Page last updated: 2024-08-26

diosgenin and Neoplasms

diosgenin has been researched along with Neoplasms in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (26.92)29.6817
2010's12 (46.15)24.3611
2020's7 (26.92)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1
Liu, Y; Xu, Z; Zhao, SJ1
Anand, U; Bandopadhyay, S; Behl, T; Dey, A; Gadekar, VS; Gupta, PK; Jha, NK; Kumar, M; Shekhawat, MS1
Dharani, S; Kalaiarasi, G; Lynch, VM; Prabhakaran, R; Ravi, M; Sathan Raj, N1
Abu-Izneid, T; Alshehri, MM; Calina, D; Cho, WC; Das, R; Daştan, SD; Emran, TB; Kumar, M; Mitra, S; Painuli, S; Rauf, A; Semwal, P; Sharifi-Rad, J; Sharma, A; Taheri, Y1
Fang, MY; Gong, GY; Ma, LL; Song, D; Tian, Y; Wang, ZQ1
Jiang, W; Lin, M; Wang, Z1
Ahn, KS; Arya, A; Banik, K; Boruah, M; Dutta, U; Harsha, C; Kunnumakkara, AB; Mao, X; Parama, D; Rana, V; Thakur, KK; Yachna, K1
Bhardwaj, N; Goel, B; Jain, SK; Tripathi, N1
Akhtar, N; Hameed, A; Ijaz, S; Khan, HMS; Mohammad, IS; Muhammad, KS1
Peng, J; Qi, Y; Tao, X; Xu, L; Yin, L; Zhao, L1
Arfuso, F; Bishayee, A; Kumar, AP; Merarchi, M; Sethi, G; Shanmugam, MK; Warrier, S1
Peng, J; Tao, X; Xu, L; Yin, L1
Bitó, T; Frank, E; Minorics, R; Molnár, J; Ocsovszki, I; Puskás, LG; Réthy, B; Topcu, Z; Wölfling, J; Zupkó, I1
Chen, MW; Cheng, KJ; Jiang, QW; Shi, Z; Wei, X; Yu, PZ1
Dong, D; Han, X; Peng, J; Qi, Y; Xu, L; Xu, Y; Yin, L; Zhao, Y; Zheng, L1
Battu, S; Bégaud-Grimaud, G; Beneytout, JL; Bertrand, J; Cardot, P; Jauberteau, MO; Liagre, B1
Mehta, R; Raju, J1
Anchoori, RK; Carducci, MA; Davidson, N; Hidalgo, M; Jimeno, A; Kachhap, S; Khan, SR; Shabbeer, S; Sobolewski, M1
Mandal, M; Rajput, S1
Chen, C; Chen, T; He, J; Liu, X; Wen, F; Xue, D; Yin, H; Zhang, H1
Delemasure, S; Duchamp, O; Dutartre, P; Lacaille-Dubois, MA; Manase, MJ; Mirjolet, JF; Mitaine-Offer, AC; Miyamoto, T; Pertuit, D; Tanaka, C1
Beneytout, JL; Cook-Moreau, J; Corbière, C; Leger, DY; Liagre, B1
He, X; Jiang, M; Liu, B; Qiao, A; Su, L; Wang, X; Yao, X1
Hu, K; Yao, X1

Reviews

14 review(s) available for diosgenin and Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles

2019
Dioscin: A review on pharmacological properties and therapeutic values.
    BioFactors (Oxford, England), 2022, Volume: 48, Issue:1

    Topics: Diosgenin; Humans; Neoplasms; Plant Extracts; Saponins

2022
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Asthma; Diosgenin; Humans; Neoplasms; Phytochemicals; Plant Extracts; Trigonella

2022
Anti-cancer effects of Polyphyllin I: An update in 5 years.
    Chemico-biological interactions, 2020, Jan-25, Volume: 316

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Diosgenin; Drug Resistance, Neoplasm; Humans; Medicine, Chinese Traditional; Neoplasms

2020
Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases.
    Life sciences, 2020, Nov-01, Volume: 260

    Topics: Animals; Biological Availability; Cardiovascular Diseases; Chemical Phenomena; Chronic Disease; Diosgenin; Humans; Inflammation; Neoplasms; Nervous System Diseases; Phytotherapy; PubMed; Seeds; Signal Transduction; Trigonella

2020
Anticancer Activity of Diosgenin and Its Semi-synthetic Derivatives: Role in Autophagy Mediated Cell Death and Induction of Apoptosis.
    Mini reviews in medicinal chemistry, 2021, Volume: 21, Issue:13

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Diosgenin; Humans; Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2021
Aglycone solanidine and solasodine derivatives: A natural approach towards cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Diosgenin; Humans; Models, Biological; Neoplasms; Solanaceous Alkaloids

2017
Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review.
    Nutrients, 2018, 05-19, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Diosgenin; Humans; Neoplasms; Signal Transduction

2018
Dioscin: A diverse acting natural compound with therapeutic potential in metabolic diseases, cancer, inflammation and infections.
    Pharmacological research, 2018, Volume: 137

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Diosgenin; Humans; Metabolic Diseases; Neoplasms

2018
Therapeutic Potential of Steroidal Alkaloids in Cancer and Other Diseases.
    Medicinal research reviews, 2016, Volume: 36, Issue:1

