Page last updated: 2024-10-26

diphenhydramine and Catatonia

diphenhydramine has been researched along with Catatonia in 3 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Catatonia: A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)

Research Excerpts

ExcerptRelevanceReference
" The catatonia was induced by perphenazine with a concomitant and remarkable increase in the brain histamine level."7.65The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine. ( Chopra, YM; Dandiya, PC, 1974)
" The catatonia was induced by perphenazine with a concomitant and remarkable increase in the brain histamine level."3.65The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine. ( Chopra, YM; Dandiya, PC, 1974)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chopra, YM2
Dandiya, PC3
Patni, SK1

Other Studies

3 other studies available for diphenhydramine and Catatonia

ArticleYear
The relative role of brain acetylcholine and histamine in perphenazine catatonia and influence of antidepressants and diphenhydramine alone and in combination.
    Neuropharmacology, 1975, Volume: 14, Issue:8

    Topics: Acetylcholine; Animals; Antidepressive Agents; Brain; Brain Chemistry; Catatonia; Diphenhydramine; D

1975
The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine.
    Pharmacology, 1974, Volume: 12, Issue:6

    Topics: Animals; Antidepressive Agents; Brain; Brain Chemistry; Catatonia; Diphenhydramine; Drug Synergism;

1974
The influence of monoamine oxidase inhibitors and some other antidepressants on the anti-parkinsonian activity of sub-effective doses of diphenylhydramine in rats and mice.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:3

    Topics: Animals; Antidepressive Agents; Catatonia; Diphenhydramine; Humans; Mice; Monoamine Oxidase Inhibito

1972