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diphenhydramine and Abnormalities, Drug-Induced

diphenhydramine has been researched along with Abnormalities, Drug-Induced in 6 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Ingestion of the anticonvulsant drug valproic acid and of the angiotensin converting enzyme inhibitor captopril during pregnancy has been associated with abnormal fetal outcome in humans."3.69Evaluation of the rat embryo culture system as a predictive test for human teratogens. ( Buttar, HS; Guest, I; Smith, S; Varma, DR, 1994)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WINBERG, J1
Guest, I1
Buttar, HS1
Smith, S1
Varma, DR1
Fraile, A1
Alía, M1
Herranz, JM1
Naranjo, P1
de Naranjo, E1
Iuliucci, JD1
Gautieri, RF1
Schardein, JL1
Hentz, DL1
Petrere, JA1
Kurtz, SM1

Other Studies

6 other studies available for diphenhydramine and Abnormalities, Drug-Induced

ArticleYear
[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
    Svenska lakartidningen, 1964, Mar-18, Volume: 61

    Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di

1964
Evaluation of the rat embryo culture system as a predictive test for human teratogens.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Captopril; Diphenhydramine; DNA; Embryo, Mammalian; False Nega

1994
[Study on the teratogenicity of benadryl in rats (author's transl)].
    Archivos de farmacologia y toxicologia, 1977, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Diphenhydramine; Female; Fetal Death; Pregnancy; Rats

1977
Embryotoxic effects of antihistamines.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Chlorpheniramine; Diphenhy

1968
Morphine-induced fetal malformations. II. Influence of histamine and diphenhydramine.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cryptorchidism; Diphenhydramine; Drug Synergis

1971
Teratogenesis studies with diphenhydramine HCl.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:4

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Corpus Luteum; Diphenh

1971