diosgenin has been researched along with Lung Neoplasms in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 22 (59.46) | 24.3611 |
| 2020's | 11 (29.73) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, W; Jing, S; Li, X; Man, S; Sun, J; Wang, Y; Zhao, C | 1 |
| Cai, E; Chen, R; Fu, H; Ke, K; Li, X; Shen, J; Shen, Z; Shi, X; Song, N; Wan, W; Wang, J; Xie, X; Zhang, Q; Zhang, R; Zhang, Z; Zuo, A | 1 |
| Du, G; Gao, F; Gu, W; Kui, F; Li, W; Liu, Z; Lu, L; Niu, Y; Xi, P; Zhang, Y | 1 |
| Chen, G; Li, J; Ma, L; Wang, X; Wu, W; Wu, Z; Yu, H; Zhang, R; Zhang, Y; Zhu, X; Zhu, Y | 1 |
| da Silva, MF; de Aguiar, AP; de Lima, LVA; de Oliveira, LM; Mantovani, MS; Semprebon, SC; Silva, NO | 1 |
| Cheng, P; Feng, FF; Sun, C; Wang, H; Wang, W | 1 |
| Cai, FY; Fu, M; He, SY; Jing, M; Ju, RJ; Kong, L; Li, XT; Liu, JJ; Liu, XZ; Yao, XM; Zhang, L | 1 |
| Li, W; Liu, X; Liu, Y; Si, Y; Wu, M; Wu, Y; Xiang, K; Xiang, Y; Zhang, L; Zhang, T; Zhao, H; Zhou, T | 1 |
| Ilkar Erdagi, S; Ngwabebhoh, FA; Yildiz, U | 1 |
| Chen, W; Du, B; He, Y; Jin, H; Mao, W; Tan, Y; Wu, S; Yin, H; Zhang, R; Zhao, T | 1 |
| Li, HS; Xu, Y | 1 |
| Chen, L; Jiang, H; Lai, J; Lai, L; Shen, Q; Wang, Y; Wu, Z | 1 |
| Dong, RF; Kong, LY; Liu, MM; Xia, YZ; Yang, L; Zhang, C; Zhang, H; Zhu, ML | 1 |
| Chen, Y; Deng, H; Lou, W; Wang, J; Wu, T; Zhu, KY | 1 |
| Choi, KC; Kim, H; Kim, MK; Kim, YJ; Ko, H; Lee, IH; Lee, KH; Lim, WC | 1 |
| Chen, CY; Lee, H; Wang, L; Wang, YC; Wu, DW; Wu, TC | 1 |
| Cui, J; Gao, W; Ma, L; Man, S; Yang, L; Zhang, L | 1 |
| Chen, W; Jiang, H; Lv, X; Xu, Y; Yang, Q; Zhang, M | 1 |
| Cui, J; Cui, N; Gao, W; Guo, Q; Ma, L; Man, S; Yang, L | 1 |
| Fan, L; Fu, M; Li, G; Li, J; Li, X; Liu, J; Pan, W; Wang, X; Wang, Y; Yang, Y; Yu, Y | 1 |
| Chiou, HL; Hsieh, MJ; Hsieh, YS; Tsai, TL; Wang, CJ | 1 |
| He, Y; Hua, ZC; Huang, QL; Wang, JS; Zhang, P; Zhang, WJ | 1 |
| Han, X; Liu, K; Peng, J; Qi, Y; Sun, H; Wei, Y; Xu, L; Xu, Y; Yin, L | 1 |
| Gholamreza, H; Majid, M; Mohammad, RY; Somayyeh, G; Yousef, R | 1 |
| Feng, J; Jiang, H; Ma, SL; Su, D; Zhao, PJ | 1 |
| Aghazadeh, M; Daroushnejad, H; Ghareghomi, S; Haddadchi, G; Milani, M; Rahmati-Yamchi, M | 1 |
| Feng, J; Jiang, H; Ma, S; Su, D; Zhao, P; Zhu, X | 1 |
| Li, F; Lin, Z; Liu, Y; Liu, Z; Lu, L; Wang, Y; Wu, J; Zhang, G | 1 |
| Du, LW; Feng, JG; Jiang, H; Li, JH; Ma, SL; Song, SC; Zhao, PJ; Zhou, GH; Zhu, XH | 1 |
| Hann, SS; Li, L; Tang, Q; Wu, J; Wu, W; Zheng, F | 1 |
| Chen, W; Gao, W; Li, X; Liu, Z; Man, S; Pan, G; Teng, Y; Wu, M; Yang, K; Yu, P; Zheng, Q | 1 |
| Che, CM; Cheung, YW; He, QY; Ko, BC; Lok, CN; Ma, DL; Siu, FM; Xu, S; Yan, K; Yang, M; Yang, Z | 1 |
| Cheng, H; Dong, A; Fan, J; Kong, M; Xu, R | 1 |
| Gao, W; Huang, L; Liu, C; Liu, Z; Man, S; Yan, L; Zhang, Y | 1 |
| Hu, K; Yao, X | 1 |
| He, X; Liu, B; Qu, G; Su, L; Wang, G; Wang, X; Yao, X | 1 |
| Ikeda, T; Kai, Y; Miyashita, H; Nohara, T | 1 |
37 other study(ies) available for diosgenin and Lung Neoplasms
| Article | Year |
|---|---|
Novel phenanthrene and isocoumarin from the rhizomes of Dioscorea nipponica Makino subsp. rosthornii (Prain et Burkill) C. T. Ting (Dioscoreaceae).
