dinitrochlorobenzene has been researched along with Skin Neoplasms in 71 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-nine selected patients with recurrent melanoma (37 locoregional and 22 locoregional and haematogenic) were treated with a combination of topical dinitrochlorobenzene (DNCB) and systemic dacarbazine (DTIC)." | 9.08 | Topical dinitrochlorobenzene combined with systemic dacarbazine in the treatment of recurrent melanoma. ( Hart, AA; Israels, SP; Kroon, BB; Nieweg, OE; Rümke, P; Strobbe, LJ, 1997) |
| "Eighteen patients with multiple recurrences of malignant melanoma without evident distant spread were randomly assigned to treatment with either intralesional Bacillus Calmette-Guerin (BCG) or intralesional dinitrochlorobenzene (DNCB)." | 9.04 | Intralesional treatment of recurrent metastatic cutaneous malignant melanoma: a randomized prospective study of intralesional Bacillus Calmette-Guerin versus intralesional dinitrochlorobenzene. ( Cohen, MH; Felix, EL; Herberman, RB; Jessup, JM; Weese, JL, 1978) |
| "To scrutinize published data from small mono-centric studies and case reports which implicated high response rates and promising survival times for a combination therapy consisting of epifocal dinitrochlorobenzene (DNCB) and dacarbazine (DTIC) for metastasized melanoma." | 7.74 | Chemoimmunotherapy for cutaneous melanoma with dacarbazine and epifocal contact sensitizers: results of a nationwide survey of the German Dermatologic Co-operative Oncology Group. ( Becker, JC; Beiteke, U; Bröcker, EB; Durani, B; Jünger, M; Junghans, V; Kortüm, AK; Mauch, C; Remling, R; Schadendorf, D; Schulze, HJ; Terheyden, P, 2007) |
| "35 patients with malignant melanomas in different stages were treated with dinitrochlorobenzene according to Malek-Mansour in the last three years." | 7.66 | [Treatment of malignant melanoma with dinitrochlorobenzene ointment]. ( Ehring, F; Loth, H, 1978) |
| "Distant metastases may react--but normally these metastases cannot be removed." | 5.26 | [Treatment of malignant melanoma with dinitrochlorobenzene ointment]. ( Ehring, F; Loth, H, 1978) |
| "Fifty-nine selected patients with recurrent melanoma (37 locoregional and 22 locoregional and haematogenic) were treated with a combination of topical dinitrochlorobenzene (DNCB) and systemic dacarbazine (DTIC)." | 5.08 | Topical dinitrochlorobenzene combined with systemic dacarbazine in the treatment of recurrent melanoma. ( Hart, AA; Israels, SP; Kroon, BB; Nieweg, OE; Rümke, P; Strobbe, LJ, 1997) |
| "Eighteen patients with multiple recurrences of malignant melanoma without evident distant spread were randomly assigned to treatment with either intralesional Bacillus Calmette-Guerin (BCG) or intralesional dinitrochlorobenzene (DNCB)." | 5.04 | Intralesional treatment of recurrent metastatic cutaneous malignant melanoma: a randomized prospective study of intralesional Bacillus Calmette-Guerin versus intralesional dinitrochlorobenzene. ( Cohen, MH; Felix, EL; Herberman, RB; Jessup, JM; Weese, JL, 1978) |
| "To scrutinize published data from small mono-centric studies and case reports which implicated high response rates and promising survival times for a combination therapy consisting of epifocal dinitrochlorobenzene (DNCB) and dacarbazine (DTIC) for metastasized melanoma." | 3.74 | Chemoimmunotherapy for cutaneous melanoma with dacarbazine and epifocal contact sensitizers: results of a nationwide survey of the German Dermatologic Co-operative Oncology Group. ( Becker, JC; Beiteke, U; Bröcker, EB; Durani, B; Jünger, M; Junghans, V; Kortüm, AK; Mauch, C; Remling, R; Schadendorf, D; Schulze, HJ; Terheyden, P, 2007) |
