Page last updated: 2024-08-26

diosgenin and Breast Neoplasms

diosgenin has been researched along with Breast Neoplasms in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (40.00)29.6817
2010's6 (30.00)24.3611
2020's6 (30.00)2.80

Authors

AuthorsStudies
Li, H; Liu, J; Liu, W; Liu, Y; Mao, A; Pan, G; Wei, C1
Liu, Y; Lu, JF; Wen, J; Xiong, YL; Zhang, L; Zhang, T1
Dat, NT; Dung, LV; Duyen, NT; Ha, DT; Hien, TT; Khoi, NM; Lee, KY; Long, PQ; Phong, NV; Vinh, LB1
Ilkar Erdagi, S; Ngwabebhoh, FA; Yildiz, U1
Cai, FY; Fu, M; He, SY; Jing, M; Ju, RJ; Kong, L; Li, XT; Liu, JJ; Liu, XZ; Niu, FJ; Yao, XM; Zhang, L1
Liu, Y; Wu, X; Xu, G; Yan, J; Zhou, Z1
Chen, H; Gao, Y; He, Z; Li, G; Sun, J; Zhang, L; Zhu, H1
Jang, JH; Kim, EA; Kim, JY; Kim, S; Lee, TJ; Lee, YH; Sohn, HY; Song, IH; Sung, EG1
Avasthi, A; Bellare, J; Chopade, BA; Derle, A; Dhavale, DD; Ghosh, S; Gorain, M; Kale, S; Kale, T; Kitture, R; Kundu, GC; Markad, P; More, P1
Ali, Z; Aumsuwan, P; Avula, B; Dasmahapatra, AK; Helferich, WG; Katzenellenbogen, BS; Khan, IA; Khan, SI; Shariat-Madar, Z; Walker, LA1
Huo, X; Liu, K; Liu, Q; Liu, Z; Meng, Q; Peng, J; Sun, H; Sun, P; Wang, C; Wang, L1
Fu, RQ; Gao, N; Hu, XY; Huang, C; Li, GB; Li, YN; Liu, X; Liu, YX; Shen, HM; Zhang, HW; Zhang, R; Zhang, YH; Zhou, J1
Anchoori, RK; Carducci, MA; Davidson, N; Hidalgo, M; Jimeno, A; Kachhap, S; Khan, SR; Shabbeer, S; Sobolewski, M1
Damodaran, C; Koduru, S; Kumar, R; Kyprianou, N; Srinivasan, S; Venguswamy, G1
Jiang, ZH; Kaskiw, MJ; Mok, M; Pycko, R; Tassotto, ML; Th'ng, J; Tokar, SL1
Friedman, M; Henika, PR; Mackey, BE1
Guo, M; Li, J; Liu, S; Liu, X; Liu, Y; Yao, S1
Chung-Wai, TM; Eng-Choon, VO; Fung, KP; Kong, SK; Lee, MS; Nai-Ching, HW; Yu, B; Yuet-Wa, JC1
He, X; Liu, B; Qu, G; Su, L; Wang, G; Wang, X; Yao, X1
Chiang, CT; Lin, JK; Tsai, SJ; Way, TD1

Other Studies

20 other study(ies) available for diosgenin and Breast Neoplasms

ArticleYear
Polyphyllin D induces apoptosis and protective autophagy in breast cancer cells through JNK1-Bcl-2 pathway.
    Journal of ethnopharmacology, 2022, Jan-10, Volume: 282

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diosgenin; Female; Humans; MAP Kinase Signaling System; Melanthiaceae; Mitogen-Activated Protein Kinase 8; Proto-Oncogene Proteins c-bcl-2; Saponins

2022
[Mechanism of polyphyllin Ⅰ targeting EGFR to affect proliferation and apoptosis of human breast cancer cells].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:3

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diosgenin; ErbB Receptors; Female; Humans; Molecular Docking Simulation

2022
Steroid glycosides isolated from Paris polyphylla var. chinensis aerial parts and paris saponin II induces G1/S-phase MCF-7 cell cycle arrest.
    Carbohydrate research, 2022, Volume: 519

    Topics: Breast Neoplasms; Cell Cycle Checkpoints; Diosgenin; Female; Humans; Liliaceae; MCF-7 Cells; Molecular Docking Simulation; Plant Components, Aerial; Plant Extracts; Saponins

2022
Pickering stabilized nanocellulose-alginate: A diosgenin-mediated delivery of quinalizarin as a potent cyto-inhibitor in human lung/breast cancer cell lines.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 109

    Topics: A549 Cells; Alginates; Anthraquinones; Breast Neoplasms; Cellulose; Diosgenin; Drug Delivery Systems; Female; Humans; Lung Neoplasms; MCF-7 Cells

2020
GGP modified daunorubicin plus dioscin liposomes inhibit breast cancer by suppressing epithelial-mesenchymal transition.
    Drug development and industrial pharmacy, 2020, Volume: 46, Issue:6

