Compounds > diosgenin
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diosgenin and Prostatic Neoplasms

diosgenin has been researched along with Prostatic Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Hu, H; Li, XL; Liu, HH; Liu, JG; Ran, YH; Ren, QL; Song, ZX; Tang, JJ; Wang, M; Wang, Q; Yang, XT; Zhang, XQ1
Cao, G; Jiang, Y; Kong, F; Li, K; Lin, Z; Liu, S; Liu, Z; Ma, C; Sun, C; Wang, P; Xu, D; Zhang, D; Zhang, J; Zhao, S1
Ahn, KS; Alahmadi, TA; Alharbi, SA; Chinnathambi, A; Hui, KM; Kumar, AP; Lee, JH; Ong, TH; Rajendran, P; Sethi, G; Shanmugam, MK; Sikka, S; Siveen, KS; Vali, S; Wang, L; Yang, MH1
Deng, J; Feng, T; Liu, J; Liu, X; Liu, Y; Ma, K; Si, Y; Sun, Z; Tan, Y; Zhang, T1
Chen, J; Li, HM; Ruan, JL; Xiong, CM; Zhang, XN1
Liu, J; Nie, C; Qin, X; Shi, X; Yan, S; Zeng, Q; Zhang, L; Zhou, J1
Anchoori, RK; Carducci, MA; Davidson, N; Hidalgo, M; Jimeno, A; Kachhap, S; Khan, SR; Shabbeer, S; Sobolewski, M1
Chang, HY; Fu, E; Ho, CT; Kao, MC; Way, TD1
Chen, PS; Cheng, HW; Huang, HC; Shih, YW1
Bhardwaj, TR; Dhingra, N; Kumar, A; Kumar, M; Mehta, N; Mukhopadhyay, T1
Chai, H; Cordell, GA; Farnsworth, NR; Hollingshead, MG; Kardono, LB; Kinghorn, AD; Lantvit, D; Lee, IS; Mayo, JG; Mi, Q; Ngassapa, O; Peraza-Sánchez, S; Pezzuto, JM; Reyes-Lim, E; Riswan, S; Zhao, W1

Reviews

1 review(s) available for diosgenin and Prostatic Neoplasms

ArticleYear
Anticancer Activity of Diosgenin and Its Molecular Mechanism.
    Chinese journal of integrative medicine, 2023, Volume: 29, Issue:8

    Topics: Apoptosis; Carcinoma, Squamous Cell; Diosgenin; Humans; Male; Mouth Neoplasms; Prostatic Neoplasms

2023

Other Studies

10 other study(ies) available for diosgenin and Prostatic Neoplasms

ArticleYear
Polyphyllin I induces cell cycle arrest in prostate cancer cells via the upregulation of IL6 and P21 expression.
    Medicine, 2019, Volume: 98, Issue:44

    Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diosgenin; Humans; Interleukin-6; Male; Prostatic Neoplasms; Up-Regulation

2019
Diosgenin attenuates tumor growth and metastasis in transgenic prostate cancer mouse model by negatively regulating both NF-κB/STAT3 signaling cascades.
    European journal of pharmacology, 2021, Sep-05, Volume: 906

    Topics: Administration, Oral; Animals; Cell Line, Tumor; Computer Simulation; Diosgenin; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Transgenic; NF-kappa B; Prostatic Neoplasms; Proteomics; Signal Transduction; STAT3 Transcription Factor

2021
Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer.
    International journal of oncology, 2018, Volume: 53, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoantigens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diosgenin; Down-Regulation; Drug Evaluation, Preclinical; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Humans; Intracellular Signaling Peptides and Proteins; Male; Melanthiaceae; Membrane Proteins; Mice; Mice, Nude; Neoplasm Invasiveness; Phosphorylation; Prostatic Neoplasms; Protein Phosphatase 2; Signal Transduction; Xenograft Model Antitumor Assays

2018
Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein family.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2014, Volume: 34, Issue:1

    Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Humans; Male; Molecular Structure; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Time Factors

2014
Diosgenin‑induced autophagy and apoptosis in a human prostate cancer cell line.
    Molecular medicine reports, 2016, Volume: 14, Issue:5

    Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Diosgenin; Gene Expression Regulation, Neoplastic; Humans; Male; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Signal Transduction; TOR Serine-Threonine Kinases

2016
Fenugreek: a naturally occurring edible spice as an anticancer agent.
    Cancer biology & therapy, 2009, Volume: 8, Issue:3

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Diosgenin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Male; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Signal Transduction; Spices; Sulfoxides; Thiocyanates; Trigonella

2009
Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin.
    Journal of agricultural and food chemistry, 2011, May-25, Volume: 59, Issue:10

    Topics: Diosgenin; Epithelium; Hepatocyte Growth Factor; Humans; Male; Mesoderm; Neoplasm Invasiveness; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; TOR Serine-Threonine Kinases; Vimentin

2011
Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Basigin; Cell Line, Tumor; Cell Movement; Diosgenin; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; NF-kappa B; Phosphatidylinositol 3-Kinase; Polymerase Chain Reaction; Prostatic Neoplasms; Tissue Inhibitor of Metalloproteinase-2; Vascular Endothelial Growth Factor A

2011
Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives.
    Archives of pharmacal research, 2011, Volume: 34, Issue:7

    Topics: Androgen Antagonists; Androgens; Androstanes; Androstenes; Androstenols; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Finasteride; Humans; Inhibitory Concentration 50; Lethal Dose 50; Macrophages; Male; Mice; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2011
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
    Journal of natural products, 2002, Volume: 65, Issue:6

    Topics: Animals; Biological Factors; Colonic Neoplasms; Diosgenin; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 3-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; KB Cells; Leukemia P388; Male; Melanoma; Mice; Molecular Structure; Naphthoquinones; Ovarian Neoplasms; Paclitaxel; Polymers; Prostatic Neoplasms; Triterpenes; Tumor Cells, Cultured

2002