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diphenhydramine and Aging

diphenhydramine has been researched along with Aging in 5 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"To evaluate attention deficit in Alzheimer's disease (AD) and its relationship to attention deficits associated with aging and with medications altering alertness."1.29Attention deficit in Alzheimer's disease is not simulated by an anticholinergic/antihistaminergic drug and is distinct from deficits in healthy aging. ( Howieson, DB; Kaye, JA; Kishiyama, SS; Oken, BS, 1994)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koyanagi, T1
Yamaura, Y1
Yano, K1
Kim, S1
Yamazaki, H1
Douglas, JS1
Duncan, PG1
Mukhopadhyay, A1
Oken, BS1
Kishiyama, SS1
Kaye, JA1
Howieson, DB1
Onodera, S1
Yoshinaga, M1
Takenaga, K1
Toyoshima, A1
Uchiyama, T1
Maggi, CA1
Giuliani, S1
Santicioli, P1
Abelli, L1
Regoli, D1
Meli, A1

Other Studies

5 other studies available for diphenhydramine and Aging

ArticleYear
Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs.
    Xenobiotica; the fate of foreign compounds in biological systems, 2014, Volume: 44, Issue:10

    Topics: Acetaminophen; Age Factors; Aging; Albumins; Animals; Antipyrine; Blood Proteins; Diazepam; Diphenhy

2014
The antagonism of histamine-induced tracheal and bronchial muscle contraction by diphenhydramine: effect of maturation.
    British journal of pharmacology, 1984, Volume: 83, Issue:3

    Topics: Aging; Animals; Bronchi; Carbachol; Diphenhydramine; Guinea Pigs; Histamine; Histamine Antagonists;

1984
Attention deficit in Alzheimer's disease is not simulated by an anticholinergic/antihistaminergic drug and is distinct from deficits in healthy aging.
    Neurology, 1994, Volume: 44, Issue:4

    Topics: Aged; Aging; Alzheimer Disease; Analysis of Variance; Attention; Diphenhydramine; Female; Histamine

1994
[Effects of cernitin pollen extract (CN-009) on the isolated bladder smooth muscles and the intravesical pressure].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:5

    Topics: Aging; Animals; Atropine; Cats; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Drug

1991
Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: evidence for the involvement of the capsaicin-sensitive bladder mechanoreceptors.
    European journal of pharmacology, 1987, Apr-14, Volume: 136, Issue:2

    Topics: Aging; Animals; Capsaicin; Diphenhydramine; Electric Stimulation; In Vitro Techniques; Indomethacin;

1987