Page last updated: 2024-08-26

diosgenin and Acute Confusional Senile Dementia

diosgenin has been researched along with Acute Confusional Senile Dementia in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (46.15)24.3611
2020's7 (53.85)2.80

Authors

AuthorsStudies
Chojnacki, JE; Liu, K; Saathoff, JM; Zhang, S1
Huang, J; Huang, Y; Li, J; Ma, L; Su, L; Tang, Y; Wang, R; Wu, YH; Yang, GX; Zhang, L; Zheng, LL; Zhou, LC1
Huang, W; Huang, Y; Ma, L; Wang, R; Yang, G1
Azuma, K; Gao, X; Liu, X; Saido, TC; Saito, T; Wang, KY; Wang, X; Zhang, JH; Zhou, Q1
Antony, J; Dhanabal, S; Ponnusankar, S; Som, S1
Tohda, C; Yang, X1
Han, K; Jia, N; Sun, C; Wang, C; Zhang, Z1
Chen, C; Chen, H; Fan, J; Fan, X; Gong, Y; Huang, K; Huang, X; Jiang, H; Jiang, N; Liu, R; Liu, X; Ma, J; Ma, S; Shentu, Y; Song, S; Wang, X; Yang, D; Ye, S; Zhao, Z; Zheng, C; Zhou, Y1
Goto, Y; Lee, YA; Nemere, I; Tohda, C1
Tohda, C1
Greeson, J; Lecanu, L; McCourty, A; Papadopoulos, V; Rammouz, G; Sidahmed, EK1
Lecanu, L; Papadopoulos, V1
Kuboyama, T; Nemere, I; Tohda, C; Umezaki, M; Urano, T1

Reviews

2 review(s) available for diosgenin and Acute Confusional Senile Dementia

ArticleYear
New Age Therapy for Alzheimer's Disease by Neuronal Network Reconstruction.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Atrophy; Diosgenin; Humans; Medicine, Traditional; Neurons; Saponins; Withanolides

2016
Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties.
    Journal of neuroendocrinology, 2012, Volume: 24, Issue:1

    Topics: Alzheimer Disease; Animals; Brain; Caproates; Diosgenin; Drug Discovery; Humans; Hydroxycholesterols; Neurons; Rats; Spirostans

2012

Other Studies

11 other study(ies) available for diosgenin and Acute Confusional Senile Dementia

ArticleYear
Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2015, Nov-15, Volume: 23, Issue:22

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Cell Line, Tumor; Cell Survival; Curcumin; Diosgenin; Drug Design; Humans; Ligands; Neuroprotective Agents; Reactive Oxygen Species; Thiazoles

2015
Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents.
    European journal of medicinal chemistry, 2020, Feb-01, Volume: 187

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Carbamates; Cell Line, Tumor; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Galactose; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Molecular Structure; Neuroprotective Agents; Oxidative Stress; Protein Aggregates; Structure-Activity Relationship

2020
Design and synthesis of novel diosgenin-triazole hybrids targeting inflammation as potential neuroprotective agents.
    Bioorganic & medicinal chemistry letters, 2021, 07-01, Volume: 43

    Topics: Alzheimer Disease; Animals; Cell Line; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Inflammation; Lipopolysaccharides; Molecular Conformation; Neuroprotective Agents; Nitric Oxide; Rats; Structure-Activity Relationship; Triazoles

2021
Microglia-Based Sex-Biased Neuropathology in Early-Stage Alzheimer's Disease Model Mice and the Potential Pharmacologic Efficacy of Dioscin.
    Cells, 2021, 11-22, Volume: 10, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; beta Catenin; Body Weight; Brain; Cytokines; Diosgenin; Disease Models, Animal; Female; Male; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Models, Biological; NF-kappa B; Sex Characteristics; Signal Transduction; Synapses

2021
Neuroprotective role of Diosgenin, a NGF stimulator, against Aβ (1-42) induced neurotoxicity in animal model of Alzheimer's disease.
    Metabolic brain disease, 2022, Volume: 37, Issue:2

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Diosgenin; Disease Models, Animal; Hippocampus; Maze Learning; Nerve Growth Factor; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar

2022
Diosgenin restores memory function via SPARC-driven axonal growth from the hippocampus to the PFC in Alzheimer's disease model mice.
    Molecular psychiatry, 2023, Volume: 28, Issue:6

    Topics: Alzheimer Disease; Animals; Axons; Diosgenin; Disease Models, Animal; Hippocampus; Mice; Mice, Transgenic; Osteonectin

2023
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
    Chemical & pharmaceutical bulletin, 2020, Volume: 68, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Autophagy; Beclin-1; Cell Line; Diosgenin; Down-Regulation; Humans; Neurons; Peptide Fragments; Protective Agents; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Sirtuin 3; Up-Regulation

2020
Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:12

    Topics: Alzheimer Disease; Animals; Autoantigens; Cell Line; Cognitive Dysfunction; Diosgenin; Enzyme Inhibitors; HEK293 Cells; Humans; Male; Membrane Proteins; Mice; Mice, Transgenic; Neurons; Protein Phosphatase 2; Signal Transduction

2020
Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D₃-MARRS.
    Scientific reports, 2013, Dec-02, Volume: 3

    Topics: Alzheimer Disease; Animals; Axons; Cells, Cultured; Cerebral Cortex; Cognition; Diosgenin; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurons; Nootropic Agents; Protein Disulfide-Isomerases

2013
Caprospinol reduces amyloid deposits and improves cognitive function in a rat model of Alzheimer's disease.
    Neuroscience, 2010, Jan-20, Volume: 165, Issue:2

    Topics: Alzheimer Disease; Animals; Astrocytes; Caproates; Cognition Disorders; Diosgenin; Disease Models, Animal; Gliosis; Hippocampus; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Neuroprotective Agents; Phosphorylation; Plaque, Amyloid; Prosencephalon; Rats; Rats, Long-Evans; Spirostans; tau Proteins

2010
Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice.
    Scientific reports, 2012, Volume: 2

    Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Axons; Cerebellar Cortex; Diosgenin; Disease Models, Animal; Female; Gene Knockdown Techniques; Male; Memory Disorders; Mice; Molecular Docking Simulation; Neurons; Plaque, Amyloid; Presynaptic Terminals; Protein Conformation; Protein Disulfide-Isomerases; Protein Kinase Inhibitors

2012