diosgenin has been researched along with Liver Neoplasms in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 11 (68.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Asai, N; Inoue, M; Kondo, Y; Murayama, M; Naoe, A; Niimi, A; Okada, S; Suzuki, M; Suzuki, T; Takeuchi, T; Tsuchiya, T; Watanabe, S; Yasui, T | 1 |
| Chen, C; Gao, W; Liu, J; Liu, Z; Yu, S; Zeng, P; Zhang, Z | 1 |
| Chen, Z; Lei, S; Liu, H; Meng, Q; Wu, Y; Xia, Z; Xu, J | 1 |
| Chen, S; Lei, Y; Liang, Y; Liu, H; Liu, Y; Meng, J; Qian, B; Qiao, K; Sun, T; Wang, H; Xiao, T; Yang, C; Zhang, H; Zhao, J; Zhong, W; Zhou, H; Zong, S | 1 |
| Chen, B; Chen, Z; Fang, J; Geng, Y; Huang, C; Liu, W; Luo, Q; Ou, Y; Qi, Q; Shi, L; Tang, L; Xia, Y; Yang, D | 1 |
| Chen, D; Fang, L; Han, X; Liu, K; Mao, Z; Peng, J; Qi, Y; Sun, H; Xu, L; Xu, Y; Yin, L | 1 |
| Ao, W; Chen, B; Hou, Y; Ke, J; Liang, Q; Wang, K; Wei, X; Xiao, J; Zhan, Y; Zhou, S; Zhu, P | 1 |
| Cheng, B; Cheng, S; Deng, Z; Du, J; Gao, J; Li, Y; Ling, C; Liu, Q; Wang, X; Zhang, Y | 1 |
| Geng, YD; Kong, LY; Shi, YM; Yang, L; Zhang, C | 1 |
| Gao, W; Liu, J; Liu, Z; Ma, L; Man, S | 1 |
| Du, B; Liu, J; Tan, Y; Wu, Y; Wu, Z; Zeng, X; Zhang, G; Zhang, R; Zhang, W; Zhang, X; Zhao, Y | 1 |
| Fernandez, PP; Hui, KM; Li, F; Rajendran, P; Sethi, G | 1 |
| Bao, YL; Li, YX; Meng, XY; Sun, BT; Wu, Y; Yu, CL; Zheng, LH | 1 |
| Bai, G; Chen, H; Fong, WF; Huang, M; Wang, G; Wang, N; Yang, M; Yao, X; Zhang, J; Zhang, Y | 1 |
| He, X; Liu, B; Qu, G; Su, L; Wang, G; Wang, X; Yao, X | 1 |
| Cheung, JY; Fung, KP; Ho, HP; Kong, SK; Lee, RK; Lei, J; Li, M; Lin, C; Ong, RC; Yu, B | 1 |
16 other study(ies) available for diosgenin and Liver Neoplasms
| Article | Year |
|---|---|
Antitumor effect of polyphyllin D on liver metastases of neuroblastoma.
Topics: Animals; Apoptosis; Cell Line, Tumor; Diosgenin; Liver Neoplasms; Mice; Neuroblastoma; Saponins | 2022 |
Exploring the Effect of Polyphyllin I on Hepatitis B Virus-related Liver Cancer through Network Pharmacology and in vitro Experiments.
Topics: Diosgenin; Drugs, Chinese Herbal; Hepatitis B virus; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Molecular Docking Simulation; Network Pharmacology | 2022 |
Diosgenin inhibited the expression of TAZ in hepatocellular carcinoma.
Topics: Acyltransferases; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Liver Neoplasms; Structure-Activity Relationship; Transcription Factors; Wound Healing | 2018 |
Polyphyllin I suppresses the formation of vasculogenic mimicry via Twist1/VE-cadherin pathway.
Topics: Animals; Antigens, CD; Cadherins; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Diosgenin; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Transcription, Genetic; Twist-Related Protein 1 | 2018 |
Role of the Death Receptor and Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 12; Caspase 8; Cell Line, Tumor; Cell Survival; Diosgenin; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; Necrosis; Receptors, Death Domain; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Diosgenin; DNA Damage; Glycolysis; Humans; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Phosphoric Monoester Hydrolases; Rats, Wistar; RNA, Small Interfering; Tumor Suppressor Protein p53 | 2019 |
Dioscin Inhibits the Invasion and Migration of Hepatocellular Carcinoma HepG2 Cells by Reversing TGF-β1-Induced Epithelial-Mesenchymal Transition.
Topics: Cell Movement; Cell Proliferation; Diosgenin; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Signal Transduction; Transforming Growth Factor beta1 | 2019 |
Diosgenin induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diosgenin; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt | 2015 |
Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells.
Topics: Apoptosis; Autophagy; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Chloroquine; Diosgenin; Drug Synergism; Humans; Liver Neoplasms; Molecular Structure; Saponins; Signal Transduction | 2015 |
A synergistic antitumor effect of polyphyllin I and formosanin C on hepatocarcinoma cells.
Topics: Apoptosis; Cell Cycle; Diosgenin; Drug Screening Assays, Antitumor; Drug Synergism; Hep G2 Cells; Humans; Liver Neoplasms; Saponins | 2016 |
Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Diosgenin; DNA Fragmentation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2016 |
Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Doxorubicin; Flow Cytometry; Humans; Immunohistochemistry; Liver Neoplasms; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor | 2010 |
Reversal effect of Dioscin on multidrug resistance in human hepatoma HepG2/adriamycin cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Diosgenin; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, MDR; Genetic Vectors; HEK293 Cells; Hep G2 Cells; Hepatocytes; High-Throughput Screening Assays; Humans; Liver Neoplasms; Plasmids; RNA, Messenger | 2011 |
Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; CDC2-CDC28 Kinases; Cell Division; Cell Line, Tumor; Cyclin B; Cyclin B1; Diosgenin; G2 Phase; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Saponins | 2006 |
Microbial metabolism of methyl protodioscin by Aspergillus niger culture--a new androstenedione producing way from steroid.
Topics: Adenocarcinoma; Androstenedione; Aspergillus niger; Biotransformation; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Molecular Structure; Saponins; Steroids; Uterine Cervical Neoplasms | 2006 |
Polyphyllin D induces mitochondrial fragmentation and acts directly on the mitochondria to induce apoptosis in drug-resistant HepG2 cells.
Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspases; Diosgenin; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Saponins; Tumor Cells, Cultured | 2008 |