diosgenin has been researched along with Inflammation in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 19 (54.29) | 24.3611 |
| 2020's | 16 (45.71) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, J; Huang, Y; Li, J; Ma, L; Su, L; Tang, Y; Wang, R; Wu, YH; Yang, GX; Zhang, L; Zheng, LL; Zhou, LC | 1 |
| Huang, W; Huang, Y; Ma, L; Wang, R; Yang, G | 1 |
| Jayaraman, S; Kumar, PK; Pari, L; Piramanayagam, S; Prasad, M; Rajagopal, P; Veeraraghavan, VP | 1 |
| Guan, T; Hu, M; Huang, S; Jin, S; Liu, X; Liu, Y; Wang, S | 1 |
| Gao, M; Qi, Y; Wang, J; Xu, L; Yin, L; Zhang, Z; Zhao, X | 1 |
| Mao, F; Wu, A | 1 |
| Wang, D; Wang, X | 1 |
| Deng, S; Jin, S; Li, D; Li, J; Liu, X; Liu, Y; Zhu, T | 1 |
| Feng, YN; Liang, PP; Ma, CQ; Sun, FC; Yin, GL; Zhang, FX; Zhang, SZ | 1 |
| Cui, JJ; Huang, ZY; Li, CF; Wu, JB; Xie, YH; Xu, GH; Yi, LT; Zhang, MM | 1 |
| Jin, Y; Liu, K; Ma, X; Sun, H; Wang, C; Wang, J; Xie, T; Yang, Q | 1 |
| Li, Y; Wang, M; Yang, T | 1 |
| Gan, Q; Hu, J; Huang, Q; Lou, G; Peng, C; Wang, J; Xiong, H; Zheng, S | 1 |
| Baluchnejadmojarad, T; Khanizadeh, AM; Mohamadi-Zarch, SM; Nourabadi, D; Roghani, M | 1 |
| Afshin-Majd, S; Baluchnejadmojarad, T; Kiasalari, Z; Mahmoudi, N; Naderi, G; Rahmani, T; Roghani, M; Sanaierad, A | 1 |
| Han, J; Jiang, D; Li, F; Li, W; Shi, G; Xie, Y | 1 |
| Ahn, KS; Arya, A; Banik, K; Boruah, M; Dutta, U; Harsha, C; Kunnumakkara, AB; Mao, X; Parama, D; Rana, V; Thakur, KK; Yachna, K | 1 |
| Su, F; Tang, S; Zhu, S | 1 |
| Han, X; Liu, K; Ma, X; Peng, J; Qi, Y; Qiao, Y; Tang, Z; Tao, X; Xu, L; Xu, Y; Yin, L | 1 |
| Cao, H; Liu, HJ; Qiao, ZY; Wang, HW; Xu, YW | 1 |
| Cao, F; Cao, YK; Li, CW; Li, Y; Wang, YB; Wu, Q; Xu, B; Yang, B; Zhang, J; Zhao, H | 1 |
| He, L; Li, D; Sun, D; Wu, W; Yang, S; Zhu, T | 1 |
| Liu, M; Lu, J; Sun, H; Wang, S; Zhang, T | 1 |
| Baluchnejadmojarad, T; Khosravi, Z; Roghani, M; Sedaghat, R | 1 |
| El-Sheikh, AAK; Morsy, MA; Nair, AB; Patel, SS; Savjani, JK; Shah, JN; Venugopala, KN | 1 |
| Araújo, AA; Barreto, RS; de Albuquerque, RL; de Almeida, EB; Lima, AK; Lima, CM; Melo, MG; Moraes, VR; Nogueira, PC; Oliveira, DL; Oliveira, ER; Quintans-Júnior, LJ; Serafini, MR | 1 |
| Badalzadeh, R; Ebrahimi, H; Mohammadi, M; Yousefi, B | 1 |
| Aiyelaagbe, OO; Bawankule, DU; Hamid, AA; Khan, F; Kumar, A; Maurya, AK; Negi, AS; Prakash, O; Singh, M | 1 |
| Agha, AM; Ahmed, LA; Obaid, AA; Zaki, HF | 1 |
| Han, X; Lin, Y; Peng, J; Qi, Y; Tao, X; Wan, X; Xu, L; Xu, Y; Yin, L | 1 |
| Han, X; Lin, Y; Liu, K; Liu, M; Peng, J; Qi, Y; Sun, H; Xu, L; Xu, Y; Yao, J; Yin, L; Zhao, Y | 1 |
| Fuller, S; Stephens, JM | 1 |
| Guo, Z; Ito, Y; Sun, W; Xian, L; Xue, X; Zhang, X | 1 |
| Baluchnejadmojarad, T; Kiasalari, Z; Mahmoudi, N; Rahmani, T; Roghani, M | 1 |
