Page last updated: 2024-08-26

diosgenin and Atherogenesis

diosgenin has been researched along with Atherogenesis in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Bao, R; Chen, B; Chen, Q; Han, L; Liu, M; Pan, J; Wang, D; Wang, T; Wang, W; Wu, Y; Yu, H; Zhang, Y1
Wang, D; Wang, X1
Jin, Y; Liu, K; Ma, X; Sun, H; Wang, C; Wang, J; Xie, T; Yang, Q1
Jiang, JG; Wu, FC1
Binesh, A; Devaraj, H; Devaraj, SN2
Li, Y; Wang, M; Yang, T1
Sun, B; Xiao, J; Yang, D; Yin, YZ1
He, LY; Li, RL; Shen, GD; Wang, P; Yang, JL1
Cayabyab, FS; He, PP; Li, L; Liu, D; Lv, YC; Ouyang, XP; Tan, YL; Tang, CK; Tang, YY; Xie, W; Yang, J; Yao, F; Zhang, M; Zheng, XL1
Moura, ML; Pereira de Oliveira, A; Rolim, HM1
Fan, MJ; Hsieh, WT; Liu, FC; Pan, CH; Sheu, MJ; Tsai, CH; Wu, CH1

Reviews

3 review(s) available for diosgenin and Atherogenesis

ArticleYear
Diosgenin and Its Analogs: Potential Protective Agents Against Atherosclerosis.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Diosgenin; Humans; Inflammation

2022
Effects of diosgenin and its derivatives on atherosclerosis.
    Food & function, 2019, Nov-01, Volume: 10, Issue:11

    Topics: Animals; Atherosclerosis; Dioscorea; Diosgenin; Endothelium, Vascular; Humans; Plant Extracts; Trigonella

2019
Cardioprotector Activity of an Esteroidal Saponin: A Scientific and Technological Prospection.
    Recent patents on biotechnology, 2017, Volume: 11, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Cardiotonic Agents; Diosgenin; Disease Models, Animal; Dyslipidemias; Humans; Hypertension; Mice; Patents as Topic; Rats; Saponins

2017

Other Studies

9 other study(ies) available for diosgenin and Atherogenesis

ArticleYear
Dioscin Ameliorates Hyperuricemia-Induced Atherosclerosis by Modulating of Cholesterol Metabolism through FXR-Signaling Pathway.
    Nutrients, 2022, May-09, Volume: 14, Issue:9

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diosgenin; Hyperuricemia; Liver; Mice; Signal Transduction

2022
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
    Pharmacological research, 2019, Volume: 148

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Cells, Cultured; Diosgenin; Endothelial Cells; Estrogen Receptor alpha; Female; Humans; Inflammation; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Ovariectomy; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Plant Extracts; Postmenopause; Receptors, LDL; Signal Transduction

2019
Expression of chemokines in macrophage polarization and downregulation of NFκB in aorta allow macrophage polarization by diosgenin in atherosclerosis.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:2

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Atherosclerosis; CD36 Antigens; Cell Differentiation; Cell Polarity; Cyclooxygenase 2; Cytokines; Dexamethasone; Diet, Atherogenic; Dioscorea; Diosgenin; Humans; Lipoproteins, LDL; Macrophages; Male; Monocytes; Plant Extracts; Rats; Signal Transduction; THP-1 Cells; Transcription Factor RelA

2020
Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK.
    Molecular medicine reports, 2020, Volume: 21, Issue:1

    Topics: Adult; Atherosclerosis; CD36 Antigens; Dendritic Cells; Diosgenin; Female; Gene Expression Regulation; Glucose; Humans; Inflammation; Interleukin-10; Interleukin-12; Interleukin-6; Lipoproteins, LDL; Male; p38 Mitogen-Activated Protein Kinases; Scavenger Receptors, Class A; Scavenger Receptors, Class E

2020
Estrogenic and anti-inflammatory effects of pseudoprotodioscin in atherosclerosis-prone mice: Insights into endothelial cells and perivascular adipose tissues.
    European journal of pharmacology, 2020, Feb-15, Volume: 869

    Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Apoptosis; Atherosclerosis; Cells, Cultured; Chemokine CCL2; Diosgenin; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Human Umbilical Vein Endothelial Cells; Humans; Macrophages, Peritoneal; Malondialdehyde; Mice, Knockout, ApoE; Molecular Docking Simulation; Nitric Oxide Synthase Type III; Postmenopause; Tumor Necrosis Factor-alpha

2020
Inhibitory effects of Dioscin on atherosclerosis and foam cell formation in hyperlipidemia rats.
    Inflammopharmacology, 2017, Volume: 25, Issue:6

    Topics: Animals; Atherosclerosis; Cells, Cultured; Cholesterol; Diosgenin; Foam Cells; Hyperlipidemias; Interleukin-1beta; Interleukin-6; Lipoproteins, LDL; Macrophages; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Scavenger Receptors, Class E

2017
Inhibition of nuclear translocation of notch intracellular domain (NICD) by diosgenin prevented atherosclerotic disease progression.
    Biochimie, 2018, Volume: 148

    Topics: Active Transport, Cell Nucleus; Animals; Aorta; Atherosclerosis; Cell Differentiation; Cell Line; Cell Nucleus; Diosgenin; Disease Progression; Macrophages; Male; Protein Domains; Rats; Rats, Wistar; Receptors, Notch; RNA, Messenger; Signal Transduction

2018
Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1.
    Atherosclerosis, 2015, Volume: 240, Issue:1

    Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; Cell Line; Cholesterol; Diosgenin; Disease Models, Animal; Dose-Response Relationship, Drug; Foam Cells; Gene Expression Regulation; Humans; Hypolipidemic Agents; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Transfection

2015
Influence of different particle processing on hypocholesterolemic and antiatherogenic activities of yam (Dioscorea pseudojaponica) in cholesterol-fed rabbit model.
    Journal of the science of food and agriculture, 2013, Volume: 93, Issue:6

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anticholesteremic Agents; Aorta; Atherosclerosis; Cardiovascular Agents; Cholesterol, Dietary; Diet; Dioscorea; Diosgenin; Disease Models, Animal; Fatty Liver; Food Handling; Functional Food; Hypercholesterolemia; Liver; Male; Nanoparticles; Particle Size; Plant Preparations; Plant Tubers; Rabbits

2013