diphenhydramine has been researched along with Atopic Hypersensitivity in 27 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 73-year-old Caucasian woman with metastatic bladder cancer developed hives, itching, difficulty in breathing, and general ill-feeling during the first 10 min of her first infusion of paclitaxel." | 3.74 | Cross-reactivity between paclitaxel and hazelnut: a case report. ( Bander, R; Bukacel, DG; Ibrahim, RB, 2007) |
| "Diphenhydramine is often the treatment of choice for acute urticarial or allergic reactions despite its adverse effects of sedation and impairment." | 2.73 | Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine. ( Casale, TB; Jones, DH; Romero, FA, 2008) |
| "Diphenhydramine treatment alone partially inhibited the histologic intensity of LPR in a dose-dependent manner." | 1.27 | The biologic activity of mast cell granules. V. The effects of antihistamine treatment on rat cutaneous early- and late-phase allergic reactions. ( Barr, L; Guthman, DA; Kaliner, M; Lemanske, RF, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nath, P | 1 |
| Basher, A | 1 |
| Harada, M | 1 |
| Sarkar, S | 1 |
| Selim, S | 1 |
| Maude, RJ | 1 |
| Noiri, E | 1 |
| Faiz, A | 1 |
| Jones, DH | 1 |
| Romero, FA | 1 |
| Casale, TB | 1 |
| Bukacel, DG | 1 |
| Bander, R | 1 |
| Ibrahim, RB | 1 |
| Johnson, HG | 1 |
| McNee, ML | 1 |
| Bach, MK | 1 |
| Smith, HW | 1 |
| Lemanske, RF | 1 |
| Barr, L | 1 |
| Guthman, DA | 1 |
| Kaliner, M | 1 |
| Becker, DE | 1 |
| Vuurman, EF | 1 |
| van Veggel, LM | 1 |
| Uiterwijk, MM | 1 |
| Leutner, D | 1 |
| O'Hanlon, JF | 1 |
| Moffitt, JE | 1 |
| Yates, AB | 1 |
| Stafford, CT | 1 |
| Biron, CR | 1 |
| Inagaki, N | 1 |
| Sakurai, T | 1 |
| Abe, T | 1 |
| Musoh, K | 1 |
| Kawasaki, H | 1 |
| Tsunematsu, M | 1 |
| Nagai, H | 1 |
| Perez, JA | 1 |
| Kleier, DJ | 1 |
| Shibilski, K | 1 |
| Kodani, M | 1 |
| Sakata, N | 1 |
| Takano, Y | 1 |
| Kamiya, H | 1 |
| Katsuragi, T | 1 |
| Hugli, TE | 1 |
| Abe, M | 1 |
| Lohiya, GS | 1 |
| Brown, DL | 1 |
| Login, IS | 1 |
| Borish, L | 1 |
| Powers, PL | 1 |
| Lamkin, N | 1 |
| Lieberman, P | 2 |
| Shereff, R | 1 |
| Rosenberg, EW | 2 |
| Robinson, H | 2 |
| Greenberger, P | 1 |
| Patterson, R | 2 |
| Soskin, IaM | 1 |
| Kruglikova, LI | 1 |
| Maibach, HI | 1 |
| Johnson, HL | 1 |
| Loeb, JA | 1 |
| Herold, KC | 1 |
| Barton, KP | 1 |
| Robinson, LE | 1 |
| Jaspan, JB | 1 |
| Griffen, D | 1 |
| Donovan, JW | 1 |
| Durie, BG | 1 |
| Peters, GA | 1 |
| Talbot, CH | 1 |
| Booth, BH | 1 |
| Reichert, EF | 1 |
| Bassett, PA | 1 |
| Shereff, RH | 1 |
| Harwell, W | 1 |
| Lockey, RF | 1 |
| Cowdrey, SC | 1 |
2 reviews available for diphenhydramine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Management of immediate allergic reactions.
Topics: Adrenergic Agonists; Anaphylaxis; Anti-Allergic Agents; Dental Care; Dental Offices; Diphenhydramine | 1995 |
Allergy to insect stings. A need for improved preventive management.
Topics: Anaphylaxis; Desensitization, Immunologic; Diagnosis, Differential; Diphenhydramine; Epinephrine; Ho | 1993 |
2 trials available for diphenhydramine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.
Topics: Administration, Oral; Adolescent; Adult; Child; Cross-Over Studies; Diphenhydramine; Double-Blind Me | 2008 |
Seasonal allergic rhinitis and antihistamine effects on children's learning.
Topics: Child; Cognition; Diphenhydramine; Female; Humans; Hypersensitivity, Immediate; Learning; Loratadine | 1993 |
23 other studies available for diphenhydramine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Immediate hypersensitivity reaction following liposomal amphotericin-B (AmBisome) infusion.
