dinitrochlorobenzene has been researched along with Lung Neoplasms in 37 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An empirically established chemoimmunotherapy for metastatic melanoma combines the systemic administration of the chemotherapeutic agent dacarbazine (DTIC) with the epifocal application of the contact sensitizer 2,4-dinitrochlorobenzene (DNCB) on cutaneous metastases." | 7.71 | Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002) |
| "This set of experiments was devised to determine the effects of the commonly employed anesthetic induction agent, thiopental, on the incidence of pulmonary metastases in a murine fibrosarcoma system." | 7.65 | Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977) |
| "Subcutaneous (s." | 5.31 | Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002) |
| "This was correlated with an impaired delayed hypersensitivity reaction to the de novo antigen." | 5.26 | Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977) |
| "An empirically established chemoimmunotherapy for metastatic melanoma combines the systemic administration of the chemotherapeutic agent dacarbazine (DTIC) with the epifocal application of the contact sensitizer 2,4-dinitrochlorobenzene (DNCB) on cutaneous metastases." | 3.71 | Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002) |
| "An empirically established chemoimmunotherapy that combines the epifocal application of the contact sensitizer dinitrochlorobenzene (DNCB) to cutaneous metastases with the systemic administration of dacarbazine (DTIC) yields high response rates and results in prolonged survival." | 3.71 | Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model. ( Becker, JC; Bröcker, EB; Fischer, WH; Lutz, WK; Wack, C, 2001) |
| "Delayed hypersensitivity reactions before therapy in 137 patients with lung cancer and in 50 patients with benign thoracic lesions were evaluated by 2,4-dinitrochlorobenzene (DNCB) contact sensitization using the patch test." | 3.66 | Sequential evaluation of DNCB reactivity in patients with primary lung cancer. Correlation with prognosis. ( Fukai, S; Inoue, H; Ishihara, T; Kobayashi, K, 1978) |
| "This set of experiments was devised to determine the effects of the commonly employed anesthetic induction agent, thiopental, on the incidence of pulmonary metastases in a murine fibrosarcoma system." | 3.65 | Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977) |
| "Immunocompetence, as determined by skin reactivity to five microbial antigens, dinitrochlorobenzene (DNCB), and percent and absolute number of total T and B rosette-forming cells (RFC), was assessed before and up to 180 days after radiotherapy in 29 patients with carcinoma of the lung." | 3.65 | Immune evaluation of lung cancer patients undergoing radiation therapy. ( Abbate, J; Kerman, R; Stefani, S, 1976) |
| "Spontaneous remission of pulmonary metastases from renal cell carcinoma was correlated with a positive response to dinitrochlorobenzene (DNCB)." | 3.65 | Immunocompetence and spontaneous regression of metastatic renal cell carcinoma. ( Boasberg, PD; Eilber, FR; Morton, DL, 1976) |
| "Subcutaneous (s." | 1.31 | Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002) |
| "150 patients with lung cancer have been studied from the immunological point of view: the two years that elapsed between the study and processing of the data permitted an evaluation of the prognosis in terms of immunology also." | 1.26 | [Relationships between clinico-therapeutic parameters and immunological status in patients with lung cancer]. ( Bortolotti, F; Calabrò, F; Cecchetto, A; Fattovich, G; Paruzzolo, P; Roviaro, GC; Sartori, F; Tremolada, F; Varoli, F, 1980) |
