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diphenhydramine and Complex Regional Pain Syndromes

diphenhydramine has been researched along with Complex Regional Pain Syndromes in 1 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)

Research Excerpts

ExcerptRelevanceReference
"Intravenous lidocaine and diphenhydramine had no significant effect on the cool, warm, or cold pain thresholds."9.09Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. ( Gerayli, A; Leung, AY; Ridgeway, BM; Wallace, MS; Yaksh, TL, 2000)
"Intravenous lidocaine and diphenhydramine had no significant effect on the cool, warm, or cold pain thresholds."5.09Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. ( Gerayli, A; Leung, AY; Ridgeway, BM; Wallace, MS; Yaksh, TL, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wallace, MS1
Ridgeway, BM1
Leung, AY1
Gerayli, A1
Yaksh, TL1

Trials

1 trial available for diphenhydramine and Complex Regional Pain Syndromes

ArticleYear
Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II.
    Anesthesiology, 2000, Volume: 92, Issue:1

    Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Cold Temperature; Complex Regional Pain Syndromes;

2000