diphenhydramine has been researched along with Basal Ganglia Diseases in 20 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diphenhydramine (DPH) is most commonly used via oral, topical, intramuscular (IM) and intravenous (IV) routes for the palliation of pruritus, treatment of extrapyramidal symptoms, management of parkinsonism and for allergic reactions." | 3.85 | Safe Use of Subcutaneous Diphenhydramine in the Inpatient Hospice Unit. ( Chen, A; Cooney, GA; Gonzalez, F; Hickey, T; Levene, R; Loquias, EJ; Roshan, R; Zelhof, R, 2017) |
| ", migraines) in the emergency department, but can cause serious adverse effects." | 2.72 | Prophylactic Administration of Diphenhydramine to Reduce Neuroleptic Side Effects in the Acute Care Setting: A Systematic Review and Meta-Analysis. ( Alain, J; Berthelot, S; Mokhtari, A; Yip, O, 2021) |
| "Pediatric migraine is a common, chronic, and disabling neurological disorder in children and adolescents." | 2.66 | Intravenous Migraine Treatment in Children and Adolescents. ( Hershey, AD; Kabbouche, M; Maconochie, I; Murphy, B; Qaiser, S; Werner, K, 2020) |
| "Baclofen and oxazepam were prescribed secondary to right-sided hemiparesis contractures." | 1.34 | Potential aripiprazole-mediated extrapyramidal symptoms in an adult with developmental disabilities. ( Brahm, NC; Brown, RC; McElwain, DL, 2007) |
| " Before studying the efficacy of MCP as an antiemetic in children, we first had to establish the safe dose range." | 1.27 | Metoclopramide: dose-related toxicity and preliminary antiemetic studies in children receiving cancer chemotherapy. ( Allen, JC; Gralla, R; Kellick, M; Reilly, L; Young, C, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Werner, K | 1 |
| Qaiser, S | 1 |
| Kabbouche, M | 1 |
| Murphy, B | 1 |
| Maconochie, I | 1 |
| Hershey, AD | 1 |
| Mokhtari, A | 1 |
| Yip, O | 1 |
| Alain, J | 1 |
| Berthelot, S | 1 |
| D'Souza, RS | 1 |
| Mercogliano, C | 1 |
| Ojukwu, E | 1 |
| D'Souza, S | 1 |
| Singles, A | 1 |
| Modi, J | 1 |
| Short, A | 1 |
| Donato, A | 1 |
| Chen, A | 1 |
| Loquias, EJ | 1 |
| Roshan, R | 1 |
| Levene, R | 1 |
| Zelhof, R | 1 |
| Hickey, T | 1 |
| Cooney, GA | 1 |
| Gonzalez, F | 1 |
| FANNING, WJ | 1 |
| Ott, HW | 1 |
| Biebl, W | 1 |
| Donnemiller, E | 1 |
| Moncayo, R | 1 |
| Brashier, M | 1 |
| Brahm, NC | 1 |
| McElwain, DL | 1 |
| Brown, RC | 1 |
| Dahiya, U | 1 |
| Noronha, P | 1 |
| Miglets, AW | 1 |
| Racey, G | 1 |
| Hoffer, JL | 1 |
| Witschy, JK | 1 |
| Redmond, FC | 1 |
| Cheslik, TA | 1 |
| Erramouspe, J | 1 |
| Isabelle, C | 1 |
| Warner, A | 1 |
| Markowitz, JS | 1 |
| McLeod-Bryant, S | 1 |
| Jackson, CW | 1 |
| Chiles, JA | 1 |
| Lavenstein, BL | 1 |
| Cantor, FK | 1 |
| Yosselson, S | 1 |
| Kaplan, A | 1 |
| Knight, ME | 1 |
| Roberts, RJ | 1 |
| Allen, JC | 1 |
| Gralla, R | 1 |
| Reilly, L | 1 |
| Kellick, M | 1 |
| Young, C | 1 |
| Levy, W | 1 |
| Wisniewski, K | 1 |
4 reviews available for diphenhydramine and Basal Ganglia Diseases
| Article | Year |
|---|---|
Intravenous Migraine Treatment in Children and Adolescents.
