dioncophylline-a and Neoplasms

dioncophylline-a has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for dioncophylline-a and Neoplasms

Article	Year
New naphthalene derivatives and isoquinoline alkaloids from Ancistrocladus cochinchinensis with their anti-proliferative activity on human cancer cells. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Five new compounds, named ancistronaphtosides A and B (1 and 2), anciscochine (3), anciscochine 6-O-β-d-glucopyranoside (4), and 4'-methoxy-5-epi-ancistecrorine A1 (5), together with tortoside A (6) and 4-hydroxy-2-methoxyphenyl-6-O-syringoyl-β-d-glucopyranoside (7) were isolated from the methanolic extract of Ancistrocladus cochinchinensis. Their chemical structures were established using HR-ESI-MS, NMR spectroscopic, and chiroptical methods. Compound 5 significantly exhibited anti-proliferation against HL-60, LU-1, and SK-MEL-2 cells with IC50 values of 5.0±1.2, 6.5±1.6, and 6.8±2.0μg/mL, respectively. Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; HL-60 Cells; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Magnoliopsida; Molecular Conformation; Naphthalenes; Neoplasms; Plant Extracts; Spectrometry, Mass, Electrospray Ionization	2016

Article

Year

New naphthalene derivatives and isoquinoline alkaloids from Ancistrocladus cochinchinensis with their anti-proliferative activity on human cancer cells.

Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

Five new compounds, named ancistronaphtosides A and B (1 and 2), anciscochine (3), anciscochine 6-O-β-d-glucopyranoside (4), and 4'-methoxy-5-epi-ancistecrorine A1 (5), together with tortoside A (6) and 4-hydroxy-2-methoxyphenyl-6-O-syringoyl-β-d-glucopyranoside (7) were isolated from the methanolic extract of Ancistrocladus cochinchinensis. Their chemical structures were established using HR-ESI-MS, NMR spectroscopic, and chiroptical methods. Compound 5 significantly exhibited anti-proliferation against HL-60, LU-1, and SK-MEL-2 cells with IC50 values of 5.0±1.2, 6.5±1.6, and 6.8±2.0μg/mL, respectively.

Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; HL-60 Cells; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Magnoliopsida; Molecular Conformation; Naphthalenes; Neoplasms; Plant Extracts; Spectrometry, Mass, Electrospray Ionization

2016