Compounds > dioscin
Page last updated: 2024-09-03

dioscin and Chemical and Drug Induced Liver Injury

dioscin has been researched along with Chemical and Drug Induced Liver Injury in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Li, N; Liu, L; Wang, Y; Yue, X; Zhang, Y1
Han, X; Li, H; Liu, K; Peng, J; Qi, Y; Xu, L; Xu, Y; Yin, L; Zheng, L1
Gao, Y; Liang, QD; Ma, ZC; Tan, HL; Tang, XL; Wang, YG; Xiao, CR; Zhang, YX; Zhao, YH1
Han, X; Hu, C; Peng, J; Qi, Y; Tao, X; Wang, C; Xu, L; Xu, Y; Yao, H; Yin, L; Zhao, Y1
Han, X; Peng, J; Tao, X; Wang, C; Xu, L; Xu, Y; Yin, L; Zhang, W; Zheng, L1
Lu, B; Peng, J; Xu, L; Yin, L1
Cong, X; Li, H; Lu, B; Peng, J; Xu, L; Xu, Y; Yin, L1
Cong, X; Peng, J; Xu, L; Yin, L; Zhao, X; Zheng, L1

Other Studies

8 other study(ies) available for dioscin and Chemical and Drug Induced Liver Injury

ArticleYear
3D scaffold fabricated with composite material for cell culture and its derived platform for safety evaluation of drugs.
    Toxicology, 2022, 01-30, Volume: 466

    Topics: Acetaminophen; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Chemical and Drug Induced Liver Injury; Composite Resins; Cytochrome P-450 Enzyme System; Diosgenin; Drug Evaluation, Preclinical; Glucose; Hep G2 Cells; Humans; Pharmaceutical Preparations; Tissue Scaffolds

2022
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: AMP-Activated Protein Kinases; Animals; Chemical and Drug Induced Liver Injury; Diosgenin; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thioacetamide

2018
[Preliminary study on hepatotoxicity induced by dioscin and its possible mechanism].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:14

    Topics: Cell Survival; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; Diosgenin; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; RNA, Messenger

2015
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
    International immunopharmacology, 2016, Volume: 36

    Topics: Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Cytokines; Dioscorea; Diosgenin; Hep G2 Cells; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; Toll-Like Receptor 4

2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
    Environmental toxicology and pharmacology, 2016, Volume: 45

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cytokines; Dimethylnitrosamine; Dioscorea; Diosgenin; Interferon-Stimulated Gene Factor 3, gamma Subunit; Male; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Toll-Like Receptor 4

2016
Application of proteomic and bioinformatic techniques for studying the hepatoprotective effect of dioscin against CClâ‚„-induced liver damage in mice.
    Planta medica, 2011, Volume: 77, Issue:5

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Computational Biology; Diosgenin; Endoplasmic Reticulum Chaperone BiP; Liver; Male; Mice; Necrosis; Protective Agents; Protein Interaction Mapping; Proteomics; Silymarin

2011
Mechanism investigation of dioscin against CCl4-induced acute liver damage in mice.
    Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:2

    Topics: Animals; Carbon Tetrachloride; Caspase 3; Caspase 8; Chemical and Drug Induced Liver Injury; Diosgenin; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Protective Agents; Superoxide Dismutase

2012
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.
    Toxicology letters, 2012, Oct-02, Volume: 214, Issue:1

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Biological Products; Chemical and Drug Induced Liver Injury; Comet Assay; Diosgenin; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Male; Mice; Mitochondria; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012