| " Obligate contact sensitizers such as diphencyprone or dinitrochlorobenzene have been used against viral and autoimmune diseases." | 3.72 | [Topical immunomodulators in dermatology]. ( Hengge, UR; Meykadeh, N, 2003) |
| "A case is presented in which a patient with Dukes C adenocarcinoma of the sigmoid colon subsequently developed a soft tissue metastasis at the site of a marked delayed type hypersensitivity response to the commonly used skin test antigen Dinitrochlorobenzene (DNCB)." | 3.66 | Inflammatory oncotaxis after testing the skin of the cancer patient. ( Shine, T; Wallack, MK, 1981) |
| "Cell-mediated immune reactivity was studied in 23 patients with mycosis fungoides and Sézary's syndrome by a semi-quantitative 2,4-dinitrochlorobenzene (DNCB) sensibilization test and the reaction to intracutaneous microbial antigens." | 3.66 | Delayed-type hypersensitivity in patients with mycosis fungoides. ( van der Harst-Oostveen, CJ; van Vloten, WA, 1978) |
| "Cell factors of nonspecific immunity were estimated in 99 patients with different stages of melanoblastoma by delayed hypersensitivity skin test to tuberculin and DNCB (2,4-dinitrochlorobenzene)." | 3.66 | [Skin reactions of delayed hypersensitivity in melanoblastoma]. ( Khachaturian, LM; Korosteleva, TA; Potapenkova, LS; Ryzhkov, VI, 1979) |
| "Report on the application of a dinitrochlorobenzene ointment of 61 postoperative melanoma patients exhibiting clinical stages I and II." | 3.66 | [Adjuvant DNCB immunotherapy in malignant melanoma]. ( Djawari, D; Weidner, F, 1979) |
| "35 patients with malignant melanomas in different stages were treated with dinitrochlorobenzene according to Malek-Mansour in the last three years." | 3.66 | [Treatment of malignant melanoma with dinitrochlorobenzene ointment]. ( Ehring, F; Loth, H, 1978) |
| " An early transient depression of two reactions in UV-irradiated mice occurred: delayed hypersensitivity to dinitrochlorobenzene measured by footpad swelling and the graft-versus-host reaction in UV-irradiated recipients measured by the use of the popliteal lymph node weight gain assay." | 3.65 | In vivo immune responses of mice during carcinogenesis by ultraviolet irradiation. ( Beard, J; Fisher, MS; Jessup, JM; Kripke, ML; Lofgreen, JS, 1977) |
| "A group of 220 patients with mycosis fungoides (MF) and other lymphomatous diseases was treated with sustained topical applications of dilute aqueous solutions of mechlorethamine hydrochloride for intervals ranging in excess of seven years." | 3.65 | Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results. ( Asbell, SO; Grekin, DA; Johnson, WC; Van Scott, EJ; Vonderheid, EC, 1977) |
| "Patients with malignant skin melanoma were given different kinds of immunotherapy; nonspecific immunotherapy with BCG vaccine, adaptive immunotherapy with methotrexate or phytohemagglutinin activated autolymphocytes, and also a combination of polychemotherapy with BCG." | 3.65 | [Immunological reactions of skin melanoma patients to nonspecific and adaptive immunotherapy]. ( Iavorskiĭ, VV; Kadagidze, ZG; Kupin, VI; Malaev, SG; Trapeznikov, NN, 1977) |
