dioscin has been researched along with Disease Models, Animal in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 11 (45.83) | 2.80 |
| Authors | Studies |
|---|---|
| Chai, H; Cordell, GA; Farnsworth, NR; Hollingshead, MG; Kardono, LB; Kinghorn, AD; Lantvit, D; Lee, IS; Mayo, JG; Mi, Q; Ngassapa, O; Peraza-Sánchez, S; Pezzuto, JM; Reyes-Lim, E; Riswan, S; Zhao, W | 1 |
| Lu, Z; Peng, JY; Wang, J; Yao, Y | 1 |
| Azuma, K; Gao, X; Liu, X; Saido, TC; Saito, T; Wang, KY; Wang, X; Zhang, JH; Zhou, Q | 1 |
| Li, H; Li, S; Liu, J; Nie, B; Pang, B; Qu, S; Xu, J; Yang, M; Zhang, K | 1 |
| Qi, Y; Shang, Q; Shang, W; Zeng, J; Zhu, L | 1 |
| Fan, L; Li, J; Liu, B; Ni, R; Song, Y; Wang, A; Wang, H; Zhang, L | 1 |
| Luo, H; Lv, Z; Wang, B; Wang, X; Wang, Z; Wu, X; Xun, J; Yang, L; Yu, X; Zhang, A; Zhang, L; Zhang, Q; Zhou, S | 1 |
| Choi, SS; de Guzman, ACV; Purevdulam, B; Razzak, MA | 1 |
| Han, X; Peng, JY; Qi, Y; Song, S; Sun, C; Xu, L; Xu, Y; Yang, Y; Yin, L; Zhao, Y; Zhu, M | 1 |
| He, C; Kong, C; Li, R; Lu, Q; Lyu, D | 1 |
| Cai, J; Cao, Y; Dong, X; Fan, P; Liu, J; Liu, X; Zhang, N; Zhu, K | 1 |
| Huang, BY; Mai, CT; Wang, CL; Wang, QM; Wang, TT; Wu, MM; Zhang, XJ | 1 |
| Han, X; Liu, K; Ma, X; Peng, J; Qi, Y; Qiao, Y; Tang, Z; Tao, X; Xu, L; Xu, Y; Yin, L | 1 |
| Chen, Q; Jin, L; Li, J; Liu, J; Wang, T; Wang, W; Yu, H; Zhang, Y | 1 |
| Liu, M; Lu, J; Sun, H; Wang, S; Zhang, T | 1 |
| Cheng, J; Hao, Q; Sun, C; Xue, Y; Zhang, J; Zou, Q | 1 |
| Huang, T; Sun, L; Wei, Q; Xiao, X; Zhang, Z; Zhu, T | 1 |
| Cao, YJ; Hou, L; Li, XS; Liu, B; Qi, Y; Sun, YM; Wan, CP; Wen, WB; Wu, J; Xu, Y; Zhang, Y; Zheng, X | 1 |
| Han, X; Peng, J; Qi, Y; Xu, L; Xu, T; Xu, Y; Yin, L; Zheng, L | 1 |
| An, G; Feng, G; Guo, Y; Liang, X; Song, H; Wang, M; Xing, E; Zhao, X | 1 |
| Du, B; Li, B; Liu, X; Tan, Y; Wu, Y; Xiao, J; Zhang, G | 1 |
| Fan, MJ; Hsieh, WT; Liu, FC; Pan, CH; Sheu, MJ; Tsai, CH; Wu, CH | 1 |
| Du, Q; Li, B; Liu, Z; Wang, A; Wang, F; Wang, Y; Wang, Z | 1 |
| Squibb, RE; Squibb, RL | 1 |
24 other study(ies) available for dioscin and Disease Models, Animal
| Article | Year |
|---|---|
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
Topics: Animals; Biological Factors; Colonic Neoplasms; Diosgenin; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 3-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; KB Cells; Leukemia P388; Male; Melanoma; Mice; Molecular Structure; Naphthoquinones; Ovarian Neoplasms; Paclitaxel; Polymers; Prostatic Neoplasms; Triterpenes; Tumor Cells, Cultured | 2002 |
Dioscin ameliorates diabetes cognitive dysfunction via adjusting P2X7R/NLRP3 signal.
