diphenhydramine has been researched along with Coma in 8 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flumazenil is a competitive antagonist with specific action at the central benzodiazepine receptor." | 5.32 | Reversal of an antihistamine-induced coma with flumazenil. ( Cebrero, M; García-Frías, E; Gónzalez-Santiago, P; Lassaletta, A; Martino, R; Torrijos, C, 2004) |
| "This report describes the first case of an adult to survive all the major complications of diphenhydramine hydrochloride overdose, including hyperpyrexia, status epilepticus, coma, and cardiac arrhythmias." | 3.67 | Survival in complicated diphenhydramine overdose. ( Cox, PM; D'Amato, SL; Rinder, CS; Rinder, HM, 1988) |
| "Flumazenil is a competitive antagonist with specific action at the central benzodiazepine receptor." | 1.32 | Reversal of an antihistamine-induced coma with flumazenil. ( Cebrero, M; García-Frías, E; Gónzalez-Santiago, P; Lassaletta, A; Martino, R; Torrijos, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Irioka, T | 1 |
| Yamanami, A | 1 |
| Uchida, N | 1 |
| Iwase, M | 1 |
| Yasuhara, H | 1 |
| Mizusawa, H | 1 |
| Fridman, V | 1 |
| Galetta, SL | 1 |
| Pruitt, AA | 1 |
| Levine, JM | 1 |
| Lassaletta, A | 1 |
| Martino, R | 1 |
| Gónzalez-Santiago, P | 1 |
| Torrijos, C | 1 |
| Cebrero, M | 1 |
| García-Frías, E | 1 |
| Goodfellow, LM | 1 |
| Knight, ME | 1 |
| Roberts, RJ | 1 |
| Rinder, CS | 1 |
| D'Amato, SL | 1 |
| Rinder, HM | 1 |
| Cox, PM | 1 |
| Collins, JV | 1 |
| Townsend, J | 1 |
| Harris, PW | 1 |
| Clark, TJ | 1 |
| Goulding, R | 1 |
| Matthew, H | 1 |
| Proudfoot, AT | 1 |
| Brown, SS | 1 |
| Smith, AC | 1 |
1 review available for diphenhydramine and Coma
| Article | Year |
|---|---|
Phenothiazine and butyrophenone intoxication in children.
Topics: Absorption; Adolescent; Basal Ganglia Diseases; Benztropine; Butyrophenones; Cardiovascular System; | 1986 |
7 other studies available for diphenhydramine and Coma
| Article | Year |
|---|---|
Opsoclonus caused by diphenhydramine self-poisoning.
Topics: Autonomic Nervous System Diseases; Coma; Diphenhydramine; Humans; Hypnotics and Sedatives; Male; Ocu | 2009 |
MRI findings associated with acute liver failure.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Brain; Brain Edema; Coma; Diphenhydramine; Hepatic E | 2009 |
Reversal of an antihistamine-induced coma with flumazenil.
Topics: Child Abuse; Coma; Diphenhydramine; Flumazenil; GABA-A Receptor Antagonists; Histamine H1 Antagonist | 2004 |
Action stat. Adverse reaction to benadryl.
Topics: Adult; Amoxicillin; Anti-Allergic Agents; Coma; Diphenhydramine; Drug Eruptions; Emergency Nursing; | 1996 |
Survival in complicated diphenhydramine overdose.
Topics: Adult; Arrhythmias, Cardiac; Coma; Diphenhydramine; Female; Fever; Humans; Nonprescription Drugs; Ph | 1988 |
Plasma-11-hydroxycorticosteroid levels in drug-induced coma.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Amitriptyline; Barbiturates; Blood Pressure; Body Temperatu | 1971 |
Mandrax poisoning: conservative management of 116 patients.
Topics: Adolescent; Adult; Aged; Coma; Diphenhydramine; England; Female; Humans; Male; Methaqualone; Middle | 1968 |