diphenhydramine has been researched along with Brugada Syndrome in 2 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diphenhydramine (DPH) is a first-generation antihistamine, which is useful in treating allergic reaction, and is usually considered innocuous." | 5.40 | Diphenhydramine dependence through deep intramuscular injection resulting in myonecrosis and prolonged QT interval. ( Chang, CC; Chen, CY; Chen, TY; Kuo, SC; Lin, TP; Yeh, YW, 2014) |
| "Diphenhydramine (DPH) is a first-generation antihistamine, which is useful in treating allergic reaction, and is usually considered innocuous." | 1.40 | Diphenhydramine dependence through deep intramuscular injection resulting in myonecrosis and prolonged QT interval. ( Chang, CC; Chen, CY; Chen, TY; Kuo, SC; Lin, TP; Yeh, YW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, TY | 1 |
| Yeh, YW | 1 |
| Kuo, SC | 1 |
| Chen, CY | 1 |
| Lin, TP | 1 |
| Chang, CC | 1 |
| Levine, M | 1 |
| Lovecchio, F | 1 |
2 other studies available for diphenhydramine and Brugada Syndrome
| Article | Year |
|---|---|
Diphenhydramine dependence through deep intramuscular injection resulting in myonecrosis and prolonged QT interval.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Depression; Diphenhydrami | 2014 |
Diphenhydramine-induced Brugada pattern.
Topics: Adult; Brugada Syndrome; Cholinergic Antagonists; Diphenhydramine; Electrocardiography; Humans; Male | 2010 |