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diphenhydramine and Canine Diseases

diphenhydramine has been researched along with Canine Diseases in 12 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research Excerpts

ExcerptRelevanceReference
"To report the outcome of treatment of uncomplicated allergic reactions in dogs with diphenhydramine vs diphenhydramine plus glucocorticoid and to determine the incidence rate of uncomplicated allergic reactions DESIGN: Retrospective study between January 1, 2012 and August 15, 2018."9.41Retrospective review of diphenhydramine versus diphenhydramine plus glucocorticoid for treatment of uncomplicated allergic reaction in dogs. ( Helgeson, ME; Kierski, KR; Pigott, AM, 2021)
"To determine and compare the effects oral of DPH and cetirizine on the immediate- and late-phase cutaneous allergic reactions in healthy dogs."9.34Effect of diphenhydramine and cetirizine on immediate and late-phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study. ( Banovic, F; Blubaugh, A; Denley, T; Lemo, N; Papich, MG; Scheibe, I, 2020)
"To report the outcome of treatment of uncomplicated allergic reactions in dogs with diphenhydramine vs diphenhydramine plus glucocorticoid and to determine the incidence rate of uncomplicated allergic reactions DESIGN: Retrospective study between January 1, 2012 and August 15, 2018."5.41Retrospective review of diphenhydramine versus diphenhydramine plus glucocorticoid for treatment of uncomplicated allergic reaction in dogs. ( Helgeson, ME; Kierski, KR; Pigott, AM, 2021)
"To determine and compare the effects oral of DPH and cetirizine on the immediate- and late-phase cutaneous allergic reactions in healthy dogs."5.34Effect of diphenhydramine and cetirizine on immediate and late-phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study. ( Banovic, F; Blubaugh, A; Denley, T; Lemo, N; Papich, MG; Scheibe, I, 2020)
" Gastric plasmacytoma with lymph node metastasis was diagnosed by histologic and immunoperoxidase methods, and chemotherapy was initiated with doxorubicin hydrochloride and diphenhydramine hydrochloride."3.68Gastric extramedullary plasmacytoma in a dog. ( Altman, NH; Brunnert, SR; Dee, LA; Herron, AJ, 1992)
" During pentobarbital anesthesia, 2 pulmonary hemodynamic studies were conducted on each dog with a sequence of baseline, hypoxia with FlO2 = 10%, hyperoxia with FlO2 = 100%, a second baseline, treatment with either diphenhydramine (D) or cimetidine (C), and another hypoxia."3.68Postadulticide pulmonary hypertension of canine heartworm disease: successful treatment with oxygen and failure of antihistamines. ( Rawlings, CA; Tackett, RL, 1990)
"Diphenhydramine exposure was by ingestion for 581 (93."1.43Diphenhydramine exposure in dogs: 621 cases (2008-2013). ( Dorman, DC; Wismer, TA; Worth, AC, 2016)
"Urticaria pigmentosa is a rare dermatologic syndrome in humans, cats, and dogs."1.42Urticaria pigmentosa-like disease in a dog. ( Gram, DW; Pariser, MS, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Banovic, F1
Denley, T1
Blubaugh, A1
Scheibe, I1
Lemo, N1
Papich, MG1
Helgeson, ME1
Pigott, AM1
Kierski, KR1
Sanchez, A1
Valverde, A1
Sinclair, M1
Mosley, C1
Singh, A1
Mutsaers, AJ1
Hanna, B1
Johnson, R1
Gu, Y1
Beaudoin-Kimble, M1
Buchweitz, JP1
Raverty, SA1
Johnson, MB1
Lehner, AF1
Pariser, MS1
Gram, DW1
Worth, AC1
Wismer, TA1
Dorman, DC1
BĂ©langer, C1
Visser, LC1
Stern, JA1
Jang, HY1
Parent, JM1
Hagen, C1
Colwell, E1
Rist, PM1
Murphy, N1
Burton, S1
Conboy, G1
Ward, AB1
Cross, JR1
Glass, EN1
de Lahunta, A1
Zur, G1
Ihrke, PJ1
White, SD1
Kass, PH1
Brunnert, SR1
Dee, LA1
Herron, AJ1
Altman, NH1
Rawlings, CA1
Tackett, RL1