    Topics: Alkaloids; Androgens; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Diosgenin; Estrogens; Humans; Mice; Neoplasms; Solanaceous Alkaloids; Steroids; Tomatine; Veratrum Alkaloids

2016
Cancer chemopreventive and therapeutic effects of diosgenin, a food saponin.
    Nutrition and cancer, 2009, Volume: 61, Issue:1

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Cell Division; Diosgenin; Humans; Neoplasms; Saponins

2009
Antitumor promoting potential of selected phytochemicals derived from spices: a review.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2012, Volume: 21, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Capsaicin; Diosgenin; Humans; Models, Biological; Neoplasms; Plant Extracts; Signal Transduction; Spices

2012

Other Studies

12 other study(ies) available for diosgenin and Neoplasms

ArticleYear
Diosgenin derivatives developed from Pd(II) catalysed dehydrogenative coupling exert an effect on breast cancer cells by abrogating their growth and facilitating apoptosis
    Dalton transactions (Cambridge, England : 2003), 2022, May-03, Volume: 51, Issue:17

    Topics: Amination; Apoptosis; Catalysis; Diosgenin; Neoplasms; Signal Transduction

2022
Dioscin: A new potential inhibitor of Skp2 for cancer therapy.
    EBioMedicine, 2020, Volume: 51

    Topics: Animals; Biological Products; Cell Line, Tumor; Diosgenin; Humans; Mice; Neoplasms; S-Phase Kinase-Associated Proteins; Xenograft Model Antitumor Assays

2020
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
    Redox biology, 2018, Volume: 16

    Topics: Animals; Apoptosis; Cardiotoxicity; Cell Survival; Diosgenin; Doxorubicin; Gene Expression Regulation, Neoplastic; Mice; MicroRNAs; Myocardium; Neoplasm Proteins; Neoplasms; Oxidative Stress; Rats

2018
Anticancer and multidrug resistance-reversal effects of solanidine analogs synthetized from pregnadienolone acetate.
    Molecules (Basel, Switzerland), 2014, Feb-17, Volume: 19, Issue:2

    Topics: Acetates; Animals; Apoptosis; Cell Cycle Checkpoints; Diosgenin; Doxorubicin; Drug Resistance, Neoplasm; HeLa Cells; Humans; Mice; Neoplasms; Pregnadienediols

2014
In-silico prediction of drug targets, biological activities, signal pathways and regulating networks of dioscin based on bioinformatics.
    BMC complementary and alternative medicine, 2015, Mar-05, Volume: 15

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cell Cycle; Computational Biology; Dioscorea; Diosgenin; DNA Topoisomerases, Type I; Down-Regulation; Drugs, Chinese Herbal; Epidermal Growth Factor; ErbB Receptors; Gene Regulatory Networks; Humans; Male; MAP Kinase Signaling System; Mice; Neoplasms; Phytotherapy; Protein Binding; Rats; Signal Transduction

2015
Study of diosgenin-induced apoptosis kinetics in K562 cells by Sedimentation Field Flow Fractionation.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Jun-15, Volume: 869, Issue:1-2

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Diosgenin; Extracellular Signal-Regulated MAP Kinases; Fractionation, Field Flow; Humans; K562 Cells; Kinetics; Neoplasms

2008
Fenugreek: a naturally occurring edible spice as an anticancer agent.
    Cancer biology & therapy, 2009, Volume: 8, Issue:3

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Diosgenin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Male; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Signal Transduction; Spices; Sulfoxides; Thiocyanates; Trigonella

2009
Chemical characteristics of saponins from Paris fargesii var. brevipetala and cytotoxic activity of its main ingredient, paris saponin H.
    Fitoterapia, 2012, Volume: 83, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Diosgenin; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Liliaceae; Magnoliopsida; Neoplasms; Phytotherapy; Rhizome; Saponins

2012
Solanum incanum and S. heteracanthum as sources of biologically active steroid glycosides: confirmation of their synonymy.
    Fitoterapia, 2012, Volume: 83, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Diosgenin; Glycosides; Humans; Mice; Molecular Structure; Neoplasms; Phytotherapy; Plant Extracts; Saponins; Solanaceous Alkaloids; Solanum; Species Specificity; Spirostans; Steroids

2012
Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression.
    International journal of oncology, 2004, Volume: 25, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Calcium; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cyclooxygenase 2; Cytoplasm; Diosgenin; DNA Fragmentation; Humans; Membrane Potentials; Membrane Proteins; Mitochondria; Neoplasms; Phospholipases A; Phospholipases A2; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2004
Structural identification of methyl protodioscin metabolites in rats' urine and their antiproliferative activities against human tumor cell lines.
    Steroids, 2006, Volume: 71, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Diosgenin; Humans; Male; Models, Molecular; Neoplasms; Rats; Rats, Sprague-Dawley; Saponins

2006
Protodioscin (NSC-698 796): its spectrum of cytotoxicity against sixty human cancer cell lines in an anticancer drug screen panel.
    Planta medica, 2002, Volume: 68, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Dioscorea; Diosgenin; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; K562 Cells; Neoplasms; Plant Extracts; Plant Stems; Saponins; Tumor Cells, Cultured

2002