| "The incidence of skin cancers of the basal and squamous cell types is extremely low among genetically black-skinned human beings, whereas these types of skin cancers are common among Caucasians, especially those who live in geographic areas of high sun exposure." | 2.67 | Effects of ultraviolet B light on cutaneous immune responses of humans with deeply pigmented skin. ( Metzman, MS; Schmieder, GJ; Streilein, JW; Taylor, JR; van den Berg, JW; Vermeer, M; Yoshikawa, T, 1991) |
| "Basal cell carcinomas (BCC) and squamous cell carcinomas (SCC) show clinical and epidemiological differences not accounted for by different ultraviolet radiation exposure." | 1.29 | Reduced experimental contact sensitivity in squamous cell but not basal cell carcinomas of skin. ( de Berker, D; Ibbotson, S; Idle, JR; Matthews, JN; Rees, JL; Simpson, NB, 1995) |
| "We have studied experimentally induced contact sensitivity to dinitrochlorobenzene by measuring increases in skin-fold thickness." | 1.29 | Reduced experimental contact sensitivity in squamous cell but not basal cell carcinomas of skin. ( de Berker, D; Ibbotson, S; Idle, JR; Matthews, JN; Rees, JL; Simpson, NB, 1995) |
| "The DNCB-method in malignant melanoma is yet in the experimental stage and is not recommended for general use in practice." | 1.26 | [Adjuvant DNCB immunotherapy in malignant melanoma]. ( Djawari, D; Weidner, F, 1979) |
| "3 melanoma patients suffering from skin metastases were treated by epifocal DNCB-application." | 1.26 | [Adjuvant DNCB immunotherapy in malignant melanoma]. ( Djawari, D; Weidner, F, 1979) |
| "Distant metastases may react--but normally these metastases cannot be removed." | 1.26 | [Treatment of malignant melanoma with dinitrochlorobenzene ointment]. ( Ehring, F; Loth, H, 1978) |
| "Immunotherapy against cancer in animals has been established." | 1.25 | Immunotherapy of malignancy in humans. Current status. ( Eilber, FR; Holmes, EC; Morton, DL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (78.87) | 18.7374 |
| 1990's | 10 (14.08) | 18.2507 |
| 2000's | 5 (7.04) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pereira de Oliveira, WR | 1 |
| Carrasco, S | 1 |
| Neto, CF | 1 |
| Rady, P | 1 |
| Tyring, SK | 1 |
| Meykadeh, N | 1 |
| Hengge, UR | 1 |
| von Nida, J | 1 |
| Quirk, C | 1 |
| Herrmann, G | 1 |
| Groth, W | 1 |
| Krieg, T | 1 |
| Mauch, C | 2 |
| Terheyden, P | 1 |
| Kortüm, AK | 1 |
| Schulze, HJ | 1 |
| Durani, B | 1 |
| Remling, R | 1 |
| Junghans, V | 1 |
| Schadendorf, D | 1 |
| Beiteke, U | 1 |
| Jünger, M | 1 |
| Becker, JC | 2 |
| Bröcker, EB | 3 |
| Strauss, GH | 2 |
| Bridges, BA | 2 |
| Greaves, M | 1 |
| Hall-Smith, P | 1 |
| Price, M | 1 |
| Vella-Briffa, D | 1 |
| Thiers, BH | 1 |
| Korosteleva, TA | 2 |
| Vagner, RI | 1 |
| Veresova, OV | 1 |
| Potapenkova, LS | 2 |
| Weimar, VM | 1 |
| Ceilley, RI | 1 |
| Goeken, JA | 1 |
| Dionigi, R | 1 |
| Dominioni, L | 1 |
| Gnes, F | 1 |
| Bonera, A | 1 |
| Prati, U | 1 |
| Scarponi, A | 1 |
| Robustelli Della Cuna, G | 1 |
| Pavesi, L | 1 |
| Campani, M | 1 |
| Moszkowska, G | 1 |
| Jassem, J | 1 |
| Kondrat, W | 1 |
| Kopacz, A | 1 |
| Goszczyńska, E | 1 |
| Takeuchi, R | 1 |
| Hori, M | 1 |
| Shine, T | 1 |
| Wallack, MK | 1 |
| Ehring, E | 1 |
| Loth, H | 2 |
| Djawari, D | 2 |
| Körner, E | 1 |
| Haneke, E | 1 |
| de Berker, D | 1 |
| Ibbotson, S | 1 |
| Simpson, NB | 1 |
| Matthews, JN | 1 |
| Idle, JR | 1 |
| Rees, JL | 1 |