Topics: Administration, Intravenous; Adolescent; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Inflammat | 2020 |
Prophylactic Administration of Diphenhydramine to Reduce Neuroleptic Side Effects in the Acute Care Setting: A Systematic Review and Meta-Analysis.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Diphenhydramine; Drug-Related Side Effects and Adverse | 2021 |
Effects of prophylactic anticholinergic medications to decrease extrapyramidal side effects in patients taking acute antiemetic drugs: a systematic review and meta-analysis.
Topics: Antiemetics; Basal Ganglia Diseases; Cholinergic Antagonists; Diphenhydramine; Humans | 2018 |
Phenothiazine and butyrophenone intoxication in children.
Topics: Absorption; Adolescent; Basal Ganglia Diseases; Benztropine; Butyrophenones; Cardiovascular System; | 1986 |
16 other studies available for diphenhydramine and Basal Ganglia Diseases
| Article | Year |
|---|---|
Safe Use of Subcutaneous Diphenhydramine in the Inpatient Hospice Unit.
Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia Diseases; Diphenhydramine; Female; Hospices; Humans; I | 2017 |
Extrapyramidal symptoms associated with the administration of trifluoperazine: report of a case treated with diphenhydramine.
Topics: Basal Ganglia Diseases; Diphenhydramine; Disease; Extrapyramidal Tracts; Tranquilizing Agents; Trifl | 1961 |
Imaging of the corpus striatum without any activity at 192 MBq 18F-fluorodeoxyglucose PET after intoxication.
Topics: Adult; Basal Ganglia Diseases; Brain Mapping; Corpus Striatum; Diphenhydramine; Female; Fluorodeoxyg | 2005 |
Fluphenazine-induced extrapyramidal side effects in a horse.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Diphenhydramine; Extrapyramidal Tracts; Fluph | 2006 |
Potential aripiprazole-mediated extrapyramidal symptoms in an adult with developmental disabilities.
Topics: Adult; Algorithms; Antipsychotic Agents; Aripiprazole; Baclofen; Basal Ganglia Diseases; Citalopram; | 2007 |
Drug-induced acute dystonic reactions in children. Alternatives to diphenhydramine therapy.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Child; Child, Preschool; Creatine Kinase; | 1984 |
Phenothiazine induced lingual trauma.
Topics: Adult; Basal Ganglia Diseases; Diphenhydramine; Edema; Female; Humans; Thioridazine; Tongue | 1983 |
Extrapyramidal reaction to fluphenazine potentiated by thyrotoxicosis.
Topics: Basal Ganglia Diseases; Diphenhydramine; Drug Therapy, Combination; Fluphenazine; Humans; Hyperthyro | 1981 |
Extrapyramidal symptoms following accidental ingestion of risperidone in a child.
Topics: Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Child, Preschool; Diphenhydramin | 1996 |
Long-term heavy use of diphenhydramine without anticholinergic delirium.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Cholinergic Antagonists; Diphenhydramine; Human | 1999 |
Cost savings with intramuscular anticholinergics.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Cholinergic Antagonists; Cost Savings; Di | 2001 |
Extrapyramidal reactions in adolescents treated with high-potency antipsychotics.
Topics: Adolescent; Age Factors; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Diphenh | 1978 |
Acute dystonia. An unusal reaction to diphenhydramine.
Topics: Acute Disease; Age Factors; Basal Ganglia Diseases; Diphenhydramine; Humans; Infant; Male | 1976 |
Letter: Neurotoxic reaction to haloperidol in a thyrotoxic patient.
Topics: Adult; Basal Ganglia Diseases; Diphenhydramine; Female; Haloperidol; Humans; Hyperthyroidism; Trihex | 1975 |
Metoclopramide: dose-related toxicity and preliminary antiemetic studies in children receiving cancer chemotherapy.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antineoplastic Agents; Basal Ganglia Diseases; Child; Di | 1985 |
Chlorpromazine causing extrapyramidal dysfunction in newborn infant of psychotic mother.
Topics: Basal Ganglia Diseases; Chlorpromazine; Diphenhydramine; Female; Humans; Infant, Newborn; Infant, Ne | 1974 |