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dioscorea; Humans; Isocoumarins; Lung; Lung Neoplasms; Phenanthrenes; Plant Extracts; Rhizome | 2017 |
Polyphyllin I, a lethal partner of Palbociclib, suppresses non-small cell lung cancer through activation of p21/CDK2/Rb pathway
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Diosgenin; Humans; Lung Neoplasms; Piperazines; Pyridines; Retinoblastoma Protein; Signal Transduction | 2021 |
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Topics: Animals; Diosgenin; Drugs, Chinese Herbal; Lung Neoplasms; Matrix Metalloproteinase 2; Mice; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt | 2022 |
Formosanin C inhibits non-small-cell lung cancer progression by blocking MCT4/CD147-mediated lactate export.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Diosgenin; Humans; Lactic Acid; Lung Neoplasms; Monocarboxylic Acid Transporters | 2023 |
Regulation of cytokinesis and necroptosis pathways by diosgenin inhibits the proliferation of NCI-H460 lung cancer cells.
Topics: Antimitotic Agents; Cell Division; Cytokinesis; Diosgenin; Humans; Lung; Lung Neoplasms; Necroptosis; Reactive Oxygen Species | 2023 |
Inhibitory effects of polyphyllins I and VII on human cisplatin-resistant NSCLC via p53 upregulation and CIP2A/AKT/mTOR signaling axis inhibition.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cisplatin; Diosgenin; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Up-Regulation | 2019 |
RPV-modified epirubicin and dioscin co-delivery liposomes suppress non-small cell lung cancer growth by limiting nutrition supply.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell-Penetrating Peptides; Diosgenin; Epirubicin; Gene Expression Regulation, Neoplastic; Humans; Liposomes; Lung Neoplasms; Male; Mice; Neovascularization, Pathologic; Rats; Xenograft Model Antitumor Assays | 2020 |
Polyphyllin I activates AMPK to suppress the growth of non-small-cell lung cancer via induction of autophagy.
Topics: Allosteric Site; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Enzyme Activators; Female; Humans; Lung Neoplasms; Male; Mice, Nude; Molecular Docking Simulation; Protein Binding; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2020 |
Pickering stabilized nanocellulose-alginate: A diosgenin-mediated delivery of quinalizarin as a potent cyto-inhibitor in human lung/breast cancer cell lines.
Topics: A549 Cells; Alginates; Anthraquinones; Breast Neoplasms; Cellulose; Diosgenin; Drug Delivery Systems; Female; Humans; Lung Neoplasms; MCF-7 Cells | 2020 |
Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma.
Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diosgenin; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases | 2020 |
Inhibition of EZH2 via the STAT3/HOTAIR signalling axis contributes to cell cycle arrest and apoptosis induced by polyphyllin I in human non-small cell lung cancer cells.
Topics: Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Diosgenin; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; Humans; Lung Neoplasms; Real-Time Polymerase Chain Reaction; RNA, Long Noncoding; Signal Transduction; STAT3 Transcription Factor; Up-Regulation | 2020 |
Polyphyllin I reverses the resistance of osimertinib in non-small cell lung cancer cell through regulation of PI3K/Akt signaling.
Topics: Acrylamides; Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2021 |
Polyphyllin I promotes cell death via suppressing UPR-mediated CHOP ubiquitination and degradation in non-small cell lung cancer.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Survival; Diosgenin; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species; Transcription Factor CHOP; Ubiquitination; Unfolded Protein Response | 2021 |
Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Humans; Interleukin-6; Lung Neoplasms; Melanthiaceae; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase Inhibitors; Rhizome; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2017 |
Dioscin suppresses TGF-β1-induced epithelial-mesenchymal transition and suppresses A549 lung cancer migration and invasion.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship; Transforming Growth Factor beta1 | 2017 |
Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Apoptosis; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Diosgenin; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Mutation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Reactive Oxygen Species | 2018 |
Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Curcumin; Diosgenin; Drug Synergism; Fas Ligand Protein; G2 Phase Cell Cycle Checkpoints; Humans; Insulin-Like Growth Factor Binding Protein 1; Lung Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Tumor Necrosis Factor; Saponins; Signal Transduction | 2018 |
Polyphyllin I modulates MALAT1/STAT3 signaling to induce apoptosis in gefitinib-resistant non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Diosgenin; Down-Regulation; Drug Resistance, Neoplasm; Gefitinib; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; RNA, Long Noncoding; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2018 |
The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Beclin-1; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Diosgenin; Drug Synergism; Humans; Lung Neoplasms; Saponins; Signal Transduction | 2019 |
Inhibition of tumor metastasis by targeted daunorubicin and dioscin codelivery liposomes modified with PFV for the treatment of non-small-cell lung cancer.