| Taylor, JR | 4 |
| Schmieder, GJ | 3 |
| Shimizu, T | 2 |
| Tie, C | 1 |
| Streilein, JW | 4 |
| Strobbe, LJ | 1 |
| Hart, AA | 1 |
| Rümke, P | 1 |
| Israels, SP | 1 |
| Nieweg, OE | 1 |
| Kroon, BB | 1 |
| Trcka, J | 1 |
| Kämpgen, E | 2 |
| Schwaaf, A | 1 |
| Vonderheid, EC | 2 |
| Ekbote, SK | 1 |
| Kerrigan, K | 1 |
| Kalmanson, JD | 1 |
| Van Scott, EJ | 2 |
| Rook, AH | 1 |
| Abrams, JT | 1 |
| Göring, HD | 1 |
| Zierner, A | 1 |
| Kröning, Y | 1 |
| Trebing, D | 1 |
| Kripke, ML | 2 |
| Lofgreen, JS | 1 |
| Beard, J | 1 |
| Jessup, JM | 2 |
| Fisher, MS | 1 |
| van der Harst-Oostveen, CJ | 1 |
| van Vloten, WA | 1 |
| Holmes, EC | 1 |
| Eilber, FR | 1 |
| Morton, DL | 3 |
| Hazrati, E | 1 |
| Hoomand, A | 1 |
| Pritchard, DJ | 1 |
| Ritts, RE | 1 |
| Taylor, WF | 1 |
| Miller, GC | 1 |
| Dodd, MJ | 1 |
| Clark, WH | 1 |
| Mastrangelo, MJ | 1 |
| Ainsworth, AM | 1 |
| Berd, D | 1 |
| Bellet, RE | 1 |
| Bernardino, EA | 1 |
| Goodnight, JE | 1 |
| Aranha, GV | 1 |
| McKhann, CF | 1 |
| Simmons, RL | 1 |
| Grage, TB | 1 |
| Ryzhkov, VI | 1 |
| Khachaturian, LM | 1 |
| Weidner, F | 1 |
| Ehring, F | 1 |
| Cohen, MH | 2 |
| Felix, EL | 1 |
| Weese, JL | 1 |
| Herberman, RB | 1 |
| Duchková, H | 3 |
| Richter, J | 3 |
| Kubíková, M | 2 |
| Gutterman, JU | 1 |
| Mavligit, G | 1 |
| Reed, R | 1 |
| Richman, S | 1 |
| McBride, CE | 1 |
| Hersh, EM | 1 |
| Klein, E | 2 |
| Rosner, D | 1 |
| Holtermann, OA | 1 |
| Stoll, HL | 1 |
| Song, SY | 1 |
| Burg, G | 1 |
| Braun-Falco, O | 1 |
| Wätzig, V | 2 |
| Johnson, WC | 1 |
| Grekin, DA | 1 |
| Asbell, SO | 1 |
| Rangel, DM | 1 |
| Golub, SH | 1 |
| Gersten, MJ | 1 |
| Hadden, EM | 1 |
| Kaplan, MH | 1 |
| Pinsky, CM | 1 |
| Armstrong, D | 1 |
| Hadden, JW | 1 |
| Trapeznikov, NN | 1 |
| Iavorskiĭ, VV | 1 |
| Kadagidze, ZG | 1 |
| Malaev, SG | 1 |
| Kupin, VI | 1 |
| Leshaw, S | 1 |
| Simon, RS | 1 |
| Bear, RL | 1 |
| Kokoschka, EM | 1 |
| Cerni, C | 1 |
| Micksche, M | 1 |
| Illig, L | 1 |
| Paul, E | 1 |
| Chorzelski, T | 1 |
| Langner, A | 1 |
| Gliński, W | 1 |
| Vanwijck, R | 1 |
| Bouillenne, C | 1 |
| Malek-Mansour, S | 2 |
| Florman, AL | 1 |
| Holzman, RS | 1 |
| Vanwicjk, R | 1 |
| Rustin, P | 1 |
| Castermans-Elias, S | 1 |
| Castermans, A | 1 |
| Meneghini, CL | 1 |
| Angelini, G | 1 |
| Bonifazi, E | 1 |
| Bulkley, GB | 1 |
| Banks, PM | 1 |
| Char, DH | 1 |
| Ketcham, AS | 1 |
| Kurtenkov, OA | 1 |
| Mirme, KhIu | 1 |
| Tseng, C | 1 |
| Hoffman, B | 1 |
| Kurimoto, I | 1 |
| Vermeer, M | 1 |
| Yoshikawa, T | 2 |
| van den Berg, JW | 2 |
| Metzman, MS | 1 |
| Rae, V | 1 |
| Bruins-Slot, W | 1 |
| Sigg, C | 1 |
| Schnyder, UW | 1 |
| Valsecchi, R | 1 |
| Foiadelli, L | 1 |
| Reseghetti, A | 1 |
| Cainelli, T | 1 |
| Budzanowska, E | 1 |
| Pawlicki, M | 1 |
| Mayerhausen, W | 2 |
| Remy, W | 2 |
| Dorn, R | 1 |
| Ulm, K | 1 |
| Nomura, S | 1 |
| Romaguera Sagrera, C | 1 |
| Castel, R | 1 |
| Pedragosa, R | 1 |
| Piñol Aguade, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Photochemotherapy of Acute Graft-versus-host Disease (aGVHD) of the Skin - is Graft-versus-leukemia Preserved in Patients Transplanted for Acute Leukemia?[NCT02631993] | 47 participants (Actual) | Observational | 2014-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for dinitrochlorobenzene and Skin Neoplasms
| Article | Year |
|---|---|
Some DNA-repair-deficient human syndromes and their implications for human health.