| "This was correlated with an impaired delayed hypersensitivity reaction to the de novo antigen." | 1.26 | Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977) |
| "The personal series consists of 140 cancer patients followed up over a period of some 3 years and submitted prior to the start of treatment to the DNCB skin test." | 1.26 | [The DNCB skin test and its comparison with the radioimmunological determination of CEA in some types of neoplasms]. ( Bianucci, P; De Rossi, O; Pastorino, G, 1979) |
| "Three mo later, the patient developed brain metastases although X-ray examination showed no pulmonary nodules." | 1.26 | Immunocompetence and spontaneous regression of metastatic renal cell carcinoma. ( Boasberg, PD; Eilber, FR; Morton, DL, 1976) |
| "Spontaneous remission of pulmonary metastases from renal cell carcinoma was correlated with a positive response to dinitrochlorobenzene (DNCB)." | 1.26 | Immunocompetence and spontaneous regression of metastatic renal cell carcinoma. ( Boasberg, PD; Eilber, FR; Morton, DL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (89.19) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eriksson, SE | 1 |
| Prast-Nielsen, S | 1 |
| Flaberg, E | 1 |
| Szekely, L | 1 |
| Arnér, ES | 1 |
| Wack, C | 2 |
| Kirst, A | 1 |
| Becker, JC | 2 |
| Lutz, WK | 2 |
| Bröcker, EB | 2 |
| Fischer, WH | 2 |
| Soresi, V | 1 |
| Invernizzi, G | 1 |
| Schiraldi, G | 1 |
| Borghini, U | 1 |
| Sacerdoti, C | 1 |
| Maruzzi, M | 1 |
| Miyamoto, H | 1 |
| Inoue, S | 1 |
| Jessup, JM | 1 |
| Kahan, BD | 1 |
| LeGrue, SJ | 1 |
| Rutzky, L | 1 |
| Pellis, NR | 1 |
| Fan, XJ | 1 |
| Takanami, I | 1 |
| Nakayama, H | 1 |
| Ishihara, T | 2 |
| Yanai, N | 1 |
| Roviaro, GC | 1 |
| Varoli, F | 1 |
| Sartori, F | 1 |
| Calabrò, F | 1 |
| Bortolotti, F | 1 |
| Tremolada, F | 1 |
| Fattovich, G | 1 |
| Cecchetto, A | 1 |
| Paruzzolo, P | 1 |
| Mello Teggia, P | 1 |
| Smrekar, E | 1 |
| Cimarelli, A | 1 |
| Prencipe, E | 1 |
| Wareing, CJ | 1 |
| Black, SM | 1 |
| Hayes, JD | 1 |
| Wolf, CR | 1 |
| Lundy, J | 1 |
| Lovett, EJ | 1 |
| Conran, P | 1 |
| Alsabti, EA | 1 |
| Stefani, S | 1 |
| Kerman, R | 1 |
| Abbate, J | 1 |
| Wanebo, HJ | 3 |
| Rao, B | 1 |
| Miyazawa, N | 1 |
| Martini, N | 1 |
| Middleman, MP | 1 |
| Oettgen, HF | 2 |
| Beattie, EJ | 2 |
| Cerni, C | 1 |
| Tatra, G | 1 |
| Berger, R | 1 |
| Micksche, M | 1 |
| Banna, P | 1 |
| Stivala, F | 1 |
| Murabito, R | 1 |
| Cordopatri, F | 1 |
| Saggio, A | 1 |
| Mosca, F | 1 |
| Cinà, C | 1 |
| Liebler, GA | 1 |
| Concannon, JP | 1 |
| Magovern, GJ | 1 |
| Dalbow, MH | 1 |
| Hodgson, SE | 1 |
| Benfield, JR | 1 |
| Shors, E | 1 |
| Schick, P | 1 |
| Byfield, PE | 1 |
| Okita, M | 1 |
| Micksche, VM | 1 |
| Słowik-Gabryelska, A | 2 |
| Krzyśko, R | 2 |
| Menzel-Czapiewska, A | 2 |
| Mar'in, ND | 1 |
| Kupin, VI | 1 |
| Kadagidze, ZG | 1 |
| DeMeester, TR | 1 |
| Golomb, HM | 1 |
| Dudek, P | 1 |
| Hunter, RL | 1 |
| Fang, VS | 1 |
| Bianucci, P | 2 |
| Pastorino, G | 2 |
| De Rossi, O | 2 |
| Brondi, P | 1 |
| Plesnicar, S | 1 |
| Rudolf, Z | 1 |
| Lavrencic, D | 1 |
| Pinsky, CM | 1 |
| Inoue, H | 1 |
| Kobayashi, K | 1 |
| Fukai, S | 1 |
| Lukaszewicz, M | 1 |
| Gizycka, D | 1 |
| Morton, DL | 2 |
| Holmes, EC | 2 |
| Golub, SH | 2 |
| Boasberg, PD | 1 |
| Eilber, FR | 1 |
| Shcherban', EI | 1 |
| Strashinina, OA | 1 |
| Vladimirova, VA | 1 |
| Ivanova, LV | 1 |
| Libson, IL | 1 |
| Sone, S | 1 |
| Yata, K | 1 |
| Tsubura, E | 1 |
| Katada, H | 1 |
| Nishikawa, K | 1 |
| Yoneda, T | 1 |
| Kitamura, H | 1 |
| Nakajima, A | 1 |
| Mikami, R | 1 |
| Shaieb, AM | 1 |
| Berman, B | 1 |
| Smith, B | 1 |
| Krumpe, P | 1 |
2 reviews available for dinitrochlorobenzene and Lung Neoplasms
| Article | Year |
|---|---|
[Cellular immunity in lung cancer].
