diphenhydramine has been researched along with Acute Kidney Injury in 6 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of a suicide attempt in a young adult male where ingestion of the antihistamines diphenhydramine and doxylamine was complicated by non-traumatic rhabdomyolysis and acute renal failure." | 3.68 | Non-traumatic rhabdomyolysis complicating antihistamine overdose. ( Dolgin, J; Frankel, D; Murray, BM, 1993) |
| " Here, based on a repositioning analysis of the Food and Drug Administration Adverse Events Reporting System, we found that a previously developed drug, diphenhydramine, may provide a novel treatment for cisplatin-induced kidney toxicity." | 1.62 | Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity. ( Aihara, KI; Chuma, M; Fujino, H; Fukushima, K; Goda, M; Hamano, H; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kishi, S; Miyamoto, L; Niimura, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yamashita, M; Zamami, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hamano, H | 1 |
| Ikeda, Y | 1 |
| Goda, M | 1 |
| Fukushima, K | 1 |
| Kishi, S | 1 |
| Chuma, M | 1 |
| Yamashita, M | 1 |
| Niimura, T | 1 |
| Takechi, K | 1 |
| Imanishi, M | 1 |
| Zamami, Y | 1 |
| Horinouchi, Y | 1 |
| Izawa-Ishizawa, Y | 1 |
| Miyamoto, L | 1 |
| Ishizawa, K | 1 |
| Fujino, H | 1 |
| Tamaki, T | 1 |
| Aihara, KI | 1 |
| Tsuchiya, K | 1 |
| Gupta, S | 1 |
| Leaf, DE | 1 |
| Mycyk, MB | 1 |
| Mazor, SS | 1 |
| Hampel, G | 1 |
| Horstkotte, H | 1 |
| Rumpf, KW | 1 |
| Frankel, D | 1 |
| Dolgin, J | 1 |
| Murray, BM | 1 |
| Steinhoff, J | 1 |
| Kirschstein, M | 1 |
| Castan, H | 1 |
| Sack, K | 1 |
6 other studies available for diphenhydramine and Acute Kidney Injury
| Article | Year |
|---|---|
Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Diphenhydramine; Humans; | 2021 |
Diphenhydramine for the prevention of cisplatin-associated acute kidney injury.
Topics: Acute Kidney Injury; Cisplatin; Diphenhydramine; Humans; Kidney; Vomiting | 2021 |
Comment: Rhabdomyolysis and acute renal failure following an ethanol and diphenhydramine overdose.
Topics: Acute Kidney Injury; Adult; Diphenhydramine; Drug Overdose; Ethanol; Humans; Male; Rhabdomyolysis; T | 2003 |
Myoglobinuric renal failure due to drug-induced rhabdomyolysis.
Topics: Acute Kidney Injury; Adult; Creatine Kinase; Creatinine; Diphenhydramine; Humans; Male; Muscular Dis | 1983 |
Non-traumatic rhabdomyolysis complicating antihistamine overdose.
Topics: Acute Kidney Injury; Adult; Blood Urea Nitrogen; Creatinine; Diphenhydramine; Doxylamine; Drug Overd | 1993 |
[Acute oliguric kidney failure after rhabdomyolysis caused by diphenhydramine].
Topics: Acute Kidney Injury; Adult; Diphenhydramine; Humans; Male; Oliguria; Rhabdomyolysis; Suicide, Attemp | 1985 |