Topics: Adolescent; Ataxia Telangiectasia; Cockayne Syndrome; Dinitrochlorobenzene; DNA Repair; Dwarfism; Fe | 1981 |
Immunotherapy of malignant melanoma.
Topics: Antigens, Neoplasm; BCG Vaccine; Cholera Vaccines; Clinical Trials as Topic; Dacarbazine; Dinitrochl | 1982 |
Current concepts of the biology of human cutaneous malignant melanoma.
Topics: Antibodies, Neoplasm; Antigens, Neoplasm; Chromosome Aberrations; Dinitrochlorobenzene; Female; Huma | 1977 |
The role of immunotherapy in the management of patients with malignant melanoma.
Topics: Bacterial Vaccines; BCG Vaccine; Corynebacterium; Dacarbazine; Dinitrochlorobenzene; Drug Therapy, C | 1979 |
Immunology and immunotherapy of human-malignant melanoma: historic review and perspectives for the future.
Topics: Animals; Antibodies, Neoplasm; Antibody Formation; BCG Vaccine; Cell Migration Inhibition; Dinitroch | 1975 |
Nonspecific enhancers of resistance in man.
Topics: Adjuvants, Immunologic; Animals; Ascorbic Acid; Bacteria; BCG Vaccine; Dinitrochlorobenzene; Endotox | 1975 |
5 trials available for dinitrochlorobenzene and Skin Neoplasms
| Article | Year |
|---|---|
Immunotherapy of malignant melanoma.
Topics: Antigens, Neoplasm; BCG Vaccine; Cholera Vaccines; Clinical Trials as Topic; Dacarbazine; Dinitrochl | 1982 |
Topical dinitrochlorobenzene combined with systemic dacarbazine in the treatment of recurrent melanoma.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemoth | 1997 |
Intralesional treatment of recurrent metastatic cutaneous malignant melanoma: a randomized prospective study of intralesional Bacillus Calmette-Guerin versus intralesional dinitrochlorobenzene.
Topics: Adult; Aged; Antigens; Antigens, Neoplasm; BCG Vaccine; Cell Migration Inhibition; Dinitrochlorobenz | 1978 |
Effects of ultraviolet B light on cutaneous immune responses of humans with deeply pigmented skin.
Topics: Adult; Dermatitis, Contact; Dinitrochlorobenzene; Female; Haptens; Humans; Immune Tolerance; Langerh | 1991 |
Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans.
Topics: Adult; Aged; Dermatitis, Contact; Dinitrochlorobenzene; Disease Susceptibility; Dose-Response Relati | 1990 |
61 other studies available for dinitrochlorobenzene and Skin Neoplasms
| Article | Year |
|---|---|
Nonspecific cell-mediated immunity in patients with epidermodysplasia verruciformis.
Topics: Adolescent; Adult; Case-Control Studies; CD4-CD8 Ratio; Dinitrochlorobenzene; Epidermodysplasia Verr | 2003 |
[Topical immunomodulators in dermatology].
Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aged; Aged, 80 and over; Aminoquinolines; As | 2003 |
Successful treatment of in-transit melanoma metastases using topical 2-4 dinitrochlorobenzene.
Topics: Administration, Topical; Aged; Biopsy, Needle; Combined Modality Therapy; Dinitrochlorobenzene; Dise | 2003 |
Complete remission of Merkel cell carcinoma of the scalp with local and regional metastases after topical treatment with dinitrochlorbenzol.
