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diphenhydramine and Common Cold

diphenhydramine has been researched along with Common Cold in 10 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Common Cold: A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.

Research Excerpts

ExcerptRelevanceReference
"In a five-day, randomized, double-blind study, the efficacy and safety of a syrup containing a combination of azatadine maleate, pseudoephedrine sulfate, and dextromethorphan hydrobromide (SCH 399 syrup) were compared with those of an expectorant containing the antihistamine diphenhydramine hydrochloride in 60 children with symptoms of the common cold and associated cough."5.05Therapeutic approaches to the common cold in children. ( Weippl, G, 1984)
" Diphenhydramine and dextromethorphan dosing errors were the most common cause of medication errors resulting from CCM use."1.56Medication Errors From Over-the-Counter Cough and Cold Medications in Children. ( Banner, W; Bond, GR; Dart, RC; Green, JL; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS, 2020)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Wang, GS1
Reynolds, KM1
Banner, W1
Bond, GR1
Kauffman, RE1
Palmer, RB1
Paul, IM1
Rapp-Olsson, M1
Green, JL1
Dart, RC1
BLASS, G1
ROSSIER, M1
Bhatt-Mehta, V1
Dong, Y1
Chen, X2
Chen, Y1
Hu, Z1
Weippl, G1
Middleton, RS1
Karch, AM1
Karch, FE1
Gaffey, MJ1
Gwaltney, JM1
Sastre, A1
Dressler, WE1
Sorrentino, JV1
Hayden, FG1

Trials

3 trials available for diphenhydramine and Common Cold

ArticleYear
Therapeutic approaches to the common cold in children.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Antitussive Agents; Child; Child, Preschool; Clinical Trials as Topic; Common Cold; Cyproheptadine;

1984
Double blind trial in general practice comparing the efficacy of "Benylin Day and Night" and paracetamol in the treatment of the common cold.
    The British journal of clinical practice, 1981, Volume: 35, Issue:9

    Topics: Acetaminophen; Adolescent; Adult; Aged; Clinical Trials as Topic; Common Cold; Diphenhydramine; Doub

1981
Intranasally and orally administered antihistamine treatment of experimental rhinovirus colds.
    The American review of respiratory disease, 1987, Volume: 136, Issue:3

    Topics: Administration, Intranasal; Administration, Oral; Adult; Chlorpheniramine; Clinical Trials as Topic;

1987

Other Studies

7 other studies available for diphenhydramine and Common Cold

ArticleYear
Medication Errors From Over-the-Counter Cough and Cold Medications in Children.
    Academic pediatrics, 2020, Volume: 20, Issue:3

    Topics: Child; Child, Preschool; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Utilization; Fe

2020
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha

2009
[Therapy & prevention of colds & catarrhal diseases].
    Deutsches medizinisches Journal, 1957, Jul-15, Volume: 8, Issue:7

    Topics: Biomedical Research; Common Cold; Diphenhydramine; Humans; Respiratory System; Respiratory Tract Dis

1957
[INDICATIONS, THERAPEUTIC EFFICACY AND TOLERANCE OF AN ANTIHISTAMINIC SYNERGISM (DIVAHISTINE)].
    Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20

    Topics: Ascorbic Acid; Caffeine; Common Cold; Diphenhydramine; Humans; Immune Tolerance; Nasal Decongestants

1963
Over-the-counter cough and cold medicines: should parents be using them for their children?
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:11

    Topics: Antitussive Agents; Child; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Humans; Nonprescri

2004
Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-01, Volume: 39, Issue:1-2

    Topics: Chlorpheniramine; Common Cold; Dextromethorphan; Diphenhydramine; Electrophoresis, Capillary; Ephedr

2005
Let the user beware. OTC drugs aren't necessarily 'safe when taken as directed.'.
    The American journal of nursing, 2001, Volume: 101, Issue:2

    Topics: Acetaminophen; Adult; Common Cold; Diphenhydramine; Drug Combinations; Drug Overdose; Female; Humans

2001