dinitrochlorobenzene has been researched along with Pregnancy in 30 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A contact dermatitis mouse model was established by sensitizing the dorsal skin of BALB/c mice using the contact allergen, 2,4-dinitrochlorobenzene (DNCB), and molecular consequences of topical application of PPE were investigated." | 7.88 | Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis. ( Heo, JH; Heo, Y; Kim, M; Lee, HJ; Shin, HY, 2018) |
| "A contact dermatitis mouse model was established by sensitizing the dorsal skin of BALB/c mice using the contact allergen, 2,4-dinitrochlorobenzene (DNCB), and molecular consequences of topical application of PPE were investigated." | 3.88 | Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis. ( Heo, JH; Heo, Y; Kim, M; Lee, HJ; Shin, HY, 2018) |
| "Offspring of toluene diisocyanate but not dinitrochlorobenzene-treated mothers developed an asthmatic phenotype following allergen sensitization and challenge, seen as increased Penh values, airway inflammation, bronchoalveolar lavage total cell counts and eosinophilia, and Th2 cytokine imbalance in the lung." | 3.74 | Maternal allergic contact dermatitis causes increased asthma risk in offspring. ( Arredouani, MS; Fedulov, A; Hubeau, C; Kobzik, L; Lim, RH, 2007) |
| "The nonspecific cell-mediated immunocompetence of 51 patients with gestational trophoblastic disease (GTD), including 16 patients with hydatid mole (HM), 24 with nonmetastatic trophoblastic neoplasia (NTN) and 15 with metastatic TN (MTN), was studied with the use of both in vitro and in vivo parameters of cell-mediated immunity (CMI) such as lymphocyte blastogenic response to phytohemagglutinin (PHA), subpopulation constitution, and delayed cutaneous hypersensitivity responses to 2,4-dinitrochlorobenzene (DNCB) and to purified protein derivative of tuberculin (PPD)." | 3.66 | Clinical studies on cell-mediated immunity in gestational trophoblastic disease: nonspecific cellular immunocompetence in patients with hydatid mole and trophoblastic neoplasia. ( Fujisaki, S; Sasaki, T, 1981) |
| "Cellular hypersensitivity was studied in patients with adenomatous hyperplasia and adenocarcinoma of the endometrium with the use of dinitrochlorobenzene (DNCB) skin tests and inhibition of leukocyte migration by homologous and autologous tumor antigen." | 3.65 | Cellular hypersensitivity in patients with adenomatous hyperplasia and adenocarcinoma of the endometrium. ( Chen, SY; Cohen, CJ; Koffler, D, 1976) |
| "Tricyclic antidepressants (TCAs) are the non-selective amine re-uptake inhibitors, well absorbed from small intestine, cross the blood-brain barrier, distributed in the brain, and are bound to glutathione S-transferase-π (GST-π)." | 1.37 | The inhibition characteristics of human placental glutathione S-transferase-π by tricyclic antidepressants: amitriptyline and clomipramine. ( Dalmizrak, O; Kulaksiz-Erkmen, G; Ozer, N, 2011) |
| "Dinitrochlorobenzene is a skin-sensitizer only and known to induce a Th1 response, while toluene diisocyanate is both a skin and respiratory sensitizer that causes a Th2 response." | 1.34 | Maternal allergic contact dermatitis causes increased asthma risk in offspring. ( Arredouani, MS; Fedulov, A; Hubeau, C; Kobzik, L; Lim, RH, 2007) |
| "By using DNCB delayed hypersensitivity test, the reaction of spontaneous rosette formation (RSRF) and the reaction of inhibition of leucocytes migration the authors examined 55 female patients with different forms of trophoblastic tumors of the uterus and 15 females following the removal of the mole without any signs of the disease concerned." | 1.26 | [Immunological reactivity study of patients with uterine trophoblastic tumors]. ( Grigorova, TM; Kadagidze, ZG; Kovaleva, VL; Stas, TA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (56.67) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Markus, V | 1 |