Topics: A549 Cells; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Daunorubicin; Diosgenin; Drug Delivery Systems; Female; Humans; Liposomes; Lung Neoplasms; Matrix Metalloproteinase 2; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Oligopeptides; Particle Size; Static Electricity; Wound Healing | 2019 |
Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines.
Topics: Annexin A5; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Diosgenin; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Indoles; Lung Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Oncogene Protein v-akt; Organelles; Phosphatidylinositol 3-Kinases; Signal Transduction | 2013 |
[Synergistic apoptotic effect of the combination of diosgenin and TRAIL on non-small-cell lung cancer cell line A549 evaluated with the Chou-Talalay method].
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Drug Synergism; HEK293 Cells; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand | 2013 |
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Large Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosol; Diosgenin; DNA Damage; Humans; Inhibitory Concentration 50; Lung Neoplasms; Microscopy, Electron, Transmission; Mitochondria; Protein Transport; S Phase; Signal Transduction; Small Cell Lung Carcinoma | 2013 |
Diosgenin inhibits hTERT gene expression in the A549 lung cancer cell line.
Topics: Adenocarcinoma; Cell Proliferation; Diosgenin; Humans; Lung Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telomerase; Tumor Cells, Cultured | 2013 |
Paris saponin I induces apoptosis via increasing the Bax/Bcl-2 ratio and caspase-3 expression in gefitinib-resistant non-small cell lung cancer in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Diosgenin; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glucose; Humans; Lung Neoplasms; Male; Mice; Proto-Oncogene Proteins c-bcl-2; Saponins; Xenograft Model Antitumor Assays | 2014 |
Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line.
Topics: Cell Line, Tumor; Diosgenin; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Lung Neoplasms; Phytotherapy; Plant Extracts; RNA; Seeds; Telomerase; Trigonella | 2014 |
Inhibition of cell proliferation by mild hyperthermia at 43˚C with Paris Saponin I in the lung adenocarcinoma cell line PC-9.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Diosgenin; Hot Temperature; Humans; Hyperthermia, Induced; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Saponins | 2015 |
Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with Apoptosis In Vitro and In Vivo.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cyclin B1; Diosgenin; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Saponins; Tumor Suppressor Protein p53; Up-Regulation | 2015 |
Paris Saponins enhance radiosensitivity in a gefitinib-resistant lung adenocarcinoma cell line by inducing apoptosis and G2/M cell cycle phase arrest.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diosgenin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Gefitinib; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Radiation Tolerance; Radiation-Sensitizing Agents; Saponins | 2016 |
Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I.
Topics: A549 Cells; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diosgenin; DNA (Cytosine-5-)-Methyltransferase 1; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Kinase 4; Mice; Mice, Nude; Phosphorylation; Transcription Factor RelA; Xenograft Model Antitumor Assays | 2016 |
Chemosensitizing effect of Paris Saponin I on Camptothecin and 10-hydroxycamptothecin in lung cancer cells via p38 MAPK, ERK, and Akt signaling pathways.
Topics: Blotting, Western; Camptothecin; Cell Line, Tumor; Cell Survival; Diosgenin; Drug Synergism; Humans; Lung Neoplasms; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction | 2017 |
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Lung Neoplasms; Mitochondria; Molecular Chaperones; Proteomics; Saponins; Signal Transduction; Transcription Factor CHOP; Tumor Suppressor Protein p53 | 2008 |
Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Down-Regulation; Humans; Inhibitory Concentration 50; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rhizome; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cisplatin; Diosgenin; Disease Models, Animal; Female; Lung Neoplasms; Male; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Saponins; Wound Healing | 2011 |
The cytotoxicity of methyl protodioscin against human cancer cell lines in vitro.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Survival; Central Nervous System Neoplasms; Colonic Neoplasms; Diosgenin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Lung Neoplasms; Male; Saponins; Tumor Cells, Cultured | 2003 |
Microbial metabolism of methyl protodioscin by Aspergillus niger culture--a new androstenedione producing way from steroid.
Topics: Adenocarcinoma; Androstenedione; Aspergillus niger; Biotransformation; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Molecular Structure; Saponins; Steroids; Uterine Cervical Neoplasms | 2006 |
Efficient synthesis of alpha- and beta-chacotriosyl glycosides using appropriate donors, and their cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Carbohydrate Sequence; Cell Line, Tumor; Diosgenin; Glycosides; Hepatoblastoma; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Tropanes | 2008 |