| Goto, T; Hirai, S; Hoshino, S; Kawada, T; Lee, JY; Mizoguchi, N; Nakano, Y; Narukami, T; Shono, J; Takahashi, N; Taketani, K; Tsuge, N; Uemura, T | 1 |
5 review(s) available for diosgenin and Inflammation
| Article | Year |
|---|---|
Diosgenin and Its Analogs: Potential Protective Agents Against Atherosclerosis.
Topics: Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Diosgenin; Humans; Inflammation | 2022 |
Therapeutic potential and research progress of diosgenin for lipid metabolism diseases.
Topics: Animals; Antioxidants; Diosgenin; Inflammation; Lipid Metabolism; Oxidative Stress | 2022 |
The role of diosgenin in diabetes and diabetic complications.
Topics: Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus; Diosgenin; Female; Glycolipids; Hep G2 Cells; Humans; Hypoglycemia; Inflammation; Insulin; Insulin Resistance; Male; Mice; Oxidative Stress; Plants; Rabbits; Rats; Steroids | 2020 |
Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases.
Topics: Animals; Biological Availability; Cardiovascular Diseases; Chemical Phenomena; Chronic Disease; Diosgenin; Humans; Inflammation; Neoplasms; Nervous System Diseases; Phytotherapy; PubMed; Seeds; Signal Transduction; Trigonella | 2020 |
Diosgenin, 4-hydroxyisoleucine, and fiber from fenugreek: mechanisms of actions and potential effects on metabolic syndrome.
Topics: Biomarkers; Dietary Fiber; Diosgenin; Humans; Inflammation; Isoleucine; Metabolic Syndrome; Phytotherapy; Plant Extracts; Trigonella | 2015 |
30 other study(ies) available for diosgenin and Inflammation
| Article | Year |
|---|---|
Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Carbamates; Cell Line, Tumor; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Galactose; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Molecular Structure; Neuroprotective Agents; Oxidative Stress; Protein Aggregates; Structure-Activity Relationship | 2020 |
Design and synthesis of novel diosgenin-triazole hybrids targeting inflammation as potential neuroprotective agents.
Topics: Alzheimer Disease; Animals; Cell Line; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Inflammation; Lipopolysaccharides; Molecular Conformation; Neuroprotective Agents; Nitric Oxide; Rats; Structure-Activity Relationship; Triazoles | 2021 |
Diosgenin inhibits ER stress-induced inflammation in aorta via iRhom2/TACE mediated signaling in experimental diabetic rats: An in vivo and in silico approach.
Topics: ADAM17 Protein; Animals; Aorta; Cytokines; Diabetes Mellitus, Experimental; Diosgenin; Endoplasmic Reticulum Stress; Hyperglycemia; Hypertension; Inflammation; Lipids; Male; Molecular Docking Simulation; Oxidative Stress; Rats; Streptozocin; Tumor Necrosis Factor-alpha | 2022 |
Dioscin Alleviates Cisplatin-Induced Mucositis in Rats by Modulating Gut Microbiota, Enhancing Intestinal Barrier Function and Attenuating TLR4/NF-κB Signaling Cascade.
