diphenhydramine has been researched along with Acute Lymphoid Leukemia in 4 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This report describes an unexpected adverse effect in three children receiving teniposide at 3-5 times the conventional dosage (i." | 1.28 | Somnolence, hypotension, and metabolic acidosis following high-dose teniposide treatment in children with leukemia. ( Baker, DK; McLeod, HL; Pui, CH; Rodman, JH, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MacGinnitie, AJ | 1 |
| Walensky, LD | 1 |
| Turvey, SE | 1 |
| Orange, JS | 1 |
| Bonilla, FA | 1 |
| Silverman, LB | 1 |
| Oettgen, H | 1 |
| Malaviya, R | 1 |
| Uckun, FM | 1 |
| McLeod, HL | 1 |
| Baker, DK | 1 |
| Pui, CH | 2 |
| Rodman, JH | 2 |
| Kellie, SJ | 1 |
| Crist, WM | 1 |
| Crone, ME | 1 |
| Fairclough, DL | 1 |
| Rivera, GK | 1 |
4 other studies available for diphenhydramine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.
Topics: Adolescent; Anaphylaxis; Anti-Allergic Agents; Antimetabolites, Antineoplastic; Antipruritics; Diphe | 2003 |
Histamine as an autocrine regulator of leukemic cell proliferation.
Topics: Adolescent; Autocrine Communication; Cell Division; Child; Child, Preschool; Diphenhydramine; Female | 2000 |
Somnolence, hypotension, and metabolic acidosis following high-dose teniposide treatment in children with leukemia.
Topics: Acidosis; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Diphe | 1991 |
Hypersensitivity reactions to epipodophyllotoxins in children with acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Bronchial Spasm | 1991 |