dinitrochlorobenzene has been researched along with Local Neoplasm Recurrence in 21 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-nine selected patients with recurrent melanoma (37 locoregional and 22 locoregional and haematogenic) were treated with a combination of topical dinitrochlorobenzene (DNCB) and systemic dacarbazine (DTIC)." | 9.08 | Topical dinitrochlorobenzene combined with systemic dacarbazine in the treatment of recurrent melanoma. ( Hart, AA; Israels, SP; Kroon, BB; Nieweg, OE; Rümke, P; Strobbe, LJ, 1997) |
| "Eighteen patients with multiple recurrences of malignant melanoma without evident distant spread were randomly assigned to treatment with either intralesional Bacillus Calmette-Guerin (BCG) or intralesional dinitrochlorobenzene (DNCB)." | 9.04 | Intralesional treatment of recurrent metastatic cutaneous malignant melanoma: a randomized prospective study of intralesional Bacillus Calmette-Guerin versus intralesional dinitrochlorobenzene. ( Cohen, MH; Felix, EL; Herberman, RB; Jessup, JM; Weese, JL, 1978) |
| "Dinitrochlorobenzene (DNCB) immunotherapy of a recurrent conjunctival papilloma was employed successfully in a 24-year-old man." | 7.66 | Dinitrochlorobenzene immunotherapy of recurrent squamous papilloma of the conjunctiva. ( Cotlier, E; Petrelli, R; Robins, S; Stoessel, K, 1981) |
| "Fifty-nine selected patients with recurrent melanoma (37 locoregional and 22 locoregional and haematogenic) were treated with a combination of topical dinitrochlorobenzene (DNCB) and systemic dacarbazine (DTIC)." | 5.08 | Topical dinitrochlorobenzene combined with systemic dacarbazine in the treatment of recurrent melanoma. ( Hart, AA; Israels, SP; Kroon, BB; Nieweg, OE; Rümke, P; Strobbe, LJ, 1997) |
| "Eighteen patients with multiple recurrences of malignant melanoma without evident distant spread were randomly assigned to treatment with either intralesional Bacillus Calmette-Guerin (BCG) or intralesional dinitrochlorobenzene (DNCB)." | 5.04 | Intralesional treatment of recurrent metastatic cutaneous malignant melanoma: a randomized prospective study of intralesional Bacillus Calmette-Guerin versus intralesional dinitrochlorobenzene. ( Cohen, MH; Felix, EL; Herberman, RB; Jessup, JM; Weese, JL, 1978) |
| "Delayed cutaneous hypersensitivity to 2,3-dinitrochlorobenzene (DNCB) was tested in 419 patients with malignant melanoma to determine whether DNCB reactivity was associated with prognosis." | 3.66 | DNCB reactivity and prognosis in 419 patients with malignant melanoma. ( Braun, DW; Camacho, ES; Fortner, JG; Golbey, RB; Oettgen, HF; Pinsky, CM; Wanebo, HJ, 1981) |
| "Dinitrochlorobenzene (DNCB) immunotherapy of a recurrent conjunctival papilloma was employed successfully in a 24-year-old man." | 3.66 | Dinitrochlorobenzene immunotherapy of recurrent squamous papilloma of the conjunctiva. ( Cotlier, E; Petrelli, R; Robins, S; Stoessel, K, 1981) |
| "Immunotherapy against cancer in animals has been established." | 1.25 | Immunotherapy of malignancy in humans. Current status. ( Eilber, FR; Holmes, EC; Morton, DL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cron, J | 1 |
| Jansa, P | 1 |
| Flamm, J | 2 |
| Sagaster, P | 1 |
| Micksche, M | 1 |
| Foster, DC | 1 |
| Woodruff, JD | 1 |
| Camacho, ES | 1 |
| Pinsky, CM | 3 |
| Braun, DW | 2 |
| Golbey, RB | 1 |
| Fortner, JG | 1 |
| Wanebo, HJ | 2 |
| Oettgen, HF | 2 |
| Burkert, S | 1 |
| Petrelli, R | 1 |
| Cotlier, E | 1 |
| Robins, S | 1 |
| Stoessel, K | 1 |
| Krown, SE | 1 |
| Wong, PP | 1 |
| Strobbe, LJ | 1 |
| Hart, AA | 1 |
| Rümke, P | 1 |
| Israels, SP | 1 |
| Nieweg, OE | 1 |
| Kroon, BB | 1 |
| Holmes, EC | 1 |
| Eilber, FR | 1 |
| Morton, DL | 1 |
| Cohen, MH | 1 |
| Jessup, JM | 1 |
| Felix, EL | 1 |
| Weese, JL | 1 |
| Herberman, RB | 1 |
| Bosworth, JL | 1 |
| Thaler, S | 1 |
| Ghossein, NA | 1 |
| Wanebo, H | 1 |
| Mike, V | 1 |
| Oettgen, H | 1 |
| Bolton, PM | 1 |
| Catalona, WJ | 1 |
| Smolev, JK | 1 |
| Harty, JI | 1 |
| Cunningham, TJ | 1 |
| Daut, D | 1 |
| Wolfgang, PE | 1 |
| Mellyn, M | 1 |
| Maciolek, S | 1 |
| Sponzo, RW | 1 |
| Horton, J | 1 |
| Sigg, C | 1 |
| Schnyder, UW | 1 |
| Novick, NL | 1 |
| Bosniak, SL | 1 |
| Valsecchi, R | 1 |
| Foiadelli, L | 1 |
| Reseghetti, A | 1 |
| Cainelli, T | 1 |
| Shukla, HS | 2 |
| Hughes, LE | 2 |
| Whitehead, RH | 2 |
| Newcombe, RG | 2 |
| Mandel, MA | 1 |
| Kiehn, C | 1 |
1 review available for dinitrochlorobenzene and Local Neoplasm Recurrence
| Article | Year |
|---|---|
DNCB sensitivity in cancer patients. A review based on sequential testing in 430 patients.
