Brew, J; Caparros-Wanderley, W; Dhar, S; Dicpinigaitis, PV; Gayle, Y; Johnson, A, 2015) |
| "To determine whether the commonly used over-the-counter medications dextromethorphan and diphenhydramine are superior to placebo for the treatment of nocturnal cough and sleep difficulty associated with upper respiratory infections and to determine whether parents have improved sleep quality when their children receive the medications when compared with placebo." | 9.11 | Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents. ( Berlin, CM; Carlson, LC; Crowell, KR; Dilworth, DA; McMillan, HS; Paul, IM; Shaffer, ML; Yoder, KE, 2004) |
| "This controlled crossover study in twenty healthy volunteer subjects utilized the citric acid aerosol-induced cough response as a means to demonstrate the effectiveness of 25 mg of diphenhydramine as an antitussive." | 9.07 | Antitussive effects of diphenhydramine on the citric acid aerosol-induced cough response in humans. ( Ciccone, PE; Masurat, T; Packman, EW; Wilson, J, 1991) |
| "Lotussin and linctus diphenhydramine were compared for efficacy and patient preference in fifty patients suffering from post-infective cough." | 9.04 | A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough. ( Matts, SG, 1977) |
| "A double-blind crossover study was conducted to evaluate the antitussive effectiveness of diphenhydramine (DPH) in chornic coughs related to bronchitis, at doses of 25 and 50 mg every 4 hr for four doses." | 9.04 | Antitussive activity of diphenhydramine in chronic cough. ( Lilienfield, LS; Princiotto, JV; Rose, JC, 1976) |
| "To determine the efficacy of diphenhydramine against cough due to respiratory infection or irritation in patients/subjects without comorbidities." | 8.84 | Efficacy of diphenhydramine against cough in humans: a review. ( Björnsdóttir, I; Einarsdóttir, RA; Einarson, TR; Gudmundsson, LS, 2007) |
| "Coughing in a child induced by upper respiratory tract infections (URTIs) can be a problem, both for the child and its parents." | 6.84 | Comparison of the Effect of Two Kinds of Iranian Honey and Diphenhydramine on Nocturnal Cough and the Sleep Quality in Coughing Children and Their Parents. ( Allami, A; Ayazi, P; Beyhaghi, T; Esmailzadehha, N; Mahyar, A; Yousef-Zanjani, M, 2017) |
| "Coughing is a prevalent symptom of upper respiratory infections (URIs) that cause disturbance in the sleep of children and their parents." | 6.75 | A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents. ( Mozaffari-Khosravi, H; Mozayan, MR; Shadkam, MN, 2010) |
| "Night-time honey doses given to children with cough from URTI significantly reduces symptoms and improves children and caregivers sleep compared to Diphenhydramine DPH." | 5.51 | Effect of Honey on Cough Symptoms in Children with Upper Respiratory Tract Infection: A Randomised Controlled Trial. ( Abuba, T; Anibasa, FO; Dankyau, M, 2022) |
| "To investigate the efficacy and safety of CS1002, an over-the-counter cough treatment containing diphenhydramine, ammonium chloride and levomenthol in a cocoa-based demulcent." | 5.24 | Rococo study: a real-world evaluation of an over-the-counter medicine in acute cough (a multicentre, randomised, controlled study). ( Birring, SS; Brew, J; Edwards, V; Kilbourn, A; Morice, AH; Wilson, R, 2017) |
| "To evaluate the safety and efficacy of Linkus, Aminophylline with Diphenhydramine group and Acefyllin Piperazine with Diphenhydramine cough syrup on children having cough and sleep difficulty associated with cough." | 5.22 | Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children. ( Naveed, S; Rehman, H; Usmanghani, K, 2016) |
| "Twenty two subjects with acute viral upper respiratory tract infection (common cold) underwent cough reflex sensitivity measurement employing capsaicin challenge on 3 separate days, 2 h after ingesting single doses of study drug (to coincide with peak blood concentrations), administered in randomized, double-blind manner: a multicomponent syrup containing diphenhydramine (25 mg), phenylephrine (10 mg), in a natural cocoa formulation; dextromethorphan (30 mg) syrup; and, placebo syrup." | 5.20 | Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection. ( Brew, J; Caparros-Wanderley, W; Dhar, S; Dicpinigaitis, PV; Gayle, Y; Johnson, A, 2015) |
