dinitrochlorobenzene has been researched along with Necrosis in 6 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Profound alterations in the dermal microvasculature and the closely related fixed tissue mast cells were observed in allergic contact dermatitis reactions to dinitrochlorobenzene and urushiol in man." | 3.65 | Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells. ( Dvorak, AM; Dvorak, HF; Mihm, MC, 1976) |
| " In this study, the changes in the cellular and extracellular concentrations of these alpha-oxoaldehydes were investigated in murine P388D1 macrophages during necrotic cell death induced by median toxic concentrations of hydrogen peroxide and 1-chloro-2,4-dinitrobenzene (CDNB)." | 1.30 | Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity. ( Abordo, EA; Minhas, HS; Thornalley, PJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohtani, T | 1 |
| Mizuashi, M | 1 |
| Nakagawa, S | 1 |
| Sasaki, Y | 1 |
| Fujimura, T | 1 |
| Okuyama, R | 1 |
| Aiba, S | 1 |
| Nukada, Y | 1 |
| Ito, Y | 1 |
| Miyazawa, M | 1 |
| Sakaguchi, H | 1 |
| Nishiyama, N | 1 |
| Abordo, EA | 1 |
| Minhas, HS | 1 |
| Thornalley, PJ | 1 |
| Ferry, AP | 1 |
| Meltzer, MA | 1 |
| Taub, RN | 1 |
| Krawiec, DR | 1 |
| Gaafar, SM | 1 |
| Dvorak, AM | 1 |
| Mihm, MC | 1 |
| Dvorak, HF | 1 |
6 other studies available for dinitrochlorobenzene and Necrosis
| Article | Year |
|---|---|
TGF-beta1 dampens the susceptibility of dendritic cells to environmental stimulation, leading to the requirement for danger signals for activation.
Topics: Adenosine Triphosphate; Antigens, CD34; Apoptosis; Cell Differentiation; Cells, Cultured; Coculture | 2009 |
The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells.
Topics: Acetaldehyde; Allergens; Amino Acid Chloromethyl Ketones; Apoptosis; B7-2 Antigen; Caspase Inhibitor | 2011 |
Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Glutathione; Glyoxal; Guanidi | 1999 |
Immunotherapy with dinitrochlorobenzene (DNCB) for recurrent squamous cell tumor of conjunctiva.
Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Carcinoma, Squamous Cell; Conjunctiva; Dinit | 1976 |
A comparative study of allergic and primary irritant contact dermatitis with dinitrochlorobenzene (DNCB) in dogs.
Topics: Administration, Topical; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Dogs; Drug Hypersensiti | 1975 |
Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells.
Topics: Administration, Topical; Adolescent; Adult; Antigens; Arm; Basement Membrane; Capillaries; Capillary | 1976 |