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diphenhydramine and Bordetella pertussis Infection, Respiratory

diphenhydramine has been researched along with Bordetella pertussis Infection, Respiratory in 6 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research Excerpts

ExcerptRelevanceReference
" Diphenhydramine did not change coughing episodes; the mean difference (MD) of coughing spells per 24 hours was 1."4.88Symptomatic treatment of the cough in whooping cough. ( Bettiol, S; Harnden, A; Heneghan, CJ; Perera, R; Roberts, NW; Thompson, MJ; Wang, K, 2012)
" Diphenhydramine did not change coughing episodes; the mean difference of coughing spells per 24 hours was 1."4.86Symptomatic treatment of the cough in whooping cough. ( Bettiol, S; Harnden, A; Heneghan, CJ; Perera, R; Roberts, NW; Thompson, MJ, 2010)
"One trial on pertussis immunoglobulin reported a possible mean reduction of -3."2.50Symptomatic treatment of the cough in whooping cough. ( Bettiol, S; Harnden, A; Heneghan, CJ; Perera, R; Roberts, NW; Thompson, MJ; Wang, K, 2014)
"Whooping cough is an important cause of childhood morbidity and mortality."2.44WITHDRAWN: Symptomatic treatment of the cough in whooping cough. ( Pillay-Van Wyk, V; Swingler, GH, 2008)
"Whooping cough is an important cause of childhood morbidity and mortality."2.42Symptomatic treatment of the cough in whooping cough. ( Pillay, V; Swingler, G, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, K2
Bettiol, S3
Thompson, MJ3
Roberts, NW3
Perera, R3
Heneghan, CJ3
Harnden, A3
Pillay-Van Wyk, V1
Swingler, GH1
Pillay, V1
Swingler, G1
Danzon, A1
Lacroix, J1
Infante-Rivard, C1
Chicoine, L1

Reviews

5 reviews available for diphenhydramine and Bordetella pertussis Infection, Respiratory

ArticleYear
Symptomatic treatment of the cough in whooping cough.
    The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9

    Topics: Acetates; Adolescent; Adult; Albuterol; Anti-Inflammatory Agents; Bordetella pertussis; Child; Cough

2014
WITHDRAWN: Symptomatic treatment of the cough in whooping cough.
    The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4

    Topics: Adult; Albuterol; Child; Dexamethasone; Diphenhydramine; Histamine H1 Antagonists; Humans; Immunoglo

2008
Symptomatic treatment of the cough in whooping cough.
    The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1

    Topics: Adult; Albuterol; Anti-Inflammatory Agents; Child; Cough; Dexamethasone; Diphenhydramine; Histamine

2010
Symptomatic treatment of the cough in whooping cough.
    The Cochrane database of systematic reviews, 2012, May-16, Issue:5

    Topics: Adult; Albuterol; Anti-Inflammatory Agents; Bordetella pertussis; Child; Cough; Dexamethasone; Diphe

2012
Symptomatic treatment of the cough in whooping cough.
    The Cochrane database of systematic reviews, 2003, Issue:4

    Topics: Adult; Albuterol; Child; Dexamethasone; Diphenhydramine; Histamine H1 Antagonists; Humans; Immunoglo

2003

Trials

1 trial available for diphenhydramine and Bordetella pertussis Infection, Respiratory

ArticleYear
A double-blind clinical trial on diphenhydramine in pertussis.
    Acta paediatrica Scandinavica, 1988, Volume: 77, Issue:4

    Topics: Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Humans; Infant; Prospective Studies;

1988