dinitrochlorobenzene has been researched along with Vitiligo in 6 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty patients with vitiligo (ten of the segmental type and 20 of the generalized type) were sensitized with dinitrochlorobenzene (DNCB) in a normal skin site on the upper medial aspect of the arm." | 3.67 | Diminished contact sensitivity response in vitiliginous skin. ( Miyauchi, H; Tanaka, S; Uehara, M, 1984) |
| "We used patch testing to compare the ability to elicit contact sensitivity to dinitrochlorobenzene (DNCB) of uninvolved with vitiliginous skin of 31 patients with vitiligo." | 3.67 | Possible functional impairment of Langerhans' cells in vitiliginous skin. Reduced ability to elicit dinitrochlorobenzene contact sensitivity reaction and decreased stimulatory effect in the allogeneic mixed skin cell lymphocyte culture reaction. ( Aiba, S; Hatchome, N; Kato, T; Tagami, H; Torinuki, W, 1987) |
| "In vitiliginous patches diminished contact sensitivity reactions to dinitrochlorobenzene were noted in both patient groups, while in normal skin sites a normal delayed hypersensitivity response to the same antigen developed in the same patients." | 1.27 | Diminished contact sensitivity response in vitiliginous skin. ( Miyauchi, H; Tanaka, S; Uehara, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uehara, M | 1 |
| Miyauchi, H | 1 |
| Tanaka, S | 1 |
| Gianadda, B | 1 |
| Ortonne, JP | 1 |
| Thivolet, J | 1 |
| Haji-Abrassi, M | 1 |
| Samsoen, M | 1 |
| Grosshans, E | 1 |
| Moróc, A | 1 |
| Král, V | 1 |
| Duchková, H | 1 |
| Richter, J | 1 |
| Hatchome, N | 1 |
| Aiba, S | 1 |
| Kato, T | 1 |
| Torinuki, W | 1 |
| Tagami, H | 1 |
6 other studies available for dinitrochlorobenzene and Vitiligo
| Article | Year |
|---|---|
Diminished contact sensitivity response in vitiliginous skin.
Topics: Adolescent; Adult; Aged; Child; Dermatitis, Contact; Dinitrochlorobenzene; Female; Humans; Hypersens | 1984 |
[Treatment of vitiligo by association of DNCB-PUVA].
Topics: Adult; Dinitrochlorobenzene; Drug Therapy, Combination; Humans; Male; Nitrobenzenes; Photochemothera | 1980 |
[Vitiligo and DNCB sensitization in achromic skin].
Topics: Dinitrochlorobenzene; Humans; Nitrobenzenes; Skin Pigmentation; Skin Tests; Vitiligo | 1981 |
[Vitiligo and malignant melanoma].
Topics: BCG Vaccine; Dinitrochlorobenzene; Female; Humans; Male; Melanoma; Vitiligo | 1980 |
Possible functional impairment of Langerhans' cells in vitiliginous skin. Reduced ability to elicit dinitrochlorobenzene contact sensitivity reaction and decreased stimulatory effect in the allogeneic mixed skin cell lymphocyte culture reaction.
Topics: Antigens, Fungal; Candida albicans; Dinitrochlorobenzene; Female; Humans; Langerhans Cells; Lymphocy | 1987 |
Langerhans' cells in vitiligo.
Topics: Dermatitis, Contact; Dinitrochlorobenzene; Humans; Langerhans Cells; Vitiligo | 1987 |