Topics: Adjuvants, Immunologic; Administration, Topical; Aged; Carcinoma, Merkel Cell; Dinitrochlorobenzene; | 2004 |
Chemoimmunotherapy for cutaneous melanoma with dacarbazine and epifocal contact sensitizers: results of a nationwide survey of the German Dermatologic Co-operative Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dinitrochlorobenzene; Dise | 2007 |
Inhibition of delayed hypersensitivity reaction in skin (DNCB test) by 8-methoxypsoralen photochemotherapy. Possible basis for pseudo-promoting action in skin carcinogenesis?
Topics: Adolescent; Adult; Aged; Cocarcinogenesis; Dinitrochlorobenzene; Female; Furocoumarins; Humans; Immu | 1980 |
[Correlation of the level of humoral cytotoxins and delayed hypersensitivity skin reactions with survival of patients with melanoma of the skin].
Topics: Adult; Aged; Antibody Formation; Cytotoxins; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed | 1983 |
Cell-mediated immunity in patients with basal and squamous cell skin cancer.
Topics: Adult; Aged; B-Lymphocytes; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dinitrochlorobenzene; F | 1980 |
Sequential evaluation of immunoreactivity in patients with melanoma undergoing surgery and adjuvant therapy.
Topics: Adult; Aged; Chemotaxis, Leukocyte; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Immuno | 1980 |
Some aspects of cell-mediated hypersensitivity in patients with melanoma.
Topics: Adult; Aged; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Le | 1980 |
[Effect of contact hypersensitivity on experimental carcinogenesis (author's transl)].
Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Mice; Mice, Inbred Strains; Neoplasms, Experimen | 1980 |
[20-methylcholanthrene-induced mice skin cancer: Part 3: Studies on co-carcinogenic and suppressive factors (author's transl)].
Topics: Animals; Croton Oil; Dinitrochlorobenzene; Immunosuppression Therapy; Male; Methylcholanthrene; Mice | 1981 |
PUVA: gambling with a system.
Topics: Animals; Dinitrochlorobenzene; DNA Repair; Humans; Immunosuppression Therapy; Photochemotherapy; Pso | 1982 |
Inflammatory oncotaxis after testing the skin of the cancer patient.
Topics: Adenocarcinoma; Aged; Colonic Neoplasms; Dinitrochlorobenzene; Humans; Male; Skin Neoplasms; Skin Te | 1981 |
DNCB skin test in cases of malignant melanoma.
Topics: Dinitrochlorobenzene; Humans; Melanoma; Nitrobenzenes; Skin Neoplasms; Skin Tests | 1981 |
[Cross allergies following sensitization with dinitrochlorbenzol (DNCB)].
Topics: Cross Reactions; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Immunotherapy; Melanoma; N | 1980 |
Reduced experimental contact sensitivity in squamous cell but not basal cell carcinomas of skin.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Case-Control Studies; Dermatitis, Contact; Dinitroc | 1995 |
Interrelationship between ultraviolet light and recurrent herpes simplex infections in man.
Topics: Adult; Dermatitis, Contact; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Dose-Response Re | 1994 |
[Immunochemotherapy of malignant melanoma. Epifocal administration of dinitrochlorobenzene (DNCB) combined with systemic chemotherapy with dacarbazine (DTIC)].
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Th | 1998 |
The prognostic significance of delayed hypersensitivity to dinitrochlorobenzene and mechlorethamine hydrochloride in cutaneous T cell lymphoma.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Dinitrochlorobenzene; Disease P | 1998 |
Effective combined immunochemotherapy with dinitrochlorobenzene and fotemustine in skin and brain metastases of melanoma.
Topics: Allergens; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dermatitis, Allergic C | 1998 |
In vivo immune responses of mice during carcinogenesis by ultraviolet irradiation.
Topics: Animals; Antigens, Neoplasm; Dinitrochlorobenzene; Graft Rejection; Graft vs Host Reaction; Hypersen | 1977 |
Delayed-type hypersensitivity in patients with mycosis fungoides.
Topics: Adult; Aged; Antigens, Fungal; Candida albicans; Dermatitis, Exfoliative; Dinitrochlorobenzene; Fema | 1978 |
Immunotherapy of malignancy in humans. Current status.
