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diphenhydramine and Acute Hemolytic Transfusion Reaction

diphenhydramine has been researched along with Acute Hemolytic Transfusion Reaction in 8 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research Excerpts

ExcerptRelevanceReference
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."9.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."5.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duran, J1
Siddique, S1
Cleary, M1
Kennedy, LD1
Case, LD1
Hurd, DD1
Cruz, JM1
Pomper, GJ1
Tobian, AA1
King, KE1
Ness, PM1
Martí-Carvajal, AJ1
Solà, I1
González, LE1
Leon de Gonzalez, G1
Rodriguez-Malagon, N1
FLIEGEL, W1
Wang, JS1
Sackett, DJ1
Yuan, YM1
Huggins, RA1
Smith, EL1
Deavers, S1
Mason, DY1
Ingram, GI1

Reviews

2 reviews available for diphenhydramine and Acute Hemolytic Transfusion Reaction

ArticleYear
Effects of Leukoreduction and Premedication With Acetaminophen and Diphenhydramine in Minimizing Febrile Nonhemolytic Transfusion Reactions and Allergic Transfusion Reactions During and After Blood Product Administration: A Literature Review With Recommen
    Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses, 2014, Volume: 31, Issue:4

    Topics: Acetaminophen; Diphenhydramine; Drug Administration Schedule; Erythrocyte Transfusion; Evidence-Base

2014
Pharmacological interventions for the prevention of allergic and febrile non-haemolytic transfusion reactions.
    The Cochrane database of systematic reviews, 2010, Jun-16, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Fever; Histamine H1 Antagon

2010

Trials

2 trials available for diphenhydramine and Acute Hemolytic Transfusion Reaction

ArticleYear
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Do

2008
[Randomized clinical controlled cross-over trial (RCT) in the prevention of blood transfusion febrile reactions with small dose hydrocortisone versus anti-histamines].
    Zhonghua nei ke za zhi, 1992, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Aged; Diphenhydramine; Female; Fever; Humans; Hydrocortisone; Male; Middle Aged;

1992

Other Studies

4 other studies available for diphenhydramine and Acute Hemolytic Transfusion Reaction

ArticleYear
Prevention of febrile nonhemolytic and allergic transfusion reactions with pretransfusion medication: is this evidence-based medicine?
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Anemia, Hemolytic; Diphenhydramine; Evidence-Based Medicine; Fever; Humans; Leukocyte

2008
[Effects of the antihistaminic systral in blood transfusions].
    Medizinische Klinik, 1959, Mar-20, Volume: 54, Issue:12

    Topics: Blood Transfusion; Diphenhydramine; Ethylamines; Humans; Transfusion Reaction

1959
Some effects of autologous and homologous blood or plasma overtransfusions in the dog.
    The American journal of physiology, 1965, Volume: 209, Issue:4

    Topics: Animals; Blood Proteins; Blood Volume; Dextrans; Diphenhydramine; Dogs; Histamine Release; Transfusi

1965
Management of the hereditary coagulation disorders.
    Seminars in hematology, 1971, Volume: 8, Issue:2

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; Cerebral Hemorrhage

1971