diphenhydramine has been researched along with Abnormalities, Drug-Induced in 6 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
Excerpt | Relevance | Reference |
---|---|---|
"Ingestion of the anticonvulsant drug valproic acid and of the angiotensin converting enzyme inhibitor captopril during pregnancy has been associated with abnormal fetal outcome in humans." | 3.69 | Evaluation of the rat embryo culture system as a predictive test for human teratogens. ( Buttar, HS; Guest, I; Smith, S; Varma, DR, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (83.33) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
WINBERG, J | 1 |
Guest, I | 1 |
Buttar, HS | 1 |
Smith, S | 1 |
Varma, DR | 1 |
Fraile, A | 1 |
Alía, M | 1 |
Herranz, JM | 1 |
Naranjo, P | 1 |
de Naranjo, E | 1 |
Iuliucci, JD | 1 |
Gautieri, RF | 1 |
Schardein, JL | 1 |
Hentz, DL | 1 |
Petrere, JA | 1 |
Kurtz, SM | 1 |
6 other studies available for diphenhydramine and Abnormalities, Drug-Induced
Article | Year |
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[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di | 1964 |
Evaluation of the rat embryo culture system as a predictive test for human teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Captopril; Diphenhydramine; DNA; Embryo, Mammalian; False Nega | 1994 |
[Study on the teratogenicity of benadryl in rats (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Diphenhydramine; Female; Fetal Death; Pregnancy; Rats | 1977 |
Embryotoxic effects of antihistamines.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Chlorpheniramine; Diphenhy | 1968 |
Morphine-induced fetal malformations. II. Influence of histamine and diphenhydramine.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cryptorchidism; Diphenhydramine; Drug Synergis | 1971 |
Teratogenesis studies with diphenhydramine HCl.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Corpus Luteum; Diphenh | 1971 |