diosgenin has been researched along with Colonic Neoplasms in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arya, P; Kumar, P | 1 |
| Cheng, B; Cui, Y; Hou, L; Huang, L; Li, S; Shen, X; Xu, D | 1 |
| Chen, H; Han, X; Liu, K; Peng, J; Qi, Y; Xu, L; Xu, Y; Yin, L; Zhao, Y | 1 |
| Hu, X; Jiang, L; Qing, Y; Tong, Q; Wu, X; Wu, Y | 1 |
| Mabuchi, R; Miyoshi, N; Nagasawa, T; Ohshima, H; Tanaka, T; Wakabayashi, K; Yasui, Y | 1 |
| Hu, K; Yao, X | 1 |
| Cai, B; Cui, CB; Liu, HW; Wang, SL; Wu, CF; Yao, XS | 1 |
| Patlolla, JM; Raju, J; Rao, CV; Swamy, MV | 1 |
| Bird, RP; Raju, J | 1 |
| Chai, H; Cordell, GA; Farnsworth, NR; Hollingshead, MG; Kardono, LB; Kinghorn, AD; Lantvit, D; Lee, IS; Mayo, JG; Mi, Q; Ngassapa, O; Peraza-Sánchez, S; Pezzuto, JM; Reyes-Lim, E; Riswan, S; Zhao, W | 1 |
1 review(s) available for diosgenin and Colonic Neoplasms
| Article | Year |
|---|---|
Diosgenin a steroidal compound: An emerging way to cancer management.
Topics: Apoptosis; Colonic Neoplasms; Diosgenin; Humans; Male | 2021 |
9 other study(ies) available for diosgenin and Colonic Neoplasms
| Article | Year |
|---|---|
Dioscin inhibits colon cancer cells' growth by reactive oxygen species-mediated mitochondrial dysfunction and p38 and JNK pathways.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; Diosgenin; HT29 Cells; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitochondria; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species | 2018 |
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Topics: Apoptosis; Cell Cycle; Cell Shape; Cell Survival; Colonic Neoplasms; Diosgenin; DNA Damage; HCT116 Cells; Humans; Isotope Labeling; Nitric Oxide; Nitric Oxide Synthase Type II; Proteins; Proteome; Proteomics; Reactive Oxygen Species | 2014 |
Dioscin inhibits colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK signaling pathways.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Diosgenin; Dose-Response Relationship, Drug; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Male; MAP Kinase Signaling System; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Neovascularization, Physiologic; Phosphorylation; Proto-Oncogene Proteins c-akt; Time Factors; Tumor Burden; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
Chemoprevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by freeze-dried yam sanyaku and its constituent diosgenin.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Dioscorea; Diosgenin; Disease Models, Animal; Gene Expression Profiling; Male; Mice; Mice, Inbred ICR; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
The cytotoxicity of methyl protodioscin against human cancer cell lines in vitro.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Survival; Central Nervous System Neoplasms; Colonic Neoplasms; Diosgenin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Lung Neoplasms; Male; Saponins; Tumor Cells, Cultured | 2003 |
Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 4)-beta-D-glucopyranoside obtained as a new anticancer agent from Dioscorea futschauensis induces apoptosis on human colon carcinoma HCT-15 cells via mitochondria-controlled apoptotic pathway.
Topics: Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Cell Line, Tumor; Colonic Neoplasms; Cytochromes c; Dioscorea; Diosgenin; Down-Regulation; Flow Cytometry; Humans; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Saponins | 2004 |
Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells.
Topics: Animals; Apoptosis; Azoxymethane; Cell Division; Colonic Neoplasms; Diosgenin; Disease Models, Animal; History, Early Modern 1451-1600; HT29 Cells; Humans; Intestinal Mucosa; Male; Plant Extracts; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344; Reference Values; Saponins; Sensitivity and Specificity; Trigonella; Tumor Cells, Cultured | 2004 |
Diosgenin, a naturally occurring steroid [corrected] saponin suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinoma cells.
Topics: Apoptosis; beta Catenin; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Diosgenin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oncogene Protein p21(ras); Saponins | 2007 |
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
Topics: Animals; Biological Factors; Colonic Neoplasms; Diosgenin; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 3-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; KB Cells; Leukemia P388; Male; Melanoma; Mice; Molecular Structure; Naphthoquinones; Ovarian Neoplasms; Paclitaxel; Polymers; Prostatic Neoplasms; Triterpenes; Tumor Cells, Cultured | 2002 |