| Teralı, K | 1 |
| Dalmizrak, O | 4 |
| Ozer, N | 4 |
| Heo, JH | 1 |
| Heo, Y | 1 |
| Lee, HJ | 1 |
| Kim, M | 1 |
| Shin, HY | 1 |
| Meyer, MR | 1 |
| Richter, LH | 1 |
| Maurer, HH | 1 |
| Alparslan, MM | 1 |
| Danış, Ö | 1 |
| Vaidya, SS | 2 |
| Walsh, SW | 1 |
| Gerk, PM | 2 |
| Kulaksiz-Erkmen, G | 3 |
| ROSENTHAL, SA | 1 |
| BAER, RL | 1 |
| Lim, RH | 1 |
| Arredouani, MS | 1 |
| Fedulov, A | 1 |
| Kobzik, L | 1 |
| Hubeau, C | 1 |
| Sasaki, T | 1 |
| Fujisaki, S | 1 |
| Polak, L | 2 |
| Ricci, G | 1 |
| Caccuri, AM | 1 |
| Lo Bello, M | 1 |
| Rosato, N | 1 |
| Mei, G | 1 |
| Nicotra, M | 1 |
| Chiessi, E | 1 |
| Mazzetti, AP | 1 |
| Federici, G | 1 |
| Kulkarni, AP | 1 |
| Sajan, M | 1 |
| van Haaften, RI | 1 |
| Evelo, CT | 1 |
| Haenen, GR | 1 |
| Bast, A | 1 |
| Keller, AJ | 1 |
| Irvine, WJ | 1 |
| Jordan, J | 1 |
| Loudon, NB | 1 |
| Palatsi, R | 1 |
| Oikarinen, A | 1 |
| Taylor, MA | 1 |
| Israel, BA | 1 |
| Escobar, MR | 1 |
| Berlinerman, D | 1 |
| Parker, D | 1 |
| Sommer, G | 1 |
| Turk, JL | 1 |
| Chandra, RK | 1 |
| Grigorova, TM | 1 |
| Stas, TA | 1 |
| Kadagidze, ZG | 1 |
| Kovaleva, VL | 1 |
| Rea, TH | 1 |
| Rinck, C | 1 |
| Chen, SY | 1 |
| Cohen, CJ | 1 |
| Koffler, D | 1 |
| Vanwijck, R | 1 |
| Bouillenne, C | 1 |
| Malek-Mansour, S | 1 |
| Umanskiĭ, IuA | 1 |
| Ivanetich, KM | 1 |
| Goold, RD | 1 |
| Khanna, A | 1 |
| Khanna, S | 1 |
| Gupta, RM | 1 |
| Gupta, S | 1 |
| Khanna, AK | 1 |
| Khipko, SE | 1 |
| Vasilenko, NM | 1 |
| Garmash, VM | 1 |
2 reviews available for dinitrochlorobenzene and Pregnancy
| Article | Year |
|---|---|
Immunological aspects of contact sensitivity.
Topics: Animals; Cyclophosphamide; Dermatitis, Contact; Desensitization, Immunologic; Dinitrochlorobenzene; | 1980 |
[Theoretical principles of clinical tumor immunology].
Topics: Adsorption; Antigens, Neoplasm; BCG Vaccine; Cell Migration Inhibition; Cytotoxicity Tests, Immunolo | 1975 |
28 other studies available for dinitrochlorobenzene and Pregnancy
| Article | Year |
|---|---|
Assessment of the inhibitory activity of the pyrethroid pesticide deltamethrin against human placental glutathione transferase P1-1: A combined kinetic and docking study.
Topics: Dinitrochlorobenzene; Female; Glutathione; Glutathione S-Transferase pi; Humans; Insecticides; Molec | 2018 |
Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biological Products; Cell Line; Dermatitis, Contact | 2018 |
Methylenedioxy designer drugs: mass spectrometric characterization of their glutathione conjugates by means of liquid chromatography-high-resolution mass spectrometry/mass spectrometry and studies on their glutathionyl transferase inhibition potency.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dinitrochlor | 2014 |
In Vitro Inhibition of Human Placental Glutathione S-Transferase by 3-Arylcoumarin Derivatives.
Topics: Antineoplastic Agents; Coumarins; Dinitrochlorobenzene; Drug Design; Drug Resistance, Neoplasm; Enzy | 2015 |
Application of human placental villous tissue explants to study ABC transporter mediated efflux of 2,4-dinitrophenyl-S-glutathione.
Topics: Adult; ATP-Binding Cassette Transporters; Biological Transport; Chorionic Villi; Dinitrochlorobenzen | 2011 |
The inhibition characteristics of human placental glutathione S-transferase-π by tricyclic antidepressants: amitriptyline and clomipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dinitrochlorobenzene; Enzyme Assays; | 2011 |
Possible prenatal impact of sertraline on human placental glutathione S-transferase-π.
Topics: Antidepressive Agents, Tricyclic; Dinitrochlorobenzene; Enzyme Inhibitors; Female; Glutathione; Glut | 2012 |
Evaluation of the in vitro inhibitory impact of hypericin on placental glutathione S-transferase pi.