| "To determine whether the commonly used over-the-counter medications dextromethorphan and diphenhydramine are superior to placebo for the treatment of nocturnal cough and sleep difficulty associated with upper respiratory infections and to determine whether parents have improved sleep quality when their children receive the medications when compared with placebo." | 5.11 | Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents. ( Berlin, CM; Carlson, LC; Crowell, KR; Dilworth, DA; McMillan, HS; Paul, IM; Shaffer, ML; Yoder, KE, 2004) |
| "This controlled crossover study in twenty healthy volunteer subjects utilized the citric acid aerosol-induced cough response as a means to demonstrate the effectiveness of 25 mg of diphenhydramine as an antitussive." | 5.07 | Antitussive effects of diphenhydramine on the citric acid aerosol-induced cough response in humans. ( Ciccone, PE; Masurat, T; Packman, EW; Wilson, J, 1991) |
| "Lotussin and linctus diphenhydramine were compared for efficacy and patient preference in fifty patients suffering from post-infective cough." | 5.04 | A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough. ( Matts, SG, 1977) |
| "A double-blind crossover study was conducted to evaluate the antitussive effectiveness of diphenhydramine (DPH) in chornic coughs related to bronchitis, at doses of 25 and 50 mg every 4 hr for four doses." | 5.04 | Antitussive activity of diphenhydramine in chronic cough. ( Lilienfield, LS; Princiotto, JV; Rose, JC, 1976) |
| "Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan." | 4.98 | Honey for acute cough in children. ( Meremikwu, MM; Oduwole, O; Oyo-Ita, A; Udoh, EE, 2018) |
| "Honey may be better than 'no treatment', diphenhydramine and placebo for the symptomatic relief of cough, but it is not better than dextromethorphan." | 4.90 | Honey for acute cough in children. ( Meremikwu, MM; Oduwole, O; Oyo-Ita, A; Udoh, EE, 2014) |
| " Diphenhydramine did not change coughing episodes; the mean difference (MD) of coughing spells per 24 hours was 1." | 4.88 | Symptomatic treatment of the cough in whooping cough. ( Bettiol, S; Harnden, A; Heneghan, CJ; Perera, R; Roberts, NW; Thompson, MJ; Wang, K, 2012) |
| " Diphenhydramine did not change coughing episodes; the mean difference of coughing spells per 24 hours was 1." | 4.86 | Symptomatic treatment of the cough in whooping cough. ( Bettiol, S; Harnden, A; Heneghan, CJ; Perera, R; Roberts, NW; Thompson, MJ, 2010) |
| "Coughing in a child induced by upper respiratory tract infections (URTIs) can be a problem, both for the child and its parents." | 2.84 | Comparison of the Effect of Two Kinds of Iranian Honey and Diphenhydramine on Nocturnal Cough and the Sleep Quality in Coughing Children and Their Parents. ( Allami, A; Ayazi, P; Beyhaghi, T; Esmailzadehha, N; Mahyar, A; Yousef-Zanjani, M, 2017) |
| "Coughing is a prevalent symptom of upper respiratory infections (URIs) that cause disturbance in the sleep of children and their parents." | 2.75 | A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents. ( Mozaffari-Khosravi, H; Mozayan, MR; Shadkam, MN, 2010) |
| "One trial on pertussis immunoglobulin reported a possible mean reduction of -3." | 2.50 | Symptomatic treatment of the cough in whooping cough. ( Bettiol, S; Harnden, A; Heneghan, CJ; Perera, R; Roberts, NW; Thompson, MJ; Wang, K, 2014) |
| "Testing and treatment for cough will vary, depending on the presentation and diagnosis." | 2.46 | The approach to pediatric cough. ( Kelkar, PS; Ramanuja, S, 2010) |
| "Previous research has demonstrated that accidental unsupervised ingestions (AUIs) were responsible for the majority of cough and cold medication (CCM) ingestions leading to significant adverse events (AEs) in children." | 1.72 | Adverse Events Related to Accidental Unintentional Ingestions From Cough and Cold Medications in Children. ( Banner, W; Bond, GR; Dart, RC; Green, JL; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS, 2022) |