Topics: Adenocarcinoma; Adult; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Dinitrochlorob | 1975 |
3 trials available for dinitrochlorobenzene and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Topical dinitrochlorobenzene combined with systemic dacarbazine in the treatment of recurrent melanoma.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemoth | 1997 |
Intralesional treatment of recurrent metastatic cutaneous malignant melanoma: a randomized prospective study of intralesional Bacillus Calmette-Guerin versus intralesional dinitrochlorobenzene.
Topics: Adult; Aged; Antigens; Antigens, Neoplasm; BCG Vaccine; Cell Migration Inhibition; Dinitrochlorobenz | 1978 |
Delayed hypersensitivity and local control of patients treated by radiotherapy for head and neck cancer.
Topics: Adult; Aged; Animals; Clinical Trials as Topic; Dinitrochlorobenzene; Female; Head and Neck Neoplasm | 1976 |
17 other studies available for dinitrochlorobenzene and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Role of phagocytic cells in cancer.
Topics: Anaerobiosis; Antineoplastic Agents; Breast Neoplasms; Complement Activation; Dinitrochlorobenzene; | 1981 |
The value of the DNCB test in bladder cancer. Pretreatment evaluation of immune function and 5-year follow-up of patients with urinary bladder cancer.
Topics: Aged; Dinitrochlorobenzene; Female; Humans; Immunoglobulins; Male; Neoplasm Invasiveness; Neoplasm R | 1984 |
The use of dinitrochlorobenzene in the treatment of vulvar carcinoma in situ.
Topics: Administration, Topical; Adult; Carcinoma in Situ; Dinitrochlorobenzene; Female; Fluorouracil; Human | 1981 |
DNCB reactivity and prognosis in 419 patients with malignant melanoma.
Topics: Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Melanoma; Neoplasm Metastasis; Neoplasm Rec | 1981 |
[The prognostic significance of the immune status (DNCB-test) in patients with carcinoma of the bladder, checked by observation of the course of disease (author's transl)].
Topics: Aged; Dinitrochlorobenzene; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Nitr | 1981 |
Dinitrochlorobenzene immunotherapy of recurrent squamous papilloma of the conjunctiva.
Topics: Adult; Conjunctival Neoplasms; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Immunization | 1981 |
Immunologic reactivity and prognosis in breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Dinitrochlorobenzene; Female; | 1980 |
Immunotherapy of malignancy in humans. Current status.
Topics: Adjuvants, Immunologic; Antigens, Neoplasm; BCG Vaccine; Carcinoma, Basal Cell; Carcinoma, Squamous | 1975 |
Delayed cutaneous hypersensitivity reactions and prognosis in patients with cancer.
Topics: Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Neoplasm Metastasis; Neoplasm Recurrence, L | 1976 |
Prognostic value of host immunocompetence in urologic cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Transitional Cell; Dinitrochlorobenzene; Female; Follow-Up S | 1975 |
A correlation of DNCB-induced delayed cutaneous hypersensitivity reactions and the course of disease in patients with recurrent breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersen | 1976 |
Successful immunotherapy by dinitrochlorobenzene in a case of recurrent acrolentiginous melanoma.
Topics: Administration, Topical; Aged; Dinitrochlorobenzene; Female; Foot Diseases; Humans; Immunotherapy; M | 1990 |
The failure of immunotherapy with dinitrochlorobenzene and Rhus extract for recurrent conjunctival squamous papillomas.
Topics: Administration, Topical; Adult; Conjunctival Neoplasms; Dinitrochlorobenzene; Humans; Immunotherapy; | 1986 |
Generalized urticaria from DNCB.
Topics: Aged; Combined Modality Therapy; Dinitrochlorobenzene; Drug Eruptions; Female; Humans; Immunotherapy | 1986 |
Long-term (5-11 years) follow-up of general immune competence in breast cancer. I. Pre-treatment levels with reference to micrometastasis.
Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunocompetence; Immunog | 1986 |
Long-term follow-up of general immune competence in breast cancer. II. Sequential pre- and post-treatment levels: a 10 year study.
Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunocompetence; Immunog | 1986 |
Cutaneous reactivity in patients with cancer of the head and neck region.
Topics: Age Factors; Aged; Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Drug Hypersensitivity | 1973 |