Topics: Adjuvants, Immunologic; Antigens, Neoplasm; BCG Vaccine; Carcinoma, Basal Cell; Carcinoma, Squamous | 1975 |
The keloidal diathesis, a resistant state to malignancies?
Topics: Dinitrochlorobenzene; Disease Susceptibility; Humans; Keloid; Leukocyte Count; Skin Neoplasms; Skin | 1977 |
A prospective study of immune responsiveness in human melanoma. I. Assessment of initial pretreatment status with stage of disease.
Topics: Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; In Vitro Techni | 1978 |
BCG in cancer therapy: theoretical bases of immunotherapy.
Topics: Antigens, Neoplasm; BCG Vaccine; Dinitrochlorobenzene; Humans; Immunity, Cellular; Immunotherapy; Ly | 1979 |
Effects of UV radiation on the immune system: consequences for UV carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Fibrosarcoma; Hypersensitivity, Delayed; Im | 1979 |
Recall skin-test antigens and the prognosis of stage I melanoma.
Topics: Adult; Aged; Antigens; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Intradermal Tests; M | 1979 |
[Skin reactions of delayed hypersensitivity in melanoblastoma].
Topics: Adult; Aged; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunity, | 1979 |
[Adjuvant DNCB immunotherapy in malignant melanoma].
Topics: Adult; Aged; Dinitrochlorobenzene; Female; Humans; Male; Melanoma; Melphalan; Middle Aged; Neoplasm | 1979 |
[Treatment of malignant melanoma with dinitrochlorobenzene ointment].
Topics: Aged; Dinitrochlorobenzene; Female; Humans; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrobenzene | 1978 |
[Contribution to treatment of malignant melanoblastoma by the local application of DNCB (author's transl)].
Topics: Administration, Topical; Aged; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Melanoma; N | 1978 |
Nonspecific antigen reactions.
Topics: Administration, Topical; Antibody Formation; Antigens; Antineoplastic Agents; BCG Vaccine; Breast Ne | 1976 |
[1-Chloro-2,4-dinitrobenzene ointment for sensitization, testing and therapy of malignant melanoma patients].
Topics: Aged; Chemical Phenomena; Chemistry; Dinitrochlorobenzene; Female; Humans; Male; Melanoma; Middle Ag | 1977 |
[Immunotherapy with DNCB in mycosis fungoides].
Topics: Dinitrochlorobenzene; Humans; Immunotherapy; Male; Middle Aged; Mycosis Fungoides; Nitrobenzenes; Sk | 1977 |
Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results.
Topics: Administration, Topical; Aged; Desensitization, Immunologic; Dinitrochlorobenzene; Drug Hypersensiti | 1977 |
Demonstration of lymphocyte blastogenesis--inhibiting factors in sera of melanoma patients.
Topics: Adolescent; Adult; Aged; Dinitrochlorobenzene; Female; Humans; In Vitro Techniques; Lymphocyte Activ | 1977 |
Immunologic defects in melanoma patients: lack of effect of BCG therapy.
Topics: BCG Vaccine; Dinitrochlorobenzene; Humans; Lectins; Leukocyte Count; Lymphocyte Activation; Melanoma | 1977 |
[Immunological reactions of skin melanoma patients to nonspecific and adaptive immunotherapy].
Topics: Antigen-Antibody Reactions; BCG Vaccine; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Im | 1977 |
Failure to induce tolerance to mechlorethamine hydrochloride.
Topics: Dermatitis, Contact; Dinitrochlorobenzene; Humans; Immune Tolerance; Mechlorethamine; Mycosis Fungoi | 1977 |
Active specific and active non-specific immunotherapy in patients with malignant melanoma.
Topics: Adult; Aged; Antigens, Neoplasm; BCG Vaccine; Cell Migration Inhibition; Dinitrochlorobenzene; Femal | 1977 |
[DNCB immunotherapy for removal of melanoma skin metastases].
Topics: Dinitrochlorobenzene; Humans; Immunotherapy; Melanoma; Neoplasm Metastasis; Nitrobenzenes; Skin Neop | 1977 |
[The nonspecific epifocal Malek-Mansour immunotherapy of malignant cutaneous melanoma using DNCB].