Topics: Cytotoxicity Tests, Immunologic; Dinitrochlorobenzene; Humans; Immunity, Cellular; Lung Neoplasms; L | 1980 |
[Immunology and immunotherapy of lung cancer--experimental and clinical investigations (author's transl)].
Topics: Animals; Antibodies, Neoplasm; Antibody Formation; Antigens, Neoplasm; BCG Vaccine; Cell Migration I | 1978 |
1 trial available for dinitrochlorobenzene and Lung Neoplasms
| Article | Year |
|---|---|
Immunologic defects in lung cancer patients.
Topics: Adenocarcinoma; Clinical Trials as Topic; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; I | 1976 |
34 other studies available for dinitrochlorobenzene and Lung Neoplasms
| Article | Year |
|---|---|
High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy.
Topics: Adenocarcinoma; Apoptosis; Auranofin; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cisplatin | 2009 |
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarb | 2002 |
[Behavior of DNCB and tuberculin skin tests in relation to the various histological types of pulmonary cancer].
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Dinitrochlorobenzene; | 1981 |
Soluble factors from murine and human tumors induce suppressor cells.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Dinitrochlorobenzene; Female; Fibrosarcoma; H | 1984 |
[Delayed hypersensitivity response of the skin to 2,4-dinitrochlorobenzene and old tuberculin in patients with lung cancer].
Topics: Aged; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Lung Neoplasms; Middle Aged; Prognosi | 1983 |
[Methyl heptine carbonate skin test in lung cancer--correlation with stage and prognosis].
Topics: Adult; Aged; Caprylates; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Lung Neopl | 1984 |
[Relationships between clinico-therapeutic parameters and immunological status in patients with lung cancer].
Topics: Antigens; Cytotoxicity Tests, Immunologic; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; | 1980 |
[Initial observations on the use of levamisole in the immunostimulation treatment of patients operated on for lung cancer].
Topics: Dinitrochlorobenzene; Humans; Immunity, Cellular; Levamisole; Lung Neoplasms; Prognosis; Skin Tests | 1981 |
Increased levels of alpha-class and pi-class glutathione S-transferases in cell lines resistant to 1-chloro-2,4-dinitrobenzene.
Topics: Benzene Derivatives; Blotting, Northern; Blotting, Southern; Cell Line; Chlorambucil; Chromatography | 1993 |
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model.
Topics: Animals; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Dinitrochloroben | 2001 |
Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental.
Topics: Anesthetics; Animals; Dinitrochlorobenzene; Fibrosarcoma; Hypersensitivity, Delayed; Immunosuppressi | 1977 |
In vivo and in vitro assays of immunocompetence in bronchogenic carcinoma.
Topics: Aged; Carcinoma, Bronchogenic; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immu | 1979 |
Immune evaluation of lung cancer patients undergoing radiation therapy.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Dinitrochlo | 1976 |
Immune reactivity in primary carcinoma of the lung and its relation to prognosis.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Dinit | 1976 |
Cell-mediated immunity in patients with cervical cancer.
Topics: Adult; Aged; Antibodies, Viral; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Migration Inhibit | 1979 |
[Immunological monitoring of patients with carcinoma of the lung. Study method and preliminary research].