Topics: Anthracenes; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Glutath | 2012 |
ACTIVELY ACQUIRED TOLERANCE TO DINITROCHLOROBENZENE. TESTS IN NEWBORN GUINEA PIGS.
Topics: Animals; Animals, Newborn; Dinitrochlorobenzene; Drug Hypersensitivity; Female; Guinea Pigs; Humans; | 1963 |
Maternal allergic contact dermatitis causes increased asthma risk in offspring.
Topics: Animals; Asthma; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Disease | 2007 |
Simultaneous determination of 1-chloro-2,4-dinitrobenzene, 2,4-dinitrophenyl-S-glutathione and its metabolites for human placental disposition studies by high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Dinitrochlorobenzene; Female; Glutathione; Humans; Pl | 2007 |
Clinical studies on cell-mediated immunity in gestational trophoblastic disease: nonspecific cellular immunocompetence in patients with hydatid mole and trophoblastic neoplasia.
Topics: Adult; Azides; B-Lymphocytes; Dinitrochlorobenzene; DNA; Drug Hypersensitivity; Female; Humans; Hyda | 1981 |
Structural flexibility modulates the activity of human glutathione transferase P1-1. Role of helix 2 flexibility in the catalytic mechanism.
Topics: Binding Sites; Catalysis; Cysteine; Dinitrochlorobenzene; Female; Glutathione Transferase; Humans; I | 1996 |
Lipoxygenase-another pathway for glutathione conjugation of xenobiotics: A study with human term placental lipoxygenase and ethacrynic acid.
Topics: Chromatography, Affinity; Dinitrochlorobenzene; Ethacrynic Acid; Female; Glutathione; Humans; Linole | 1999 |
alpha-Tocopherol inhibits human glutathione S-transferase pi.
Topics: Antioxidants; Cytosol; Dinitrochlorobenzene; Enzyme Inhibitors; Female; Glutathione; Glutathione S-T | 2001 |
Phytohemagglutin-induced lymphocyte transformation in oral contraceptive users.
Topics: Adolescent; Adult; alpha-Macroglobulins; Autoantibodies; Child; Contraceptives, Oral; Contraceptives | 1977 |
Hormonal analysis and delayed hypersensitivity reactions in identical twins with severe acne.
Topics: Acne Vulgaris; Adolescent; Adult; Dinitrochlorobenzene; Diseases in Twins; Female; Humans; Hypersens | 1979 |
In vitro and in vivo parameters of humoral and cellular immunity in an animal model for protein-calorie malnutrition.
Topics: Animals; Antibody Formation; Blood Proteins; Cell Transformation, Neoplastic; Complement System Prot | 1979 |
Variation in guinea pig responsiveness.
Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Arsenicals; Ascorbic Acid; Cortiso | 1975 |
Fetal malnutrition and postnatal immunocompetence.
Topics: Antibody Formation; Birth Weight; Chemotaxis; Clostridium tetani; Dinitrochlorobenzene; Female; Gest | 1975 |
[Immunological reactivity study of patients with uterine trophoblastic tumors].
Topics: Antigen-Antibody Reactions; Cell Migration Inhibition; Dinitrochlorobenzene; Female; Humans; Hyperse | 1979 |
Quantitative enhancement of dinitrochlorobenzene responsivity in women receiving oral contraceptives.
Topics: Antigens; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Dinitrochlorobenzene; Drug Combinat | 1979 |
Induction of tolerance to DNCB-contact sensitivity in guinea pig fetuses.
Topics: Aging; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Fetus; Guinea Pigs; Immune Tolera | 1979 |
Cellular hypersensitivity in patients with adenomatous hyperplasia and adenocarcinoma of the endometrium.
Topics: Adenocarcinoma; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Migration Inhibition; Dinitrochlo | 1976 |
Potentiation and arming of lymphocyte mediated immunity by sera from melanoma patients.
Topics: Agglutination Tests; Antibodies, Anti-Idiotypic; Cell Line; Cytotoxicity Tests, Immunologic; Dinitro | 1975 |
A rapid equilibrium random sequential bi-bi mechanism for human placental glutathione S-transferase.
Topics: Binding Sites; Binding, Competitive; Catalysis; Computer Simulation; Dinitrochlorobenzene; Female; G | 1989 |
Immunological status of trophoblastic neoplasia.
Topics: Candida; Choriocarcinoma; Dinitrochlorobenzene; Female; Humans; Hydatidiform Mole; Hypersensitivity, | 1985 |
[Reproductive function of white rats under inhalational exposure to dinitrochlorobenzene].
Topics: Animals; Dinitrochlorobenzene; Embryo, Mammalian; Environmental Exposure; Female; Genes, Dominant; G | 1985 |