Topics: Animals; Cisplatin; Diosgenin; Gastrointestinal Microbiome; Humans; Inflammation; Mucositis; Myeloid Differentiation Factor 88; NF-kappa B; Rats; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Dioscin alleviates myocardial infarction injury via regulating BMP4/NOX1-mediated oxidative stress and inflammation.
Topics: Animals; Bone Morphogenetic Protein 4; Diosgenin; Hypoxia; Inflammation; Interleukin-6; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C57BL; Myocardial Infarction; NADPH Oxidase 1; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2022 |
Polyphyllin I alleviates lipopolysaccharide-induced inflammation reduces pyroptosis in BEAS-2B and HPAEC cells by inhibiting NF-κB signaling.
Topics: Diosgenin; Endothelial Cells; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; NF-kappa B; Pulmonary Artery; Pyroptosis; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2022 |
Dioscin ameliorates cisplatin-induced intestinal toxicity by mitigating oxidative stress and inflammation.
Topics: Animals; Antioxidants; Cisplatin; Diosgenin; Hydrogen Peroxide; Inflammation; NF-E2-Related Factor 2; Oxidative Stress; Rats | 2022 |
Gut microbiota mediated inflammation, neuroendocrine and neurotrophic functions involved in the antidepressant-like effects of diosgenin in chronic restraint stress.
Topics: Animals; Antidepressive Agents; Diosgenin; Female; Gastrointestinal Microbiome; Hypothalamo-Hypophyseal System; Inflammation; Male; Mice; Pituitary-Adrenal System | 2023 |
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Cells, Cultured; Diosgenin; Endothelial Cells; Estrogen Receptor alpha; Female; Humans; Inflammation; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Ovariectomy; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Plant Extracts; Postmenopause; Receptors, LDL; Signal Transduction | 2019 |
Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK.
Topics: Adult; Atherosclerosis; CD36 Antigens; Dendritic Cells; Diosgenin; Female; Gene Expression Regulation; Glucose; Humans; Inflammation; Interleukin-10; Interleukin-12; Interleukin-6; Lipoproteins, LDL; Male; p38 Mitogen-Activated Protein Kinases; Scavenger Receptors, Class A; Scavenger Receptors, Class E | 2020 |
Protective effect of diosgenin on LPS/D-Gal-induced acute liver failure in C57BL/6 mice.
Topics: Animals; Diosgenin; Disease Models, Animal; Inflammation; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred C57BL | 2020 |
Diosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms.
Topics: Animals; Behavior, Animal; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diosgenin; Hippocampus; Inflammation; Learning; Neuroprotective Agents; Oxidative Stress; Rats | 2021 |
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.
Topics: Animals; Arthritis, Gouty; Diosgenin; Humans; Inflammasomes; Inflammation; Male; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Toll-Like Receptor 4; Uric Acid | 2021 |
Dioscin inhibits ischemic stroke‑induced inflammation through inhibition of the TLR4/MyD88/NF‑κB signaling pathway in a rat model.
Topics: Animals; Brain Ischemia; Diosgenin; HMGB1 Protein; Humans; Inflammation; Interleukin-1 Receptor-Associated Kinases; Myeloid Differentiation Factor 88; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Stroke; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Transforming Growth Factor beta1 | 2018 |
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Topics: Animals; Diosgenin; Disease Models, Animal; Fibrosis; Fructose; Inflammation; Kidney; Lipid Metabolism; Male; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Renal Insufficiency, Chronic | 2018 |
Diosgenin Protects Rats from Myocardial Inflammatory Injury Induced by Ischemia-Reperfusion.
Topics: Animals; Cardiotonic Agents; Diosgenin; Heart Function Tests; Inflammation; Interleukin-1beta; Male; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Peroxidase; Phosphorylation; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2018 |
Dioscin protects against coronary heart disease by reducing oxidative stress and inflammation via Sirt1/Nrf2 and p38 MAPK pathways.
