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diphenhydramine and Brain Edema

diphenhydramine has been researched along with Brain Edema in 4 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Diphenhydramine is a drug readily available over the counter in the form of capsules, tablets, and syrup used for allergy relief."1.35Death of a child from topical diphenhydramine. ( Turner, JW, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fridman, V1
Galetta, SL1
Pruitt, AA1
Levine, JM1
Turner, JW1
Vycudilik, W1
Pollak, S1
McManus, WF1
Hunt, JL1
Pruitt, BA1

Other Studies

4 other studies available for diphenhydramine and Brain Edema

ArticleYear
MRI findings associated with acute liver failure.
    Neurology, 2009, Jun-16, Volume: 72, Issue:24

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Brain; Brain Edema; Coma; Diphenhydramine; Hepatic E

2009
Death of a child from topical diphenhydramine.
    The American journal of forensic medicine and pathology, 2009, Volume: 30, Issue:4

    Topics: Administration, Topical; Brain Edema; Diphenhydramine; Eczema; Forensic Pathology; Forensic Toxicolo

2009
[Detection of diphenhydramine in autolytic brain tissue in poison-induced brain death syndrome].
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1985, Volume: 95, Issue:2

    Topics: Autolysis; Blood-Brain Barrier; Brain; Brain Death; Brain Edema; Diphenhydramine; Female; Gas Chroma

1985
Postburn convulsive disorders in children.
    The Journal of trauma, 1974, Volume: 14, Issue:5

    Topics: Adolescent; Age Factors; Autopsy; Brain Edema; Burns; Carbenicillin; Child; Child, Preschool; Diphen

1974