    Topics: Breast Neoplasms; Cell Line, Tumor; Daunorubicin; Diosgenin; Epithelial-Mesenchymal Transition; Humans; Liposomes

2020
Diosgenin Exerts Antitumor Activity via Downregulation of Skp2 in Breast Cancer Cells.
    BioMed research international, 2020, Volume: 2020

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Diosgenin; Down-Regulation; Female; Humans; MCF-7 Cells; S-Phase Kinase-Associated Proteins

2020
Diosgenin inhibits the migration of human breast cancer MDA-MB-231 cells by suppressing Vav2 activity.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, May-15, Volume: 21, Issue:6

    Topics: Actins; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Dioscorea; Diosgenin; Humans; Phosphorylation; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-vav

2014
Dioscin induces caspase-independent apoptosis through activation of apoptosis-inducing factor in breast cancer cells.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Breast Neoplasms; Caspases; Cell Line, Tumor; Diosgenin; Female; Humans; Inhibitor of Apoptosis Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2

2014
Diosgenin Functionalized Iron Oxide Nanoparticles as Novel Nanomaterial Against Breast Cancer.
    Journal of nanoscience and nanotechnology, 2015, Volume: 15, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Diosgenin; Drug Carriers; Humans; Magnetite Nanoparticles; MCF-7 Cells

2015
The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro.
    Archives of biochemistry and biophysics, 2016, Feb-01, Volume: 591

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dioscorea; Diosgenin; Dose-Response Relationship, Drug; Humans; MCF-7 Cells; Neoplasm Invasiveness; Phytosterols; Plant Extracts; Plant Roots; Saponins; Treatment Outcome

2016
Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1.
    Scientific reports, 2016, 06-22, Volume: 6

    Topics: ATP Binding Cassette Transporter, Subfamily B; Autophagy; Breast Neoplasms; Cell Proliferation; Diosgenin; Down-Regulation; Doxorubicin; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; NF-kappa B; Promoter Regions, Genetic; Signal Transduction

2016
Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels.
    Oncotarget, 2017, Feb-07, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autophagy; Breast Neoplasms; Diosgenin; Dose-Response Relationship, Drug; Dynamins; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; GTP Phosphohydrolases; Humans; MCF-7 Cells; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Mitophagy; Protein Kinases; RNA Interference; Signal Transduction; Time Factors; Transfection; Tumor Burden; Ubiquitin-Protein Ligases; Up-Regulation; Xenograft Model Antitumor Assays

2017
Fenugreek: a naturally occurring edible spice as an anticancer agent.
    Cancer biology & therapy, 2009, Volume: 8, Issue:3

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Diosgenin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Male; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Signal Transduction; Spices; Sulfoxides; Thiocyanates; Trigonella

2009
Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells.
    International journal of cancer, 2009, Aug-15, Volume: 125, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Cycle; Diosgenin; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; MAP Kinase Kinase Kinases; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; raf Kinases; Receptors, Estrogen; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Structural analogues of diosgenyl saponins: synthesis and anticancer activity.
    Bioorganic & medicinal chemistry, 2009, Nov-15, Volume: 17, Issue:22

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diosgenin; Disaccharides; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Monosaccharides; Saponins; Uterine Cervical Neoplasms

2009
Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2003, Volume: 41, Issue:1

    Topics: Abortion, Veterinary; Adenocarcinoma; Animals; Body Weight; Breast Neoplasms; Cell Division; Diosgenin; Dose-Response Relationship, Drug; Female; Fertility; Hepatomegaly; Humans; Litter Size; Liver; Mice; Organ Size; Pregnancy; Pregnancy Outcome; Random Allocation; Receptors, Estrogen; Solanaceous Alkaloids; Structure-Activity Relationship; Tomatine; Tumor Cells, Cultured

2003
Electrochemical study of breast cancer cells MCF-7 and its application in evaluating the effect of diosgenin.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2005, Volume: 21, Issue:5

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diosgenin; Electrochemistry; Female; Humans; Indicators and Reagents; Potentiometry; Trypan Blue

2005
Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft.
    Cancer biology & therapy, 2005, Volume: 4, Issue:11

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Saponins; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2005
Microbial metabolism of methyl protodioscin by Aspergillus niger culture--a new androstenedione producing way from steroid.
    The Journal of steroid biochemistry and molecular biology, 2006, Volume: 100, Issue:1-3

    Topics: Adenocarcinoma; Androstenedione; Aspergillus niger; Biotransformation; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Molecular Structure; Saponins; Steroids; Uterine Cervical Neoplasms

2006
Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation.
    FEBS letters, 2007, Dec-22, Volume: 581, Issue:30

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diosgenin; Down-Regulation; Drug Screening Assays, Antitumor; Fatty Acid Synthases; Humans; JNK Mitogen-Activated Protein Kinases; Palmitic Acid; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Solanaceous Alkaloids; Tomatine; TOR Serine-Threonine Kinases; Up-Regulation

2007