Topics: Animals; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Diosgenin; Disease Models, Animal; Inflammasomes; Interleukin-1beta; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Receptors, Purinergic P2X7; Signal Transduction | 2021 |
Microglia-Based Sex-Biased Neuropathology in Early-Stage Alzheimer's Disease Model Mice and the Potential Pharmacologic Efficacy of Dioscin.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; beta Catenin; Body Weight; Brain; Cytokines; Diosgenin; Disease Models, Animal; Female; Male; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Models, Biological; NF-kappa B; Sex Characteristics; Signal Transduction; Synapses | 2021 |
Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Colitis, Ulcerative; Colon; Dextran Sulfate; Diosgenin; Disease Models, Animal; Mice; TOR Serine-Threonine Kinases | 2022 |
Dioscin exhibits protective effects on in vivo and in vitro asthma models via suppressing TGF-β1/Smad2/3 and AKT pathways.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Collagen; Diosgenin; Disease Models, Animal; Humans; Hyperplasia; Immunoglobulin E; Immunoglobulin G; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Proto-Oncogene Proteins c-akt; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2022 |
Dioscin Regulating Bone Marrow Apoptosis in Aplastic Anemia.
Topics: Anemia, Aplastic; Animals; Apoptosis; Bone Marrow; Diosgenin; Disease Models, Animal; Mice | 2022 |
Dioscin modulates macrophages polarization and MDSCs differentiation to inhibit tumorigenesis of colitis-associated colorectal cancer.
Topics: Animals; Carcinogenesis; Cell Differentiation; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells | 2023 |
Anti-Parkinson's Disease Function of Dioscin-Zein-Carboxymethyl Cellulose Nanocomplex in Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Carboxymethylcellulose Sodium; Diosgenin; Disease Models, Animal; Parkinson Disease; Zein | 2020 |
Protective effects of dioscin on vascular remodeling in pulmonary arterial hypertension via adjusting GRB2/ERK/PI3K-AKT signal.
Topics: Animals; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Diosgenin; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; GRB2 Adaptor Protein; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2021 |
Dioscin elevates lncRNA MANTIS in therapeutic angiogenesis for heart diseases.
Topics: Animals; Diosgenin; Disease Models, Animal; Heart Diseases; Humans; Male; Mice; Neovascularization, Physiologic; RNA, Long Noncoding | 2021 |
Dioscin prevents DSS-induced colitis in mice with enhancing intestinal barrier function and reducing colon inflammation.
Topics: Animals; Colitis, Ulcerative; Colon; Dextran Sulfate; Diosgenin; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Male; Mice | 2021 |
Dioscin ameliorates murine ulcerative colitis by regulating macrophage polarization.
Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Diosgenin; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred BALB C; PPAR gamma; RAW 264.7 Cells | 2021 |
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Topics: Animals; Diosgenin; Disease Models, Animal; Fibrosis; Fructose; Inflammation; Kidney; Lipid Metabolism; Male; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Renal Insufficiency, Chronic | 2018 |
Effect and mechanism of dioscin from Dioscorea spongiosa on uric acid excretion in animal model of hyperuricemia.
Topics: Adenine; Animals; Biomarkers; Creatinine; Dioscorea; Diosgenin; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Transport Proteins, Facilitative; HCT116 Cells; Humans; Hyperuricemia; Intestinal Elimination; Intestinal Mucosa; Intestines; Male; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Cation Transport Proteins; Oxonic Acid; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Renal Elimination; Spirostans; Time Factors; Uric Acid; Uricosuric Agents | 2018 |
Protective effects of dioscin against cartilage destruction in a monosodium iodoacetate (MIA)-indcued osteoarthritis rat model.