Trials

3 trials available for diphenhydramine and Canine Diseases

ArticleYear
Effect of diphenhydramine and cetirizine on immediate and late-phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study.
    Veterinary dermatology, 2020, Volume: 31, Issue:4

    Topics: Animals; Cetirizine; Cross-Over Studies; Diphenhydramine; Dog Diseases; Dogs; Double-Blind Method; H

2020
Retrospective review of diphenhydramine versus diphenhydramine plus glucocorticoid for treatment of uncomplicated allergic reaction in dogs.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2021, Volume: 31, Issue:3

    Topics: Animals; Dexamethasone; Diphenhydramine; Dog Diseases; Dogs; Drug Therapy, Combination; Glucocortico

2021
Antihistaminic and cardiorespiratory effects of diphenhydramine hydrochloride in anesthetized dogs undergoing excision of mast cell tumors.
    Journal of the American Veterinary Medical Association, 2017, Oct-01, Volume: 251, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Diphenhydramine; Dog Diseases; Dogs; Female; Heart

2017

Other Studies

9 other studies available for diphenhydramine and Canine Diseases

ArticleYear
Fatal diphenhydramine poisoning in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2014, Volume: 55, Issue:11

    Topics: Animals; Diagnosis, Differential; Diphenhydramine; Dog Diseases; Dogs; Drug Overdose; Ethanol; Hista

2014
Urticaria pigmentosa-like disease in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:3

    Topics: Animals; Anti-Allergic Agents; Anti-Ulcer Agents; Cetirizine; Diphenhydramine; Dog Diseases; Dogs; F

2015
Diphenhydramine exposure in dogs: 621 cases (2008-2013).
    Journal of the American Veterinary Medical Association, 2016, Jul-01, Volume: 249, Issue:1

    Topics: Animals; Anti-Allergic Agents; Diphenhydramine; Dog Diseases; Dogs; Female; Illinois; Male; Poison C

2016
ECG of the Month.
    Journal of the American Veterinary Medical Association, 2016, Nov-15, Volume: 249, Issue:10

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Bees; Diphenhydramine; Dog Diseases; Dogs; Electrocardio

2016
Paradoxical vestibular syndrome in a dog from western Newfoundland infected with French heartworm
    The Canadian veterinary journal = La revue veterinaire canadienne, 2016, Volume: 57, Issue:12

    Topics: Amines; Analgesics; Angiostrongylus; Animals; Anthelmintics; Cyclohexanecarboxylic Acids; Dexamethas

2016
What is your diagnosis? Intracranial parasitic migration.
    Journal of the American Veterinary Medical Association, 2012, Sep-15, Volume: 241, Issue:6

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Brain Diseases; Central Nervous System Parasitic I

2012
Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).
    Veterinary therapeutics : research in applied veterinary medicine, 2002,Spring, Volume: 3, Issue:1

    Topics: Allergens; Animals; Chlorpheniramine; Clemastine; Dermatitis, Atopic; Diphenhydramine; Dog Diseases;

2002
Gastric extramedullary plasmacytoma in a dog.
    Journal of the American Veterinary Medical Association, 1992, May-15, Volume: 200, Issue:10

    Topics: Animals; Chemotherapy, Adjuvant; Diphenhydramine; Dog Diseases; Dogs; Doxorubicin; Female; Gastrecto

1992
Postadulticide pulmonary hypertension of canine heartworm disease: successful treatment with oxygen and failure of antihistamines.
    American journal of veterinary research, 1990, Volume: 51, Issue:10

    Topics: Animals; Arsenamide; Blood Pressure; Cimetidine; Diphenhydramine; Dirofilariasis; Dog Diseases; Dogs

1990