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Antigens, Neoplasm; B-Lymphocytes; Carcinoembryonic Antigen; Ca | 1979 |
Immunoprofile studies for patients with bronchogenic carcinoma. I. Correlation of pretherapy studies with survival.
Topics: Adult; Age Factors; Aged; Agglutination Tests; B-Lymphocytes; Carcinoma, Bronchogenic; Cytotoxicity | 1977 |
Monitoring of immunosuppression in beagles.
Topics: Animals; Antibodies; Azathioprine; Carcinoma, Bronchogenic; Dinitrochlorobenzene; Disease Models, An | 1977 |
Immunologic testing as a guide to cancer management.
Topics: Antibody Formation; Antigen-Antibody Complex; Breast Neoplasms; Colonic Neoplasms; Complement System | 1979 |
[Prognostic value of skin tests with tuberculin, distreptase and dinitrochlorobenzene in primary lung cancer].
Topics: Dinitrochlorobenzene; Humans; Lung Neoplasms; Skin Tests; Streptodornase and Streptokinase; Tubercul | 1979 |
[Immune response in patients with lung cancer].
Topics: Aged; Dinitrochlorobenzene; Humans; Lung Neoplasms; Middle Aged; Skin Tests; Tuberculin | 1979 |
The relationship between immune reactivity, serum cortisol, and stage of disease in patients with non-oat-cell bronchogenic carcinoma.
Topics: Carcinoma, Bronchogenic; Circadian Rhythm; Dinitrochlorobenzene; Humans; Hydrocortisone; Immunity, C | 1979 |
[The DNCB skin test and its comparison with the radioimmunological determination of CEA in some types of neoplasms].
Topics: Breast Neoplasms; Carcinoembryonic Antigen; Dinitrochlorobenzene; Female; Gastrointestinal Neoplasms | 1979 |
[The epicutaneous DNCB test and CEA determination in neoplasms of the breast, digestive tract, lung and urogenital system].
Topics: Breast Neoplasms; Carcinoembryonic Antigen; Dinitrochlorobenzene; Female; Gastrointestinal Neoplasms | 1979 |
Prognostic significance of skin reactivity in patients with bronchogenic carcinoma grouped according to the TNM classification.
Topics: Antigens; Carcinoma, Bronchogenic; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Lung Neo | 1977 |
Immunocompetence testing in patients with one of the four common operable cancers--a review.
Topics: Breast Neoplasms; Colonic Neoplasms; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans; | 1978 |
Sequential evaluation of DNCB reactivity in patients with primary lung cancer. Correlation with prognosis.
Topics: Adult; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Lung Neoplasms; | 1978 |
[Delayed hypersensitivity tests: PPD, DNCB and distreptase in patients with primary lung cancer].
Topics: Antigens, Bacterial; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Lung Neoplasms; Method | 1978 |
Immunologic aspects of lung cancer.
Topics: Antibodies, Neoplasm; Antibody Formation; Antigens, Neoplasm; Dinitrochlorobenzene; Humans; Immunity | 1977 |
Immunocompetence and spontaneous regression of metastatic renal cell carcinoma.
Topics: Adenocarcinoma; Brain Neoplasms; Dinitrochlorobenzene; Humans; Kidney Neoplasms; Lung Neoplasms; Mal | 1976 |
[Immunologic state of patients with cancer of the lung, pharynx, larynx, thyroid gland, treated with radiation].
Topics: Dinitrochlorobenzene; Humans; Laryngeal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Nitrobenzene | 1976 |
Correlation between phytohemagglutinin skin test and delayed cutaneous hypersensitivity to dinitrochlorobenzene in cancer patients.
Topics: Adult; Aged; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Lectins; Liver Neoplasms; Lung | 1976 |
[Role of immune skin reactions in progressive lung cancer during the administration of OK-432--relation to reactions to DNCB, PPD and Su-PS].
Topics: Adenocarcinoma; Biological Products; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Dinitrochlorob | 1987 |
Epidermal Langerhans cell density in patients with pulmonary malignancies and chronic obstructive pulmonary disease.
Topics: Adult; Aged; Aged, 80 and over; Cell Count; Dinitrochlorobenzene; Glucocorticoids; Humans; Langerhan | 1987 |