| " Diphenhydramine and dextromethorphan dosing errors were the most common cause of medication errors resulting from CCM use." | 1.56 | Medication Errors From Over-the-Counter Cough and Cold Medications in Children. ( Banner, W; Bond, GR; Dart, RC; Green, JL; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (30.77) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 10 (25.64) | 29.6817 |
| 2010's | 12 (30.77) | 24.3611 |
| 2020's | 4 (10.26) | 2.80 |
| Authors | Studies |
|---|---|
| Anibasa, FO | 1 |
| Abuba, T | 1 |
| Dankyau, M | 1 |
| Wang, GS | 2 |
| Reynolds, KM | 3 |
| Banner, W | 3 |
| Bond, GR | 3 |
| Kauffman, RE | 3 |
| Palmer, RB | 3 |
| Paul, IM | 5 |
| Rapp-Olsson, M | 2 |
| Green, JL | 3 |
| Dart, RC | 3 |
| Rehman, H | 2 |
| Ali, SA | 1 |
| Naveed, S | 2 |
| Usmanghani, K | 2 |
| Oduwole, O | 2 |
| Udoh, EE | 2 |
| Oyo-Ita, A | 2 |
| Meremikwu, MM | 2 |
| Wang, K | 2 |
| Bettiol, S | 3 |
| Thompson, MJ | 3 |
| Roberts, NW | 3 |
| Perera, R | 3 |
| Heneghan, CJ | 3 |
| Harnden, A | 3 |
| Dicpinigaitis, PV | 1 |
| Dhar, S | 1 |
| Johnson, A | 1 |
| Gayle, Y | 1 |
| Brew, J | 2 |
| Caparros-Wanderley, W | 1 |
| Birring, SS | 1 |
| Kilbourn, A | 1 |
| Edwards, V | 1 |
| Wilson, R | 1 |
| Morice, AH | 1 |
| Ayazi, P | 1 |
| Mahyar, A | 1 |
| Yousef-Zanjani, M | 1 |
| Allami, A | 1 |
| Esmailzadehha, N | 1 |
| Beyhaghi, T | 1 |
| Shadkam, MN | 1 |
| Mozaffari-Khosravi, H | 1 |
| Mozayan, MR | 1 |
| Ramanuja, S | 1 |
| Kelkar, PS | 1 |
| WAX, J | 1 |
| WINDER, CV | 1 |
| PETERS, G | 1 |
| Yoder, KE | 2 |
| Crowell, KR | 1 |
| Shaffer, ML | 2 |
| McMillan, HS | 1 |
| Carlson, LC | 1 |
| Dilworth, DA | 1 |
| Berlin, CM | 1 |
| Bhatt-Mehta, V | 1 |
| Walburn, J | 1 |
| Skoner, DP | 1 |
| La Tournous, SJ | 1 |
| Björnsdóttir, I | 1 |
| Einarson, TR | 1 |
| Gudmundsson, LS | 1 |
| Einarsdóttir, RA | 1 |
| Jayaram, S | 1 |
| Desai, A | 1 |
| Rispat, G | 1 |
| Burgi, H | 1 |
| Cosnier, D | 1 |
| Duchêne-Marullaz, P | 1 |
| Streichenberger, G | 1 |
| Matts, SG | 1 |
| Lilienfield, LS | 1 |
| Rose, JC | 1 |
| Princiotto, JV | 1 |
| Elberg, M | 1 |
| Packman, EW | 1 |
| Ciccone, PE | 1 |
| Wilson, J | 1 |
| Masurat, T | 1 |
| Jaffe, GV | 1 |
| Grimshaw, JJ | 1 |
| Kleinschmidt, H | 1 |
| Appelt, O | 1 |
| Bäuerlin, H | 1 |
| Reitberger, U | 1 |
| Weilacher, JS | 1 |
| Stoll, HG | 1 |
| Casadio, S | 1 |
| Bruzzese, T | 1 |
| Pala, G | 1 |
| Coppi, G | 1 |
| Turba, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antitussive Effect of a Naturally Flavored, Multi-Component Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo[NCT02062710] | Phase 4 | 22 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Application of Visual Laryngoscope-guided Tracheal Intubation in Lateral Position in Thoracic Surgery:A Prospective, Multicenter, Large Sample, Randomized Controlled Study[NCT05482230] | 300 participants (Anticipated) | Interventional | 2022-09-01 | Not yet recruiting | |||
| A Randomized, Double-blind Study to Evaluate the Efficacy and Tolerability of a Cough Syrup Containing Specific Plant Extracts (Poliflav M.A.) and Honey Versus Placebo in Cough Due to Upper Respiratory Tract Infection[NCT03218696] | 80 participants (Anticipated) | Interventional | 2018-02-28 | Not yet recruiting | |||
| Efficacy & Tolerability of a Specific Plantain,Thyme and Honey Cough Syrup vs Placebo in Child Cough Due to Common Cold[NCT02486835] | 150 participants (Actual) | Interventional | 2015-12-23 | Completed | |||
| Comparison of Supportive Therapies for Symptom Relief From Pediatric Upper Respiratory Infections (URIs)[NCT01814293] | 0 participants (Actual) | Interventional | 2013-05-31 | Withdrawn (stopped due to loss of funding. No data was collected.) | |||
| Randomized, Single Blind, Multicenter Study to Evaluate the Efficacy and Tolerability of Syr. Grintuss Pediatric and Syr. Mucolit in Cough Due to Upper Respiratory Tract Infection in Children[NCT01968434] | Phase 4 | 150 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
