diphenhydramine has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 4 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control." | 3.66 | Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy. ( Robertson, D; Stacpoole, PW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moulin, DE | 1 |
| Morley-Forster, PK | 1 |
| Pirani, Z | 1 |
| Rohfritsch, C | 1 |
| Stitt, L | 1 |
| Shimizu, T | 1 |
| Tokuda, Y | 1 |
| Stacpoole, PW | 1 |
| Robertson, D | 1 |
| Yoshikawa, H | 1 |
| Kawai, K | 1 |
| Inoue, S | 1 |
| Murayama, Y | 1 |
| Kuzuya, N | 1 |
| Fujita, T | 1 |
| Koide, Y | 1 |
| Yamashita, K | 1 |
| Yoshizawa, K | 1 |
| Mizusawa, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin[NCT01669967] | 34 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for diphenhydramine and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Intravenous lidocaine in the management of chronic peripheral neuropathic pain: a randomized-controlled trial.
Topics: Aged; Anesthetics, Local; Chronic Pain; Cross-Over Studies; Diabetic Neuropathies; Diphenhydramine; | 2019 |
3 other studies available for diphenhydramine and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Acute urinary retention.
Topics: Acute Disease; Aged; Cholinergic Antagonists; Diabetic Neuropathies; Diphenhydramine; Female; Humans | 2011 |
Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy.
Topics: Adult; Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Drug Therapy, Combination; Hist | 1982 |
[A case of diabetic orthostatic hypotension effectively managed with L-dops (L-threo-3,4-dihydroxyphenylserine)].
Topics: Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Droxidopa; Humans; Hypotension, Orthos | 1987 |