Topics: Animals; Apoptosis; beta Catenin; Cartilage, Articular; Diosgenin; Disease Models, Animal; Extracellular Matrix; Inflammation; Iodoacetates; Male; Osteoarthritis; Oxidative Stress; PPAR gamma; Protective Agents; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway | 2018 |
The Protective Effects of Preconditioning With Dioscin on Myocardial Ischemia/Reperfusion-Induced Ventricular Arrhythmias by Increasing Connexin 43 Expression in Rats.
Topics: Animals; Arrhythmias, Cardiac; Biomarkers; Connexin 43; Creatine Kinase, MB Form; Diosgenin; Disease Models, Animal; Heart Rate; Male; Myocardial Reperfusion Injury; Phosphorylation; Protective Agents; Rats, Sprague-Dawley; Tachycardia, Ventricular; Troponin I; Up-Regulation; Ventricular Fibrillation; Ventricular Premature Complexes | 2019 |
Dioscin Attenuates Myocardial Damages in Diabetic Rats maybe by Regulating NO-sGC-cGMP-PKG Pathway.
Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Diosgenin; Disease Models, Animal; Fibrosis; Guanylate Cyclase; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Dioscin, a Steroidal Saponin Isolated from Dioscorea nipponica, Attenuates Collagen-Induced Arthritis by Inhibiting Th17 Cell Response.
Topics: Animals; Arthritis; Cell Differentiation; Cells, Cultured; Collagen; Cytokines; Dioscorea; Diosgenin; Disease Models, Animal; Female; Male; Mice, Inbred BALB C; Mice, Inbred DBA; Phytotherapy; Th17 Cells | 2019 |
Protective effects of dioscin against alcohol-induced liver injury.
Topics: Animals; Cytochrome P-450 CYP2E1; Diosgenin; Disease Models, Animal; Ethanol; Fatty Acids; Fatty Liver, Alcoholic; Liver; Liver Diseases, Alcoholic; Male; Mice, Inbred C57BL; Protective Agents; Rats; Rats, Wistar; Toxicity Tests, Acute; Toxicity Tests, Chronic | 2014 |
Therapeutic effect of dioscin on collagen-induced arthritis through reduction of Th1/Th2.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Collagen Type II; Dioscorea; Diosgenin; Disease Models, Animal; Diterpenes; Epoxy Compounds; GATA3 Transcription Factor; Humans; Male; Mice; Mice, Inbred DBA; Phenanthrenes; STAT Transcription Factors; Synovial Membrane; Th1 Cells; Th1-Th2 Balance; Th2 Cells | 2016 |
Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication.
Topics: Animals; Antiviral Agents; Bystander Effect; Cell Communication; Cell Survival; Connexin 26; Connexin 43; Connexins; Diosgenin; Disease Models, Animal; Drug Synergism; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Melanoma, Experimental; Mice; Mutation; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured | 2017 |
Influence of different particle processing on hypocholesterolemic and antiatherogenic activities of yam (Dioscorea pseudojaponica) in cholesterol-fed rabbit model.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anticholesteremic Agents; Aorta; Atherosclerosis; Cardiovascular Agents; Cholesterol, Dietary; Diet; Dioscorea; Diosgenin; Disease Models, Animal; Fatty Liver; Food Handling; Functional Food; Hypercholesterolemia; Liver; Male; Nanoparticles; Particle Size; Plant Preparations; Plant Tubers; Rabbits | 2013 |
Microarray analysis of gene expression on herbal glycoside recipes improving deficient ability of spatial learning memory in ischemic mice.
Topics: 14-3-3 Proteins; Blotting, Western; Brain Ischemia; Diosgenin; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; Flavonoids; Gene Expression; Glycosides; Hippocampus; Maze Learning; Memory Disorders; Oligonucleotide Array Sequence Analysis; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine 3-Monooxygenase | 2004 |
Effect of food toxicants on voluntary wheel running in rats.
Topics: Animals; Cadmium; Diosgenin; Disease Models, Animal; Dose-Response Relationship, Drug; Food Deprivation; Glycosides; Iron; Iron Deficiencies; Liver; Male; Motor Activity; Rats; Sapogenins; Testis | 1979 |