Page last updated: 2024-08-26

diosgenin and Osteosarcoma

diosgenin has been researched along with Osteosarcoma in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Cai, X; Chen, L; Cheng, C; Ding, Q; Liu, X; Mo, F; Peng, G; Wang, J; Yang, S; Zhang, W1
Chang, J; Hu, S; Li, Y; Shi, Q; Wang, H; Wang, X; Wang, Y; Yang, Y1
Jia, Q; Li, W; Liu, W; Shen, J; Su, Q; Wang, Y; Yin, J; Zhang, J; Zhang, X; Zhao, Z1
Chen, J; Duan, H; Fang, X; Hou, D; Jiang, T; Liu, P; Long, C; Zhou, H1
Chang, J; Li, Y; Lu, S; Shi, Q; Wang, C; Wang, H; Wang, X; Wang, Y; Yang, Y; Yang, Z; Zeng, Q; Zhao, D; Zhao, Y; Zimmerman, J1
Chang, IL; Chen, CL; Chen, HY; Cheng, CH; Hsieh, CP; Shen, TS; Tseng, SC; Wu, CC1
Beneytout, JL; Bianchi, A; Bordji, K; Corbiere, C; Dauça, M; Liagre, B; Netter, P1
Battu, S; Beneytout, JL; Cardot, PJ; Corbière, C; Liagre, B1
Beneytout, JL; Corbière, C; Duroux, JL; Liagre, B; Trouillas, P1
Beneytout, JL; Bianchi, A; Bordji, K; Corbière, C; Dauça, M; Liagre, B; Moalic, S1

Other Studies

10 other study(ies) available for diosgenin and Osteosarcoma

ArticleYear
Dioscin inhibits the growth of human osteosarcoma by inducing G2/M-phase arrest, apoptosis, and GSDME-dependent cell death in vitro and in vivo.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Apoptosis; Bone Neoplasms; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Diosgenin; G2 Phase Cell Cycle Checkpoints; Humans; Osteosarcoma; Pyroptosis; Receptors, Estrogen

2020
Polyphyllin I suppresses human osteosarcoma growth by inactivation of Wnt/β-catenin pathway in vitro and in vivo.
    Scientific reports, 2017, 08-08, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Diosgenin; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mice, Nude; Osteosarcoma; Protein Kinase Inhibitors; Pyridines; Pyrimidines; RNA, Small Interfering; Signal Transduction; Wnt Proteins; Xenograft Model Antitumor Assays

2017
Dioscin inhibits stem-cell-like properties and tumor growth of osteosarcoma through Akt/GSK3/β-catenin signaling pathway.
    Cell death & disease, 2018, 03-01, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents; beta Catenin; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Child; Diosgenin; Female; Glycogen Synthase Kinase 3; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplastic Stem Cells; Osteosarcoma; Proto-Oncogene Proteins c-akt; Signal Transduction; Young Adult

2018
Diosgenin exerts its tumor suppressive function via inhibition of Cdc20 in osteosarcoma cells.
    Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cdc20 Proteins; Cell Line, Tumor; Cell Movement; Diosgenin; Humans; Neoplasm Invasiveness; Osteosarcoma

2019
Molecular mechanisms of Polyphyllin I-induced apoptosis and reversal of the epithelial-mesenchymal transition in human osteosarcoma cells.
    Journal of ethnopharmacology, 2015, Jul-21, Volume: 170

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Bone Neoplasms; Cell Line, Tumor; Diosgenin; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Liliaceae; Molecular Targeted Therapy; Osteosarcoma; Proteasome Endopeptidase Complex; Up-Regulation

2015
Methyl Protodioscin Induces Apoptosis in Human Osteosarcoma Cells by Caspase-Dependent and MAPK Signaling Pathways.
    Journal of agricultural and food chemistry, 2017, Apr-05, Volume: 65, Issue:13

    Topics: Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Caspase 3; Caspase 9; Cell Line, Tumor; Dioscorea; Diosgenin; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Osteosarcoma; Phosphorylation; Plant Extracts; Saponins

2017
Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells.
    International journal of oncology, 2003, Volume: 22, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diosgenin; Drugs, Chinese Herbal; Electrophoresis, Polyacrylamide Gel; Humans; Luciferases; Microscopy, Fluorescence; Models, Chemical; Osteosarcoma; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Sapogenins; Spirostans; Time Factors; Transcription Factors; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53

2003
SdFFF monitoring of cellular apoptosis induction by diosgenin and different inducers in the human 1547 osteosarcoma cell line.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Sep-05, Volume: 808, Issue:2

    Topics: Apoptosis; Bone Neoplasms; Cell Line, Tumor; Diosgenin; Humans; Osteosarcoma

2004
Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin.
    Bioorganic & medicinal chemistry, 2005, Feb-15, Volume: 13, Issue:4

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Diosgenin; Humans; Models, Molecular; Osteosarcoma; Saponins; Structure-Activity Relationship

2005
A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells.
    FEBS letters, 2001, Oct-12, Volume: 506, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diosgenin; Enzyme Induction; G1 Phase; Humans; L-Lactate Dehydrogenase; NF-kappa B; Osteosarcoma; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001