Page last updated: 2024-09-03

dioscin and Lung Neoplasms

dioscin has been researched along with Lung Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Gao, W; Jing, S; Li, X; Man, S; Sun, J; Wang, Y; Zhao, C1
Choi, KC; Kim, H; Kim, MK; Kim, YJ; Ko, H; Lee, IH; Lee, KH; Lim, WC1
Du, G; Gao, F; Gu, W; Kui, F; Li, W; Liu, Z; Lu, L; Niu, Y; Xi, P; Zhang, Y1
Cai, FY; Fu, M; He, SY; Jing, M; Ju, RJ; Kong, L; Li, XT; Liu, JJ; Liu, XZ; Yao, XM; Zhang, L1
Chen, W; Du, B; He, Y; Jin, H; Mao, W; Tan, Y; Wu, S; Yin, H; Zhang, R; Zhao, T1
Chen, CY; Lee, H; Wang, L; Wang, YC; Wu, DW; Wu, TC1
Fan, L; Fu, M; Li, G; Li, J; Li, X; Liu, J; Pan, W; Wang, X; Wang, Y; Yang, Y; Yu, Y1
Chiou, HL; Hsieh, MJ; Hsieh, YS; Tsai, TL; Wang, CJ1
Han, X; Liu, K; Peng, J; Qi, Y; Sun, H; Wei, Y; Xu, L; Xu, Y; Yin, L1

Other Studies

9 other study(ies) available for dioscin and Lung Neoplasms

ArticleYear
Novel phenanthrene and isocoumarin from the rhizomes of Dioscorea nipponica Makino subsp. rosthornii (Prain et Burkill) C. T. Ting (Dioscoreaceae).
    Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dioscorea; Humans; Isocoumarins; Lung; Lung Neoplasms; Phenanthrenes; Plant Extracts; Rhizome

2017
Dioscin suppresses TGF-β1-induced epithelial-mesenchymal transition and suppresses A549 lung cancer migration and invasion.
    Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship; Transforming Growth Factor beta1

2017
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
    Journal of ethnopharmacology, 2022, Jun-28, Volume: 292

    Topics: Animals; Diosgenin; Drugs, Chinese Herbal; Lung Neoplasms; Matrix Metalloproteinase 2; Mice; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt

2022
RPV-modified epirubicin and dioscin co-delivery liposomes suppress non-small cell lung cancer growth by limiting nutrition supply.
    Cancer science, 2020, Volume: 111, Issue:2

    Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell-Penetrating Peptides; Diosgenin; Epirubicin; Gene Expression Regulation, Neoplastic; Humans; Liposomes; Lung Neoplasms; Male; Mice; Neovascularization, Pathologic; Rats; Xenograft Model Antitumor Assays

2020
Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diosgenin; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2020
Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression.
    International journal of biological sciences, 2018, Volume: 14, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Apoptosis; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Diosgenin; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Mutation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Reactive Oxygen Species

2018
Inhibition of tumor metastasis by targeted daunorubicin and dioscin codelivery liposomes modified with PFV for the treatment of non-small-cell lung cancer.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: A549 Cells; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Daunorubicin; Diosgenin; Drug Delivery Systems; Female; Humans; Liposomes; Lung Neoplasms; Matrix Metalloproteinase 2; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Oligopeptides; Particle Size; Static Electricity; Wound Healing

2019
Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines.
    Archives of toxicology, 2013, Volume: 87, Issue:11

    Topics: Annexin A5; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Diosgenin; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Indoles; Lung Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Oncogene Protein v-akt; Organelles; Phosphatidylinositol 3-Kinases; Signal Transduction

2013
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Large Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosol; Diosgenin; DNA Damage; Humans; Inhibitory Concentration 50; Lung Neoplasms; Microscopy, Electron, Transmission; Mitochondria; Protein Transport; S Phase; Signal Transduction; Small Cell Lung Carcinoma

2013