increase in C5 (decrease in cough reflex sensitivity). Capsaicin cough challenge involves subjects breathing in incremental doubling concentrations of aerosolized capsaicin, 1 minute apart, until the concentration of capsaicin (micromolar) inducing 5 or more coughs (C5) is reached. (NCT02062710)
Timeframe: 2 hours after study drug administration
| Intervention | log C5 (uM) (Mean) |
|---|---|
| Diphenhydramine/Phenylephrine/Cocoa | 0.97 |
| Dextromethorphan | 0.80 |
| Placebo | 0.57 |
"A validated cough questionnaire measuring 3 aspects of daytime cough (frequency, severity, bothersomeness) on a 7 point Likert scale was used each evening to rate the passed day, as regards these aspects. The scale rates each parameter from 0 (not at all) to 6 (extremely). Every day of the trial is rated. The last evening of the study (D4) the parents rated the passed day by scoring from 0-6 each of the 3 aspects of day cough. The summed score for all aspects gives the combined day cough score. This score, ranging between 0-18, was subtracted from the sum of all aspects, also ranging between 0-18, form the basal day cough score of the day before enrollment (D0). This change is recorded as change in combined day cough score and it refers to the change from D0 to D4. Negative values of the change indicate an improvement in the condition of the patient." (NCT01968434)
Timeframe: 4 nights (onset of trial Night 1 to Night 4) and 3 days
| Intervention | change in combined day cough score (Mean) |
|---|---|
| Protective Cough Syrup | -6.17 |
| Carbocisteine Cough Syrup | -4.54 |
"A validated cough questionnaire measuring 5 aspects of night cough (frequency, severity, bothersomeness, child sleep and parents' sleep) on a 7 point Likert scale was used each morning to rate the passed night. The scale rates each parameter from 0 (not at all) to 6 (extremely). Every night of the trial is rated. The morning after the last night of the study (N4) the parents rated the passed night by scoring from 0-6 each of the 5 aspects of night cough. The summed score for all aspects gives the combined night cough score. This score, ranging between 0-30, was subtracted from the sum of all aspects, also ranging between 0-30, form the basal night cough score of the night before enrollment (N0). This change is recorded as change in combined night cough score and it refers to the change from N0 to N4. Negative values of the change indicate an improvement in the condition of the patient." (NCT01968434)
Timeframe: 4 nights (onset of trial Night 1 to Night 4) and 3 days
| Intervention | change in combined night cough score (Mean) |
|---|---|
| Protective Cough Syrup | -13.92 |
| Carbocisteine Cough Syrup | -9.48 |
"Night cough is most bothersome to the child and family. Cough was measured with a validated questionnaire which asks parents to rate 5 aspects of night cough: frequency, severity, bothersomeness, child sleep and parent sleep according to a 7 point Likert scale, from 0 (not at all) to 6 (extremely). Lower scores indicate a better condition. The morning after the first night of treatment (N1) the parents rated the passed night by scoring from 0-6 each of the 5 aspects of night cough. The sum of scores for all 5 aspects gives the combined night cough score. This score, ranging between 0-30, was subtracted from the sum of all aspects, also ranging between 0-30, form the basal night cough score of the night before enrollment (N0). This change is recorded as change in combined night cough score and it refers to the change from N0 to N1. Negative values of the change indicate an improvement in the condition of the patient." (NCT01968434)
Timeframe: 1 night from before enrollment (N0) to first night after treatment (N1)
| Intervention | change in combined night cough score (Mean) |
|---|---|
| Protective Cough Syrup | -5.16 |
| Carbocisteine Cough Syrup | -1.77 |
7 reviews available for diphenhydramine and Cough
| Article | Year |
|---|---|
Honey for acute cough in children.