Topics: Animals; Coronary Disease; Diosgenin; Inflammation; Male; MAP Kinase Signaling System; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Sirtuin 1; Swine; Swine, Miniature | 2018 |
Polyphyllin I Inhibits Propionibacterium acnes-Induced Inflammation In Vitro.
Topics: Acne Vulgaris; Cell Line; Cytokines; Diosgenin; Humans; Inflammation; Keratinocytes; MAP Kinase Signaling System; NF-kappa B; Propionibacterium acnes | 2019 |
Protective effects of dioscin against cartilage destruction in a monosodium iodoacetate (MIA)-indcued osteoarthritis rat model.
Topics: Animals; Apoptosis; beta Catenin; Cartilage, Articular; Diosgenin; Disease Models, Animal; Extracellular Matrix; Inflammation; Iodoacetates; Male; Osteoarthritis; Oxidative Stress; PPAR gamma; Protective Agents; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway | 2018 |
Diosgenin ameliorates testicular damage in streptozotocin-diabetic rats through attenuation of apoptosis, oxidative stress, and inflammation.
Topics: Animals; Apoptosis; Cytokines; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diosgenin; Disease Models, Animal; Humans; Inflammation; Inflammation Mediators; Male; Malondialdehyde; Oxidative Stress; Rats; Sperm Count; Spermatozoa; Testis; Testosterone | 2019 |
Computational and Biological Comparisons of Plant Steroids as Modulators of Inflammation through Interacting with Glucocorticoid Receptor.
Topics: Animals; Anti-Inflammatory Agents; Croton Oil; Diosgenin; Ear Diseases; Edema; Enzyme-Linked Immunosorbent Assay; Glycyrrhetinic Acid; Inflammation; Interleukin-6; Mice; Molecular Docking Simulation; Phytosterols; Pregnenediones; Rats; Receptors, Glucocorticoid; Software; Thymus Gland; Triterpenes; Tumor Necrosis Factor-alpha; Withanolides | 2019 |
Bioassay-guided evaluation of Dioscorea villosa - an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Biological Assay; Dioscorea; Diosgenin; Female; Formaldehyde; Inflammation; Leukocytes; Male; Mice; Pain; Phytotherapy; Plant Extracts; Rats; Rats, Wistar | 2013 |
Diosgenin attenuates inflammatory response induced by myocardial reperfusion injury: role of mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Diosgenin; Enzyme-Linked Immunosorbent Assay; Inflammation; Interleukin-1beta; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Potassium Channels; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2014 |
Synthesis of diosgenin analogues as potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Diosgenin; Female; Inflammation; Lipopolysaccharides; Liver; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mouth Diseases; Sepsis | 2014 |
Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Caspase 3; Diosgenin; Glutathione; Heart Ventricles; Hypertension, Pulmonary; Inflammation; Lung; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Protective Agents; Pulmonary Artery; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2014 |
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Diosgenin; Dose-Response Relationship, Drug; Inflammation; Liver; Male; Nitrogen; Oxidative Stress; Phosphorylation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Warm Ischemia | 2014 |
Potent effects of dioscin against obesity in mice.
Topics: Animals; Autophagy; Blood Glucose; Body Weight; Cholesterol; Diet, High-Fat; Diosgenin; Energy Metabolism; Fatty Acids; Glucose Tolerance Test; Inflammation; Liver; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidative Stress; Phosphorylation; Signal Transduction; Triglycerides | 2015 |
Potential neuroprotection of protodioscin against cerebral ischemia-reperfusion injury in rats through intervening inflammation and apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Diosgenin; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Male; Neuroprotection; Neuroprotective Agents; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins | 2016 |
Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diosgenin; Ganglia, Spinal; Inflammation; Male; Malondialdehyde; Neuralgia; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin; Superoxide Dismutase | 2017 |
Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Blood Glucose; Cell Differentiation; Diosgenin; Disease Models, Animal; Glucose; Inflammation; Insulin Resistance; Male; Mice; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; RNA, Messenger; Saponins; Trigonella | 2010 |