Topics: Adult; Amphotericin B; Bangladesh; Child; Diphenhydramine; Emergencies; Epinephrine; Female; Humans; | 2014 |
Cross-reactivity between paclitaxel and hazelnut: a case report.
Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Corylus; Cross Reactions; Diphenh | 2007 |
The activity of a new, novel inhibitor of leukotriene synthesis in rhesus monkey Ascaris reactors.
Topics: Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Diphenhydramine; Dose-Response Relationship | 1983 |
The biologic activity of mast cell granules. V. The effects of antihistamine treatment on rat cutaneous early- and late-phase allergic reactions.
Topics: Animals; Antibodies, Anti-Idiotypic; Ascitic Fluid; Capillary Permeability; Cimetidine; Cytoplasmic | 1983 |
Allergic reactions to dental materials, drugs require an alert response from practitioner.
Topics: Adolescent; Anesthetics, Local; Anti-Bacterial Agents; Contraindications; Dental Materials; Dermatit | 1997 |
Characterization of antihistamines using biphasic cutaneous reaction in BALB/c mice.
Topics: Animals; Cyproheptadine; Dermatitis, Allergic Contact; Diphenhydramine; Dose-Response Relationship, | 1998 |
Allergic reaction associated with intravenous marijuana use.
Topics: Adult; Cannabis; Diphenhydramine; Drug Therapy, Combination; Emergency Service, Hospital; Epinephrin | 2000 |
Management of the latex hypersensitive patient in the endodontic office.
Topics: Adult; Dental Care for Chronically Ill; Diphenhydramine; Female; Gutta-Percha; Humans; Hypersensitiv | 1999 |
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes.
Topics: Airway Resistance; Animals; Antigens; Bile; Chromones; Complement C5a; Complement C5a, des-Arginine; | 2000 |
Macular rash following influenza vaccine.
Topics: Anti-Allergic Agents; Diphenhydramine; Erythema; Humans; Hypersensitivity, Immediate; Influenza Vacc | 2000 |
An urticarial IgE-mediated reaction to interferon beta-1b.
Topics: Adult; Anti-Allergic Agents; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Hypersensitivit | 2001 |
Effect of beta adrenergic stimulation and blockade on cutaneous reactivity to histamine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Diphenhydramine; Histamine; Humans; Hy | 1976 |
Prednisone-diphenhydramine regimen prior to use of radiographic contrast media.
Topics: Diphenhydramine; Humans; Hypersensitivity, Immediate; Prednisone | 1979 |
[Acute epidermal necrolysis (Lyell's syndrome) after diagnostic curettage of the uterus].
Topics: Acute Disease; Aged; Dilatation and Curettage; Diphenhydramine; Drug Hypersensitivity; Female; Human | 1978 |
Contact urticaria syndrome. Contact urticaria to diethyltoluamide (immediate-type hypersensitivity).
Topics: Adult; Ammonium Sulfate; Atropine; Benzamides; Benzocaine; Chlorpheniramine; DEET; Dermatitis, Conta | 1975 |
Systematic approach to diagnosis and management of biphasic insulin allergy with local anti-inflammatory agents.
Topics: Aged; Diabetes Mellitus; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Hydrocortisone; Hyp | 1989 |
Significant envenomation from a preserved rattlesnake head (in a patient with a history of immediate hypersensitivity to antivenin).
Topics: Administration, Oral; Adult; Animals; Antivenins; Crotalid Venoms; Diphenhydramine; Epinephrine; Hum | 1986 |
Cardiac arrhythmia following a hornet sting.
Topics: Adult; Cardiac Complexes, Premature; Creatine Kinase; Diphenhydramine; Humans; Hypersensitivity, Del | 1970 |
Immunoglobulin E-mediated respiratory responses of subhuman primates. Reproducibility and effect of certain pharmacologic agents.
Topics: Aerosols; Animals; Antigens; Ascaris; Diphenhydramine; Female; gamma-Globulins; Haplorhini; Histamin | 1970 |
A rare allergic reaction to sodium methohexital.
Topics: Adult; Anesthesia, Dental; Angioedema; Diphenhydramine; Humans; Hypersensitivity, Immediate; Male; M | 1972 |
Effect of beta adrenergic stimulation and blockade on immediate hypersensitivity skin test reactions.
Topics: Asthma; Diphenhydramine; Humans; Hypersensitivity, Immediate; Iontophoresis; Isoproterenol; Proprano | 1973 |
Systemic reactions to stinging ants.
Topics: Adolescent; Adult; Ants; Bees; Child; Child, Preschool; Desensitization, Immunologic; Diphenhydramin | 1974 |
Sensitization to duck-embryo rabies vaccine produced by prior yellow-fever vaccination.
Topics: Adult; Animals; Diphenhydramine; Embryo, Mammalian; Embryo, Nonmammalian; Female; Humans; Hypersensi | 1966 |