Topics: Adolescent; Albuterol; Antitussive Agents; Apitherapy; Bromelains; Bronchodilator Agents; Child; Chi | 2018 |
Symptomatic treatment of the cough in whooping cough.
Topics: Acetates; Adolescent; Adult; Albuterol; Anti-Inflammatory Agents; Bordetella pertussis; Child; Cough | 2014 |
Honey for acute cough in children.
Topics: Adolescent; Antitussive Agents; Apitherapy; Child; Child, Preschool; Cough; Dextromethorphan; Diphen | 2014 |
Symptomatic treatment of the cough in whooping cough.
Topics: Adult; Albuterol; Anti-Inflammatory Agents; Child; Cough; Dexamethasone; Diphenhydramine; Histamine | 2010 |
The approach to pediatric cough.
Topics: Adult; Animals; Antitussive Agents; Asthma; Bronchiectasis; Bronchiolitis; Bronchopneumonia; Child, | 2010 |
Symptomatic treatment of the cough in whooping cough.
Topics: Adult; Albuterol; Anti-Inflammatory Agents; Bordetella pertussis; Child; Cough; Dexamethasone; Diphe | 2012 |
Efficacy of diphenhydramine against cough in humans: a review.
Topics: Cough; Diphenhydramine; Humans | 2007 |
15 trials available for diphenhydramine and Cough
| Article | Year |
|---|---|
Effect of Honey on Cough Symptoms in Children with Upper Respiratory Tract Infection: A Randomised Controlled Trial.
Topics: Antitussive Agents; Child; Cough; Demulcents; Diphenhydramine; Female; Honey; Humans; Male; Respirat | 2022 |
An interquartile relationship between polyherbal extract based lozenges linkus a phase IV comparative randomised control trial.
Topics: Aminophylline; Antitussive Agents; Child; Cough; Diphenhydramine; Female; Humans; Male; Pakistan; Pl | 2017 |
Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection.
Topics: Adult; Antitussive Agents; Capsaicin; Cough; Dextromethorphan; Diphenhydramine; Double-Blind Method; | 2015 |
Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children.
Topics: Age Factors; Aminophylline; Antitussive Agents; Bronchodilator Agents; Child; Child, Preschool; Coug | 2016 |
Rococo study: a real-world evaluation of an over-the-counter medicine in acute cough (a multicentre, randomised, controlled study).
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Ammonium Chloride; Antipruritics; Cacao; | 2017 |
Comparison of the Effect of Two Kinds of Iranian Honey and Diphenhydramine on Nocturnal Cough and the Sleep Quality in Coughing Children and Their Parents.
Topics: Child; Child, Preschool; Cough; Diphenhydramine; Female; Honey; Humans; Infant; Male; Parents; Respi | 2017 |
A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents.
Topics: Antitussive Agents; Apitherapy; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; Female; | 2010 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; D | 2004 |
Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection.
Topics: Adolescent; Antitussive Agents; Child; Cough; Dextromethorphan; Diphenhydramine; Female; Humans; Mal | 2006 |
Efficacy and safety of Ascoril expectorant and other cough formula in the treatment of cough management in paediatric and adult patients--a randomised double-blind comparative trial.
Topics: Adolescent; Adult; Albuterol; Ammonium Chloride; Bromhexine; Child; Child, Preschool; Citrates; Coug | 2000 |
A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough.
