Compounds > diosgenin
Page last updated: 2024-08-26

diosgenin and Adenocarcinoma of Lung

diosgenin has been researched along with Adenocarcinoma of Lung in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chen, W; Du, B; He, Y; Jin, H; Mao, W; Tan, Y; Wu, S; Yin, H; Zhang, R; Zhao, T1
Chen, Y; Deng, H; Lou, W; Wang, J; Wu, T; Zhu, KY1
Choi, KC; Kim, H; Kim, MK; Kim, YJ; Ko, H; Lee, IH; Lee, KH; Lim, WC1
Chen, CY; Lee, H; Wang, L; Wang, YC; Wu, DW; Wu, TC1
Han, X; Liu, K; Peng, J; Qi, Y; Sun, H; Wei, Y; Xu, L; Xu, Y; Yin, L1
Feng, J; Jiang, H; Ma, S; Su, D; Zhao, P; Zhu, X1
Du, LW; Feng, JG; Jiang, H; Li, JH; Ma, SL; Song, SC; Zhao, PJ; Zhou, GH; Zhu, XH1

Other Studies

7 other study(ies) available for diosgenin and Adenocarcinoma of Lung

ArticleYear
Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diosgenin; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2020
Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition.
    Biological & pharmaceutical bulletin, 2017, Aug-01, Volume: 40, Issue:8

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diosgenin; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Humans; Interleukin-6; Lung Neoplasms; Melanthiaceae; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase Inhibitors; Rhizome; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2017
Dioscin suppresses TGF-β1-induced epithelial-mesenchymal transition and suppresses A549 lung cancer migration and invasion.
    Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship; Transforming Growth Factor beta1

2017
Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression.
    International journal of biological sciences, 2018, Volume: 14, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Apoptosis; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Diosgenin; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Mutation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Reactive Oxygen Species

2018
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Large Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosol; Diosgenin; DNA Damage; Humans; Inhibitory Concentration 50; Lung Neoplasms; Microscopy, Electron, Transmission; Mitochondria; Protein Transport; S Phase; Signal Transduction; Small Cell Lung Carcinoma

2013
Inhibition of cell proliferation by mild hyperthermia at 43˚C with Paris Saponin I in the lung adenocarcinoma cell line PC-9.
    Molecular medicine reports, 2015, Volume: 11, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Diosgenin; Hot Temperature; Humans; Hyperthermia, Induced; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Saponins

2015
Paris Saponins enhance radiosensitivity in a gefitinib-resistant lung adenocarcinoma cell line by inducing apoptosis and G2/M cell cycle phase arrest.
    Molecular medicine reports, 2016, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diosgenin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Gefitinib; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Radiation Tolerance; Radiation-Sensitizing Agents; Saponins

2016