diphenhydramine has been researched along with Alloxan Diabetes in 4 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 7.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 3.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| "Pretreatment with diphenhydramine (5 x 10(-7)) on aortic rings from 12 and 52-week age matched rats resulted in qualitatively similar histamine dose-response curves that were displaced about two orders of magnitude to the right, indicative of H1 receptor competitive antagonism." | 1.28 | Histamine relaxation of aortic rings from diabetic rats. ( Chang, KS; Tanz, RD; Weller, TS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishiwata, Y | 1 |
| Yasuhara, M | 1 |
| Nagai, K | 1 |
| Niijima, A | 1 |
| Yamano, T | 1 |
| Otani, H | 1 |
| Okumra, N | 1 |
| Tsuruoka, N | 1 |
| Nakai, M | 1 |
| Kiso, Y | 1 |
| Hiai, S | 1 |
| Yokoyama, H | 1 |
| Oura, H | 1 |
| Tanz, RD | 1 |
| Chang, KS | 1 |
| Weller, TS | 1 |
4 other studies available for diphenhydramine and Alloxan Diabetes
| Article | Year |
|---|---|
Gatifloxacin-induced histamine release and hyperglycemia in rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Blood Glucose; Diabetes Mellitus, Experimental | 2010 |
Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves.
Topics: Animals; Autonomic Pathways; Blood Glucose; Carnosine; Deoxyglucose; Diabetes Mellitus, Experimental | 2003 |
Features of ginseng saponin-induced corticosterone secretion.
Topics: Animals; Blood Glucose; Body Temperature; Corticosterone; Diabetes Mellitus, Experimental; Diphenhyd | 1979 |
Histamine relaxation of aortic rings from diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diphenhydramine; Endothelium, Vascular; H | 1989 |