dinitrochlorobenzene has been researched along with Myasthenia Gravis in 5 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven thymectomized and ten non-thymectomized patients with myasthenia gravis, matched with respect to sex, age, duration and severity of the disease were investigated with respect to routine clinical features, electrophysiological examination, HLA-typing, auto-antibodies, lymphocyte subpopulations in peripheral blood, Concanavalin A-induced release of leucocyte migration inhibitory factor (LIF), in vitro lymphocyte activation by mitogens and antigens and response to primary immunization with dinitrochlorobenzene measured in vivo and in vitro." | 3.66 | Immunological studies in thymectomized and non-thymectomized patients with myasthenia gravis. ( Andersen, V; Bendtzen, K; Fulpius, BW; Krarup, C; Monnier, VM; Permin, H; Platz, P; Søeberg, B; Sørensen, SF; Thomsen, M, 1978) |
| "1-Chloro-2,4-dinitrobenzene (DNCB) contact sensitivity and other T lymphocyte functions were studied in thymectomized and non-thymectomized patients with myasthenia gravis." | 1.26 | Effect of adult thymectomy on the development of 1-chloro-2,4-dinitrobenzene contact sensitivity and other T lymphocyte functions in patients with myasthenia gravis. ( Hanson, LA; Lindholm, L; Roupe, G, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roupe, G | 2 |
| Lindholm, L | 1 |
| Hanson, LA | 1 |
| Wijermans, P | 1 |
| Oosterhuis, HJ | 1 |
| Astaldi, GC | 1 |
| Schellekens, PT | 1 |
| Astaldi, A | 1 |
| Mendes, N | 1 |
| Kopersztych, S | 1 |
| Saraiva, S | 1 |
| de Assis, JL | 1 |
| Sørensen, SF | 1 |
| Andersen, V | 1 |
| Bendtzen, K | 1 |
| Fulpius, BW | 1 |
| Krarup, C | 1 |
| Monnier, VM | 1 |
| Permin, H | 1 |
| Platz, P | 1 |
| Søeberg, B | 1 |
| Thomsen, M | 1 |
5 other studies available for dinitrochlorobenzene and Myasthenia Gravis
| Article | Year |
|---|---|
Effect of adult thymectomy on the development of 1-chloro-2,4-dinitrobenzene contact sensitivity and other T lymphocyte functions in patients with myasthenia gravis.
Topics: Adolescent; Adult; Aging; Cholinesterase Inhibitors; Concanavalin A; Dermatitis, Contact; Dinitrochl | 1980 |
Influence of adult thymectomy on immunocompetence in patients with myasthenia gravis.
Topics: Adult; Aging; Antibody-Dependent Cell Cytotoxicity; Dinitrochlorobenzene; Humans; Immunoglobulins; L | 1980 |
[Cellular immunity in myasthenia gravis].
Topics: Adult; B-Lymphocytes; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immunity, Cel | 1978 |
Biological factors in contact sensitivity. Studies in mouse and man.
Topics: Age Factors; Animals; Antibody Formation; Dermatitis, Contact; Dinitrochlorobenzene; HLA Antigens; H | 1979 |
Immunological studies in thymectomized and non-thymectomized patients with myasthenia gravis.
Topics: Adolescent; Adult; Aged; Autoantibodies; Autoimmune Diseases; Connective Tissue Diseases; Dinitrochl | 1978 |