Topics: Ammonium Chloride; Antitussive Agents; Chloroform; Citrates; Clinical Trials as Topic; Cough; Dextro | 1977 |
Antitussive activity of diphenhydramine in chronic cough.
Topics: Adult; Aged; Antitussive Agents; Chronic Disease; Clinical Trials as Topic; Cough; Diphenhydramine; | 1976 |
Antitussive effects of diphenhydramine on the citric acid aerosol-induced cough response in humans.
Topics: Administration, Inhalation; Adolescent; Adult; Citrates; Citric Acid; Cough; Diphenhydramine; Double | 1991 |
Benylin expectorant versus actifed expectorant in the treatment of acute cough.
Topics: Adult; Consumer Behavior; Cough; Diphenhydramine; Drug Combinations; Ephedrine; Expectorants; Female | 1985 |
[Attempt to test a new antitussive agent].
Topics: Adolescent; Ammonium Chloride; Antitussive Agents; Child; Child, Preschool; Clinical Trials as Topic | 1974 |
17 other studies available for diphenhydramine and Cough
| Article | Year |
|---|---|
Medication Errors From Over-the-Counter Cough and Cold Medications in Children.
Topics: Child; Child, Preschool; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Utilization; Fe | 2020 |
Adverse Events Related to Accidental Unintentional Ingestions From Cough and Cold Medications in Children.
Topics: Child; Cough; Diphenhydramine; Eating; Hospitalization; Humans; Infant; Nonprescription Drugs; Unite | 2022 |
Adverse events associated with diphenhydramine in children, 2008-2015.
Topics: Adverse Drug Reaction Reporting Systems; Antitussive Agents; Child; Cough; Diphenhydramine; Humans; | 2020 |
Best drugs for what ails you: the brands to buy--and those to skip.
Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha | 2009 |
An antitussive property of diphenhydramine in dogs.
Topics: Animals; Antitussive Agents; Cough; Diphenhydramine; Dogs | 1962 |
Over-the-counter cough and cold medicines: should parents be using them for their children?
Topics: Antitussive Agents; Child; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Humans; Nonprescri | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Antitussive Agents; Cough; Dextromethorphan; Diphenhydramine; Humans; Placebo Effect; Placebos; Sucr | 2004 |
Kids' cough drugs may not work.
Topics: Adult; Antitussive Agents; Child; Cost-Benefit Analysis; Cough; Dextromethorphan; Diphenhydramine; H | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Confounding Factors, Epidemiologic; Cough; | 2005 |
FDA halts sales of some anti-vomiting suppositories...and are cough medications effective in children?
Topics: Adolescent; Antiemetics; Antitussive Agents; Benzamides; Child; Child, Preschool; Cough; Dextrometho | 2007 |
General pharmacological properties of a new non-opiate antitussive: zipeprol (3024 CERM). I. Action on respiratory function and acute toxicity.
Topics: Administration, Oral; Anesthetics, Local; Animals; Antitussive Agents; Bronchi; Cats; Codeine; Cough | 1976 |
American Academy of Pediatrics. Committee on Drugs. Use of codeine- and dextromethorphan-containing cough syrups in pediatrics.
Topics: Adolescent; Animals; Antitussive Agents; Child; Child, Preschool; Codeine; Cough; Dextromethorphan; | 1978 |
[The treatment of dry cough in orhinolaryngology].
Topics: Adolescent; Adult; Child; Child, Preschool; Codeine; Cough; Diphenhydramine; Drug Combinations; Emet | 1976 |
[Treatment of cough in respiratory tract diseases using Tussoretard].
Topics: Adult; Codeine; Cough; Diphenhydramine; Drug Combinations; Ephedrine; Female; Humans; Middle Aged; N | 1972 |
[Cough and its treatment with a new cough-blocking drug].
Topics: Animals; Antitussive Agents; Cough; Diphenhydramine; Drug Combinations; Humans; Mice; Oxadiazoles; P | 1972 |
[Cough suppression as a causative problem of therapeutic measures].
Topics: Cough; Diphenhydramine; Drug Synergism; Humans; Oxadiazoles | 1971 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chem | 1966 |