Page last updated: 2024-09-03

dioscin and Innate Inflammatory Response

dioscin has been researched along with Innate Inflammatory Response in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (53.85)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Guan, T; Hu, M; Huang, S; Jin, S; Liu, X; Liu, Y; Wang, S1
Gao, M; Qi, Y; Wang, J; Xu, L; Yin, L; Zhang, Z; Zhao, X1
Deng, S; Jin, S; Li, D; Li, J; Liu, X; Liu, Y; Zhu, T1
Luo, H; Lv, Z; Wang, B; Wang, X; Wang, Z; Wu, X; Xun, J; Yang, L; Yu, X; Zhang, A; Zhang, L; Zhang, Q; Zhou, S1
Jin, Y; Liu, K; Ma, X; Sun, H; Wang, C; Wang, J; Xie, T; Yang, Q1
Li, Y; Wang, M; Yang, T1
Han, J; Jiang, D; Li, F; Li, W; Shi, G; Xie, Y1
Su, F; Tang, S; Zhu, S1
Han, X; Liu, K; Ma, X; Peng, J; Qi, Y; Qiao, Y; Tang, Z; Tao, X; Xu, L; Xu, Y; Yin, L1
Cao, F; Cao, YK; Li, CW; Li, Y; Wang, YB; Wu, Q; Xu, B; Yang, B; Zhang, J; Zhao, H1
Liu, M; Lu, J; Sun, H; Wang, S; Zhang, T1
Han, X; Lin, Y; Peng, J; Qi, Y; Tao, X; Wan, X; Xu, L; Xu, Y; Yin, L1
Han, X; Lin, Y; Liu, K; Liu, M; Peng, J; Qi, Y; Sun, H; Xu, L; Xu, Y; Yao, J; Yin, L; Zhao, Y1

Other Studies

13 other study(ies) available for dioscin and Innate Inflammatory Response

ArticleYear
Dioscin Alleviates Cisplatin-Induced Mucositis in Rats by Modulating Gut Microbiota, Enhancing Intestinal Barrier Function and Attenuating TLR4/NF-κB Signaling Cascade.
    International journal of molecular sciences, 2022, Apr-17, Volume: 23, Issue:8

    Topics: Animals; Cisplatin; Diosgenin; Gastrointestinal Microbiome; Humans; Inflammation; Mucositis; Myeloid Differentiation Factor 88; NF-kappa B; Rats; Signal Transduction; Toll-Like Receptor 4

2022
Dioscin alleviates myocardial infarction injury via regulating BMP4/NOX1-mediated oxidative stress and inflammation.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 103

    Topics: Animals; Bone Morphogenetic Protein 4; Diosgenin; Hypoxia; Inflammation; Interleukin-6; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C57BL; Myocardial Infarction; NADPH Oxidase 1; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2022
Dioscin ameliorates cisplatin-induced intestinal toxicity by mitigating oxidative stress and inflammation.
    International immunopharmacology, 2022, Volume: 111

    Topics: Animals; Antioxidants; Cisplatin; Diosgenin; Hydrogen Peroxide; Inflammation; NF-E2-Related Factor 2; Oxidative Stress; Rats

2022
Dioscin modulates macrophages polarization and MDSCs differentiation to inhibit tumorigenesis of colitis-associated colorectal cancer.
    International immunopharmacology, 2023, Volume: 117

    Topics: Animals; Carcinogenesis; Cell Differentiation; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells

2023
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
    Pharmacological research, 2019, Volume: 148

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Cells, Cultured; Diosgenin; Endothelial Cells; Estrogen Receptor alpha; Female; Humans; Inflammation; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Ovariectomy; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Plant Extracts; Postmenopause; Receptors, LDL; Signal Transduction

2019
Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK.
    Molecular medicine reports, 2020, Volume: 21, Issue:1

    Topics: Adult; Atherosclerosis; CD36 Antigens; Dendritic Cells; Diosgenin; Female; Gene Expression Regulation; Glucose; Humans; Inflammation; Interleukin-10; Interleukin-12; Interleukin-6; Lipoproteins, LDL; Male; p38 Mitogen-Activated Protein Kinases; Scavenger Receptors, Class A; Scavenger Receptors, Class E

2020
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.
    Journal of natural medicines, 2021, Volume: 75, Issue:1

    Topics: Animals; Arthritis, Gouty; Diosgenin; Humans; Inflammasomes; Inflammation; Male; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Toll-Like Receptor 4; Uric Acid

2021
Dioscin inhibits ischemic stroke‑induced inflammation through inhibition of the TLR4/MyD88/NF‑κB signaling pathway in a rat model.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Animals; Brain Ischemia; Diosgenin; HMGB1 Protein; Humans; Inflammation; Interleukin-1 Receptor-Associated Kinases; Myeloid Differentiation Factor 88; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Stroke; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Transforming Growth Factor beta1

2018
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
    Toxicology letters, 2018, Mar-01, Volume: 284

    Topics: Animals; Diosgenin; Disease Models, Animal; Fibrosis; Fructose; Inflammation; Kidney; Lipid Metabolism; Male; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Renal Insufficiency, Chronic

2018
Dioscin protects against coronary heart disease by reducing oxidative stress and inflammation via Sirt1/Nrf2 and p38 MAPK pathways.
    Molecular medicine reports, 2018, Volume: 18, Issue:1

    Topics: Animals; Coronary Disease; Diosgenin; Inflammation; Male; MAP Kinase Signaling System; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Sirtuin 1; Swine; Swine, Miniature

2018
Protective effects of dioscin against cartilage destruction in a monosodium iodoacetate (MIA)-indcued osteoarthritis rat model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Apoptosis; beta Catenin; Cartilage, Articular; Diosgenin; Disease Models, Animal; Extracellular Matrix; Inflammation; Iodoacetates; Male; Osteoarthritis; Oxidative Stress; PPAR gamma; Protective Agents; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway

2018
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
    Transplantation, 2014, Sep-27, Volume: 98, Issue:6

    Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Diosgenin; Dose-Response Relationship, Drug; Inflammation; Liver; Male; Nitrogen; Oxidative Stress; Phosphorylation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Warm Ischemia

2014
Potent effects of dioscin against obesity in mice.
    Scientific reports, 2015, Jan-22, Volume: 5

    Topics: Animals; Autophagy; Blood Glucose; Body Weight; Cholesterol; Diet, High-Fat; Diosgenin; Energy Metabolism; Fatty Acids; Glucose Tolerance Test; Inflammation; Liver; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidative Stress; Phosphorylation; Signal Transduction; Triglycerides

2015