Topics: Administration, Topical; Adult; Aged; Cell Transformation, Neoplastic; Dinitrochlorobenzene; Female; | 1976 |
Immunotherapeutic approaches to skin cancer.
Topics: Administration, Topical; Antineoplastic Agents; BCG Vaccine; Carcinoma, Basal Cell; Dinitrochloroben | 1976 |
[Immunotherapy in dermatology].
Topics: Administration, Topical; Dinitrochlorobenzene; Humans; Immunotherapy; Nitrobenzenes; Skin Neoplasms | 1976 |
Potentiation and arming of lymphocyte mediated immunity by sera from melanoma patients.
Topics: Agglutination Tests; Antibodies, Anti-Idiotypic; Cell Line; Cytotoxicity Tests, Immunologic; Dinitro | 1975 |
[Problems of immunotherapy in malignant melanoblastoma].
Topics: BCG Vaccine; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Immunotherapy; Male; Melanoma | 1975 |
[Preliminary results of immuno-surgical treatment of primary melanoma (author's transl)].
Topics: Adult; Aged; Autoantibodies; Cytotoxicity Tests, Immunologic; Dinitrochlorobenzene; Female; Humans; | 1975 |
Immunity in tumours of the skin. Studies on cell-mediated immune reactions.
Topics: Adult; Aged; Antigens, Bacterial; Benzalkonium Compounds; Carcinoma, Basal Cell; Carcinoma, Squamous | 1975 |
Long-term spontaneous regression of malignant melanoma with visceral metastases. Report of a case with immunologic profile.
Topics: Autoantigens; Cell Migration Inhibition; Cytotoxicity Tests, Immunologic; Dinitrochlorobenzene; Fema | 1975 |
[Activity of 2,4 dinitrochlorbenzene skin tests during the course of immunotherapy of malignant melanomas].
Topics: BCG Vaccine; Dinitrochlorobenzene; Humans; Melanoma; Nitrobenzenes; Skin Neoplasms; Skin Tests | 1975 |
[The effect of local non-specific sensitization with 2,4-dinitrochlorbenzene on chemical carcinogenesis].
Topics: Animals; Benzopyrenes; Dinitrochlorobenzene; Immunization; Male; Mice; Mice, Inbred C57BL; Nitrobenz | 1975 |
Analysis of effects of ultraviolet B radiation on induction of primary allergic reactions.
Topics: Adult; Age Factors; Dermatitis, Contact; Dinitrochlorobenzene; Humans; Middle Aged; Prospective Stud | 1992 |
Successful immunotherapy by dinitrochlorobenzene in a case of recurrent acrolentiginous melanoma.
Topics: Administration, Topical; Aged; Dinitrochlorobenzene; Female; Foot Diseases; Humans; Immunotherapy; M | 1990 |
Generalized urticaria from DNCB.
Topics: Aged; Combined Modality Therapy; Dinitrochlorobenzene; Drug Eruptions; Female; Humans; Immunotherapy | 1986 |
An attempt at topical DNCB immunomodulation in advanced malignant melanoma.
Topics: Administration, Topical; Adult; Aged; Dinitrochlorobenzene; Female; Humans; Lymphatic Metastasis; Me | 1988 |
[Testing of cellular immune reactivity in melanoma patients with diphenylcyclopropenone in comparison to dinitrochlorobenzol].
Topics: Cyclopropanes; Dinitrochlorobenzene; Humans; Immune Tolerance; Immunity, Cellular; Melanoma; Patch T | 1987 |
[Decrease in immunoreactivity in melanoma. Analysis of DNCB tests in the literature].
Topics: Dinitrochlorobenzene; Humans; Immune Tolerance; Melanoma; Neoplasm Metastasis; Neoplasm Staging; Ski | 1986 |
[Studies of contact hypersensitivity and immune tolerance in experimental neoplasms].
Topics: Animals; Benzenesulfonates; Dermatitis, Contact; Dinitrochlorobenzene; Immune Tolerance; Mice; Skin | 1985 |
[Treatment of epithelioms with DNCB].
Topics: Dinitrochlorobenzene; Drug Evaluation; Female; Humans; Injections, Intramuscular; Lip Neoplasms; Mal | 1974 |